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Ko Okumura Selected Research

Dermatophagoides farinae antigen f 1

5/2013IL-33-mediated innate response and adaptive immune cells contribute to maximum responses of protease allergen-induced allergic airway inflammation.
1/2008Upregulation of the release of granulocyte-macrophage colony-stimulating factor from keratinocytes stimulated with cysteine protease activity of recombinant major mite allergens, Der f 1 and Der p 1.
1/2006Glycosylation of recombinant proforms of major house dust mite allergens Der p 1 and Der f 1 decelerates the speed of maturation.
7/2005Cystatin A inhibits IL-8 production by keratinocytes stimulated with Der p 1 and Der f 1: biochemical skin barrier against mite cysteine proteases.

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Ko Okumura Research Topics

Disease

35Inflammation
12/2015 - 05/2002
21Hypersensitivity (Allergy)
02/2014 - 05/2002
17Neoplasms (Cancer)
12/2011 - 01/2002
14Infection
05/2015 - 06/2003
14Asthma (Bronchial Asthma)
06/2014 - 08/2002
11Atopic Dermatitis (Atopic Eczema)
06/2014 - 02/2003
8Colitis
01/2014 - 10/2003
7Necrosis
06/2012 - 01/2002
5Psoriasis (Pustulosis Palmaris et Plantaris)
12/2015 - 12/2002
5Wounds and Injuries (Trauma)
11/2011 - 03/2003
5Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
05/2011 - 08/2002
5Allergic Conjunctivitis (Giant Papillary Conjunctivitis)
02/2009 - 07/2002
4Eosinophilia
07/2015 - 10/2003
4Food Hypersensitivity (Food Allergy)
06/2014 - 06/2005
4Arthritis (Polyarthritis)
11/2013 - 10/2002
4Anaphylaxis (Anaphylactic Shock)
01/2012 - 05/2002
4Rheumatoid Arthritis
03/2010 - 10/2002
4Skin Diseases
01/2009 - 12/2002
3Autoimmune Diseases (Autoimmune Disease)
01/2015 - 06/2002
3Hepatitis
12/2012 - 01/2009
3Neoplasm Metastasis (Metastasis)
10/2011 - 03/2005
3Contact Dermatitis (Eczema, Contact)
09/2011 - 09/2010
3Hyperplasia
09/2010 - 02/2007
3Myocarditis (Carditis)
07/2007 - 04/2002
2Melanoma (Melanoma, Malignant)
03/2015 - 01/2013
2Sepsis (Septicemia)
10/2014 - 05/2002
2Bacterial Infections (Bacterial Infection)
07/2013 - 11/2005
2Optic Neuritis (Retrobulbar Neuritis)
10/2012 - 01/2012
2Ischemia
06/2012 - 05/2010
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
09/2011 - 10/2010
2Stroke (Strokes)
02/2011 - 07/2009
2Experimental Arthritis
01/2011 - 05/2007

Drug/Important Bio-Agent (IBA)

23Immunoglobulin E (IgE)IBA
02/2014 - 05/2002
19Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2012 - 01/2002
17CytokinesIBA
07/2015 - 05/2002
11AntigensIBA
01/2015 - 05/2002
10Transforming Growth Factor beta (TGF-beta)IBA
09/2010 - 08/2002
9AllergensIBA
07/2015 - 07/2005
8TNF-Related Apoptosis-Inducing LigandIBA
12/2012 - 10/2002
7ChemokinesIBA
03/2015 - 12/2002
7thymic stromal lymphopoietinIBA
06/2012 - 05/2007
7AntibodiesIBA
12/2011 - 05/2002
6Monoclonal AntibodiesIBA
01/2015 - 06/2006
6OvalbuminIBA
01/2015 - 04/2003
6LigandsIBA
10/2014 - 10/2002
6Dermatophagoides pteronyssinus antigen p 1IBA
12/2011 - 07/2005
5Proteins (Proteins, Gene)IBA
01/2014 - 02/2007
5TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA
12/2011 - 02/2004
4Interleukin-10 (Interleukin 10)IBA
07/2013 - 10/2003
4Immunoglobulin G (IgG)IBA
05/2013 - 10/2002
4Dermatophagoides farinae antigen f 1IBA
05/2013 - 07/2005
4Interleukin-13IBA
05/2013 - 10/2003
4Neutralizing AntibodiesIBA
12/2012 - 06/2005
4Thromboplastin (Tissue Factor)IBA
02/2011 - 07/2009
4MucinsIBA
01/2011 - 02/2007
4Fc Receptors (Fc Receptor)IBA
12/2005 - 06/2002
3Tretinoin (Retinoic Acid)FDA LinkGeneric
03/2015 - 10/2012
3Interleukin-1 (Interleukin 1)IBA
01/2015 - 10/2010
3Dextrans (Dextran)FDA Link
01/2014 - 08/2010
3CollagenIBA
11/2013 - 12/2005
3Interleukin-4 (Interleukin 4)IBA
05/2013 - 10/2003
3Fas Ligand Protein (Fas Ligand)IBA
12/2012 - 01/2005
3InterferonsIBA
12/2012 - 01/2002
3Phosphotransferases (Kinase)IBA
08/2011 - 02/2007
3Reactive Oxygen Species (Oxygen Radicals)IBA
09/2009 - 07/2004
3IgE Receptors (Fc epsilon RI)IBA
01/2009 - 07/2002
3Collagen Type II (Type II Collagen)IBA
05/2007 - 10/2002
2PapainIBA
07/2015 - 05/2013
2Interleukin-2 (IL2)IBA
07/2015 - 10/2003
2Peptide Hydrolases (Proteases)IBA
05/2015 - 02/2009
2Toll-Like Receptors (Toll-Like Receptor)IBA
03/2015 - 05/2002
2Toll-Like Receptor 3IBA
03/2015 - 01/2013
2Tyrosine (L-Tyrosine)FDA Link
01/2015 - 12/2005
2Interleukin-6 (Interleukin 6)IBA
10/2014 - 07/2008
2Interleukin-17 (Interleukin 27)IBA
10/2014 - 10/2012
2sodium sulfate (sodium bisulfate)FDA LinkGeneric
01/2014 - 08/2010
2Type I Tumor Necrosis Factor ReceptorsIBA
12/2012 - 05/2011
2Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
10/2012 - 05/2011
2TNF Receptor-Associated Factor 2 (TRAF2)IBA
10/2012 - 05/2011
2Calcitonin Gene-Related PeptideIBA
10/2012 - 01/2012
2Peroxidase (Myeloperoxidase)IBA
06/2012 - 12/2005
2T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA
12/2011 - 11/2005
2PeptidesIBA
11/2011 - 08/2005
2Interleukin-12 (IL 12)IBA
10/2011 - 06/2007
2Anti-Bacterial Agents (Antibiotics)IBA
05/2011 - 11/2005
2Immunoglobulins (Immunoglobulin)IBA
01/2011 - 04/2003
2Lipoproteins (Lipoprotein)IBA
11/2010 - 06/2002
2Messenger RNA (mRNA)IBA
09/2010 - 10/2003
2amphiregulin (schwannoma-derived growth factor)IBA
09/2010 - 06/2010
2TGF-beta type I receptorIBA
09/2010 - 02/2007
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2010 - 02/2007
2Interferon-gamma (Interferon, gamma)IBA
03/2008 - 02/2003
2Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
01/2008 - 08/2002
2Adenosine Triphosphatases (ATPase)IBA
01/2008 - 06/2005

Therapy/Procedure

9Immunotherapy
12/2011 - 04/2002
4Transplants (Transplant)
10/2008 - 06/2002
3Oral Administration
01/2008 - 06/2005
2Subcutaneous Injections
02/2011 - 07/2004
2Ligation
08/2008 - 04/2005
2Transplantation (Transplant Recipients)
12/2007 - 09/2003