Takeji Nishikawa Selected Research

Pemphigus (Pemphigus Vulgaris)

07/2008	Novel system evaluating in vivo pathogenicity of desmoglein 3-reactive T cell clones using murine pemphigus vulgaris.
08/2004	Conformational epitope mapping of antibodies against desmoglein 3 in experimental murine pemphigus vulgaris.
05/2004	IgG binds to desmoglein 3 in desmosomes and causes a desmosomal split without keratin retraction in a pemphigus mouse model.
12/2003	Conformational epitope mapping and IgG subclass distribution of desmoglein 3 in paraneoplastic pemphigus.
09/2003	Cloning of canine desmoglein 3 and immunoreactivity of serum antibodies in human and canine pemphigus vulgaris with its extracellular domains.
08/2003	No involvement of IgG autoantibodies against extracellular domains of desmoglein 2 in paraneoplastic pemphigus or inflammatory bowel diseases.
02/2003	Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3.
10/2002	Ultrastructural changes in mice actively producing antibodies to desmoglein 3 parallel those in patients with pemphigus vulgaris.
03/2002	Pathogenic autoantibody production requires loss of tolerance against desmoglein 3 in both T and B cells in experimental pemphigus vulgaris.

9	Pemphigus (Pemphigus Vulgaris) 07/2008 - 03/2002
2	Tinea Pedis (Athlete's Foot) 01/2007 - 05/2006
1	Neoplasms (Cancer) 09/2008
1	Basal Cell Carcinoma (Rodent Ulcer) 09/2008
1	Dermatomyositis (Dermatopolymyositis) 05/2005
1	Epidermolysis Bullosa Dystrophica (Dystrophic Epidermolysis Bullosa) 04/2004
1	Syndrome 01/2004
1	Junctional Epidermolysis Bullosa (Epidermolysis Bullosa Letalis) 01/2004
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 08/2003

7	Desmoglein 3IBA 08/2004 - 03/2002
3	AntibodiesIBA 08/2004 - 10/2002
3	Immunoglobulin G (IgG)IBA 05/2004 - 08/2003
2	4- (2,4- dichlorophenyl)- 1,3- dithiolan- 2- ylidene- 1- imidazolylacetonitrileIBA 01/2007 - 05/2006
2	AutoantibodiesIBA 05/2005 - 08/2003
1	GTP-Binding Proteins (G-Protein)IBA 09/2008
1	DesmogleinsIBA 07/2008
1	bifonazoleIBA 05/2006
1	Keratins (Keratin)IBA 05/2004
1	Nonsense Codon (Nonsense Mutation)IBA 04/2004
1	Integrin beta4IBA 01/2004
1	Desmoglein 2IBA 08/2003