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Thomas O'Dorisio Selected Research

(DOTA(0)-Phe(1)-Tyr(3))octreotide (SMT 487)

10/2010Phase I trial of 90Y-DOTATOC therapy in children and young adults with refractory solid tumors that express somatostatin receptors.
4/2006Potential increased tumor-dose delivery with combined 131I-MIBG and 90Y-DOTATOC treatment in neuroendocrine tumors: a theoretic model.
2/2004Effects of intravenous amino acid administration with Y-90 DOTA-Phe1-Tyr3-Octreotide (SMT487[OctreoTher) treatment.
10/2003Evaluating the clinical effectiveness of 90Y-SMT 487 in patients with neuroendocrine tumors.

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Thomas O'Dorisio Research Topics

Disease

6Neuroendocrine Tumors (Neuroendocrine Tumor)
10/2014 - 10/2003
5Neoplasms (Cancer)
01/2013 - 02/2004
1Carcinoid Tumor (Carcinoid)
10/2014
1Diarrhea
10/2014
1Disease Progression
01/2013
1Stomatitis
01/2013
1Exanthema (Rash)
01/2013
1Paraganglioma (Paragangliomas)
10/2010
1Brain Neoplasms (Brain Tumor)
10/2010
1Multiple Endocrine Neoplasia (Multiple Endocrine Adenomatosis)
10/2010
1Neuroblastoma
10/2010
1Thyroid Neoplasms (Thyroid Cancer)
09/2008
1Chronic Kidney Failure (Chronic Renal Failure)
01/2005
1Anorexia
01/2005
1Vomiting
02/2004
1Nausea
02/2004
1Neoplasm Metastasis (Metastasis)
08/2003

Drug/Important Bio-Agent (IBA)

4DOTA-Tyr(3)- 90Y-octreotideIBA
10/2010 - 08/2003
4(DOTA(0)-Phe(1)-Tyr(3))octreotide (SMT 487)IBA
10/2010 - 10/2003
3Somatostatin Receptors (Somatostatin Receptor)IBA
10/2010 - 08/2003
2Octreotide (Sandostatin)FDA LinkGeneric
10/2014 - 01/2013
1Serotonin (5 Hydroxytryptamine)IBA
10/2014
1everolimusFDA Link
01/2013
1PeptidesIBA
03/2011
1AminesIBA
03/2011
1Peptide Receptors (Peptide Receptor)IBA
10/2010
1Thyrotropin AlfaFDA LinkGeneric
09/2008
13-Iodobenzylguanidine (Iobenguane)IBA
04/2006
1HormonesIBA
01/2005
1LeptinIBA
01/2005
1CreatinineIBA
02/2004
1amino-acid, glucose, and electrolyte solution (Novamine)FDA Link
02/2004
1pentetreotide (OctreoScan)FDA Link
02/2004
1Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
10/2003

Therapy/Procedure

1Radiotherapy
04/2006