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François Nosten Selected Research

artesunate

10/2015Opposite malaria and pregnancy effect on oral bioavailability of artesunate - a population pharmacokinetic evaluation.
3/2015Modeling the dynamics of Plasmodium vivax infection and hypnozoite reactivation in vivo.
1/2015Absence of association between Plasmodium falciparum small sub-unit ribosomal RNA gene mutations and in vitro decreased susceptibility to doxycycline.
7/2014Spiroindolone KAE609 for falciparum and vivax malaria.
3/2013Effect of high-dose or split-dose artesunate on parasite clearance in artemisinin-resistant falciparum malaria.
5/2012Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study.
3/2012Artesunate/dihydroartemisinin pharmacokinetics in acute falciparum malaria in pregnancy: absorption, bioavailability, disposition and disease effects.
3/2011Plasmodium vivax recurrence following falciparum and mixed species malaria: risk factors and effect of antimalarial kinetics.
1/2011Intrahost modeling of artemisinin resistance in Plasmodium falciparum.
7/2009Artemisinin resistance in Plasmodium falciparum malaria.
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François Nosten Research Topics

Disease

50Malaria
10/2015 - 01/2002
43Falciparum Malaria (Plasmodium falciparum Malaria)
10/2015 - 11/2002
23Infection
04/2015 - 11/2002
10Vivax Malaria
01/2015 - 05/2003
4Fever (Fevers)
01/2015 - 12/2002
4Body Weight (Weight, Body)
12/2011 - 07/2006
3Parasitemia
03/2013 - 01/2007
2Scrub Typhus (Typhus, Scrub)
12/2015 - 04/2008
2Birth Weight (Birth Weights)
11/2010 - 02/2007
1Bacterial Infections (Bacterial Infection)
01/2015
1Pneumonia (Pneumonitis)
01/2013
1Bites and Stings (Sting)
07/2012
1Inflammation
11/2010
1Pyelonephritis
01/2010
1Epidemic Louse-Borne Typhus (Typhus)
01/2010
1Respiratory Tract Infections (Respiratory Tract Infection)
01/2010
1Leptospirosis
01/2010
1Glucosephosphate Dehydrogenase Deficiency
01/2010
1Fetal Distress
10/2009
1Uterine Rupture
10/2009
1Diarrhea
01/2009
1Contagious Ecthyma (Orf)
04/2008
1Hypersensitivity (Allergy)
12/2007
1Hearing Loss (Hearing Impairment)
02/2006
1Anemia
09/2005
1Photoallergic Dermatitis (Photoallergy)
04/2005
1Dizziness (Lightheadedness)
12/2002
1Anorexia
12/2002
1Vomiting
12/2002
1Nausea
12/2002
1Spontaneous Abortion (Miscarriage)
03/2002
1Congenital Abnormalities (Deformity)
03/2002
1Tinnitus
03/2002
1Tuberculosis (Tuberculoses)
01/2002
1Acquired Immunodeficiency Syndrome (AIDS)
01/2002

Drug/Important Bio-Agent (IBA)

23artesunateIBA
10/2015 - 12/2002
23artemisinine (artemisinin)IBA
04/2015 - 01/2007
14dihydroquinghaosu (dihydroartemisinin)IBA
10/2015 - 01/2007
14piperaquineIBA
10/2014 - 01/2007
12Chloroquine (Aralen)FDA LinkGeneric
03/2015 - 03/2002
11Mefloquine (Lariam)FDA LinkGeneric
03/2013 - 12/2002
9artemetherFDA Link
10/2015 - 02/2006
9lumefantrineFDA Link
10/2015 - 02/2006
7Quinine (Quinson)FDA Link
01/2015 - 03/2002
5Antimalarials (Antimalarial Agents)IBA
01/2015 - 01/2002
4Carbon MonoxideIBA
07/2012 - 11/2006
3atovaquone-proguanilIBA
09/2005 - 12/2002
2PrimaquineFDA Link
03/2015 - 01/2010
2Biological Markers (Surrogate Marker)IBA
01/2015 - 11/2010
2Amodiaquine (Camoquin)FDA Link
07/2014 - 09/2011
2ArtemisininsIBA
03/2013 - 01/2011
2AntigensIBA
01/2013 - 04/2008
2AntibodiesIBA
01/2013 - 11/2012
2T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA
09/2005 - 06/2004
2Pyrimethamine (Daraprim)FDA Link
08/2004 - 09/2003
1Immunoglobulin M (IgM)IBA
12/2015
1Immunoglobulin G (IgG)IBA
12/2015
1Immunoglobulin A (IgA)IBA
12/2015
1C-Reactive ProteinIBA
01/2015
1Doxycycline (Vibramycin)FDA LinkGeneric
01/2015
1Methylene Blue (Methylthioninium Chloride)FDA Link
01/2015
1procalcitoninIBA
01/2015
1Anti-Bacterial Agents (Antibiotics)IBA
01/2015
1Glycoproteins (Glycoprotein)IBA
11/2014
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
11/2014
1sulfadoxine-pyrimethamine (Fansidar)FDA Link
07/2014
1Complex MixturesIBA
06/2014
1phytohemagglutinin-PIBA
03/2013
1GoldIBA
01/2013
1AN 12IBA
01/2013
1insulin receptor-related receptor (IRR)IBA
01/2013
1Recombinant ProteinsIBA
01/2013
1desethylamodiaquineIBA
09/2011
1ParaffinIBA
11/2010
1Formaldehyde (Formol)FDA Link
11/2010
1InsecticidesIBA
04/2010
1Azithromycin (Zithromax)FDA LinkGeneric
01/2010
1Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA
01/2010
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
01/2009
1ORALIT (ORS)IBA
01/2009
1Clindamycin (Cleocin)FDA LinkGeneric
04/2008
1Hemoglobins (Hemoglobin)IBA
01/2007
1TabletsIBA
11/2006
1antiarrhythmic peptide (AAP)IBA
09/2005
1Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)IBA
06/2005
1Folic Acid (Vitamin M)FDA LinkGeneric
05/2003
1IronIBA
05/2003
1hemozoinIBA
11/2002

Therapy/Procedure

4Chemoprevention
01/2015 - 03/2012
3Aftercare (After-Treatment)
01/2014 - 07/2010
1Ambulatory Care (Outpatient Care)
11/2010
1Resuscitation
10/2009
1Injections
05/2006
1Drug Therapy (Chemotherapy)
01/2002