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Johan Neyts Selected Research

Antiviral Agents (Antivirals)

12/2015The future of antivirals: broad-spectrum inhibitors.
9/2015Towards antivirals against chikungunya virus.
3/2015Synergy of entry inhibitors with direct-acting antivirals uncovers novel combinations for prevention and treatment of hepatitis C.
2/2015Bioengineering and semisynthesis of an optimized cyclophilin inhibitor for treatment of chronic viral infection.
9/2014Molecular biology and inhibitors of hepatitis A virus.
5/2014In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks.
11/2013The viral polymerase inhibitor 2'-C-methylcytidine inhibits Norwalk virus replication and protects against norovirus-induced diarrhea and mortality in a mouse model.
10/2013Antibody-dependent enhancement of dengue virus infection is inhibited by SA-17, a doxorubicin derivative.
9/2013The potential of antiviral agents to control classical swine fever: a modelling study.
4/2013Intervention strategies for emerging viruses: use of antivirals.
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Johan Neyts Research Topics

Disease

49Infection
12/2015 - 09/2002
8Hepatocellular Carcinoma (Hepatoma)
08/2015 - 04/2006
8Diarrhea
09/2014 - 04/2006
6Human Influenza (Influenza)
11/2014 - 05/2003
5Myocarditis (Carditis)
11/2015 - 12/2003
4Chronic Hepatitis (Chronic Active Hepatitis)
01/2016 - 10/2013
4Acquired Immunodeficiency Syndrome (AIDS)
02/2015 - 09/2002
4Dengue (Dengue Fever)
11/2014 - 08/2002
4Smallpox (Variola)
02/2006 - 01/2003
4Vaccinia
10/2005 - 01/2003
3Poxviridae Infections
10/2010 - 01/2003
3Chronic Hepatitis B
06/2010 - 01/2008
3Poliomyelitis (Polio)
09/2008 - 04/2008
3Monkeypox
02/2006 - 09/2004
2Inflammation
11/2015 - 08/2006
2Neoplasms (Cancer)
06/2015 - 05/2015
2Hepatitis C
03/2015 - 06/2007
2Hypercholesterolemia
05/2014 - 07/2009
2Pancreatitis
04/2009 - 12/2008
2Cowpox
10/2005 - 09/2004
2Molluscum Contagiosum
09/2004 - 01/2003
2Encephalitis (Encephalitis, Rasmussen)
02/2003 - 02/2003
1Hepatitis B
12/2015
1Virus Diseases (Viral Diseases)
02/2015
1Feline Acquired Immunodeficiency Syndrome (FAIDS)
02/2015
1Hepatitis
09/2014
1Gastroenteritis
09/2014
1Coronavirus Infections
08/2014
1Foot-and-Mouth Disease
05/2014
1Classical Swine Fever (Swine Fever)
09/2013
1Asthma (Bronchial Asthma)
01/2012
1Systemic Inflammatory Response Syndrome (Sepsis Syndrome)
01/2012
1Chronic Obstructive Pulmonary Disease (COPD)
01/2012
1Chronic Hepatitis C
12/2011
1Lassa Fever (Fever, Lassa)
08/2011

Drug/Important Bio-Agent (IBA)

18Antiviral Agents (Antivirals)IBA
12/2015 - 08/2002
11Ribavirin (Virazole)FDA LinkGeneric
01/2016 - 01/2003
9InterferonsIBA
03/2015 - 02/2003
6cidofovir (Vistide)FDA Link
05/2007 - 01/2003
4AntibodiesIBA
03/2015 - 02/2006
4Viral RNAIBA
11/2013 - 04/2005
4Interferon-alpha (Interferon Alfa)FDA Link
10/2013 - 01/2003
4RNA (Ribonucleic Acid)IBA
01/2012 - 04/2005
3Carbon MonoxideIBA
11/2015 - 04/2006
3VaccinesIBA
09/2015 - 02/2006
3Scavenger Receptors (Scavenger Receptor)IBA
03/2015 - 10/2010
3LuciferasesIBA
06/2014 - 04/2006
2claudin 1 (CLDN1)IBA
03/2015 - 10/2010
2Cyclophilins (Cyclophilin)IBA
02/2015 - 06/2014
2Coenzyme A (CoA)IBA
05/2014 - 07/2009
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
05/2014 - 07/2009
2Doxorubicin (Adriamycin)FDA LinkGeneric
10/2013 - 12/2010
2DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)IBA
12/2012 - 04/2009
2Lamivudine (3TC)FDA Link
06/2010 - 01/2008
2adefovir dipivoxil (Hepsera)FDA Link
06/2010 - 01/2008
2tenofovir disoproxil (Viread)FDA Link
06/2010 - 10/2007
2acridoneIBA
05/2009 - 04/2006
2Amantadine (Aman)FDA LinkGeneric
04/2008 - 05/2006
2RimantadineFDA LinkGeneric
04/2008 - 05/2003
2Neuraminidase (Sialidase)IBA
04/2008 - 06/2007
2Oseltamivir (Tamiflu)FDA Link
04/2008 - 06/2007
2DEBIO-025IBA
04/2008 - 04/2006
2Zanamivir (Relenza)FDA Link
04/2008 - 06/2007
2ampligenIBA
01/2004 - 02/2003
1MicroRNAs (MicroRNA)IBA
11/2015
1fluvastatinFDA Link
08/2015
1calcein AMIBA
08/2015
1P-GlycoproteinIBA
08/2015
1OSW 1IBA
05/2015
1erlotinib (CP 358,774)FDA Link
03/2015
1dasatinib (BMS 354825)FDA Link
03/2015
1feralIBA
02/2015
1pirodavirIBA
01/2015
1imidazoleIBA
11/2014
1arbidolIBA
11/2014
16-fluoro-3-hydroxy-2-pyrazinecarboxamideIBA
10/2014
14-boronic acid benzophenoneIBA
06/2014
1OxidoreductasesIBA
06/2014
1Mycophenolic AcidFDA Link
06/2014
1Tacrolimus (Prograf)FDA LinkGeneric
06/2014
1Cyclosporine (Ciclosporin)FDA LinkGeneric
06/2014
1Inosine Monophosphate (IMP)IBA
06/2014
12,6-bis(benzimidazol-2-yl)pyridineIBA
06/2014
1CalcineurinIBA
06/2014
1SteroidsIBA
06/2014
1Immunosuppressive Agents (Immunosuppressants)IBA
06/2014
1UridineIBA
04/2014
12'-C-methylcytidineIBA
11/2013
1PolysaccharidesIBA
12/2012
1Glycoproteins (Glycoprotein)IBA
12/2012
1Ivermectin (Mectizan)FDA Link
08/2012
19- ((cis- 1,2- bis(hydroxymethyl)cycloprop- 1- yl)methyl)guanineIBA
02/2012
1pleconarilIBA
01/2012
1teicoplanin aglyconeIBA
06/2011
1BAY 41-4109IBA
01/2011
19- (3- hydroxy- 2- phosphonomethoxypropyl)- 2,6- diaminopurineIBA
10/2010
1occludinIBA
10/2010

Therapy/Procedure

6Transplants (Transplant)
03/2015 - 09/2002
3Therapeutics
06/2015 - 06/2014
2Oral Administration
10/2005 - 09/2004