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Manuela Neumann Selected Research

Dementia (Dementias)

07/2008	Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
01/2008	Missense Mutations in the Progranulin Gene Linked to Frontotemporal Lobar Degeneration with Ubiquitin-immunoreactive Inclusions Reduce Progranulin Production and Secretion.
10/2007	TDP-43 pathologic lesions and clinical phenotype in frontotemporal lobar degeneration with ubiquitin-positive inclusions.
10/2007	TDP-43 proteinopathy in frontotemporal lobar degeneration and amyotrophic lateral sclerosis: protein misfolding diseases without amyloidosis.
07/2007	TDP-43 proteinopathy: the neuropathology underlying major forms of sporadic and familial frontotemporal lobar degeneration and motor neuron disease.
07/2007	TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions.
05/2007	Absence of heterogeneous nuclear ribonucleoproteins and survival motor neuron protein in TDP-43 positive inclusions in frontotemporal lobar degeneration.
03/2007	TDP-43-positive white matter pathology in frontotemporal lobar degeneration with ubiquitin-positive inclusions.
02/2007	TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations.
10/2006	Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
10/2006	Pathological heterogeneity of frontotemporal lobar degeneration with ubiquitin-positive inclusions delineated by ubiquitin immunohistochemistry and novel monoclonal antibodies.
04/2006	An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies.
01/2005	Tau protein, Abeta42 and S-100B protein in cerebrospinal fluid of patients with dementia with Lewy bodies.

Articles by Research Topic

Disease

13	Dementia (Dementias) 07/2008 - 01/2005
5	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 07/2008 - 10/2006
3	Alzheimer Disease (Alzheimer's Disease) 06/2008 - 01/2003
1	Tauopathies 06/2008
1	Amyloidosis 10/2007
1	Motor Neuron Disease (Primary Lateral Sclerosis) 07/2007
1	Multiple System Atrophy 03/2005
1	Lewy Body Disease (Lewy Body Dementia) 12/2004
1	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 08/2003

Drug/Important Bio-Agent (IBA)

9	protein TDP-43IBA 05/2008 - 10/2006
6	UbiquitinIBA 01/2008 - 10/2006
2	Monoclonal AntibodiesIBA 10/2006 - 04/2006
2	alpha-SynucleinIBA 03/2005 - 12/2004
2	Amyloid (Amyloid Fibrils)IBA 08/2003 - 01/2003
1	DNA (Deoxyribonucleic Acid)IBA 07/2008
1	DNA-Binding Proteins (DNA Binding Protein)IBA 06/2008
1	Proteasome Endopeptidase Complex (Proteasome)IBA 06/2007
1	Heterogeneous-Nuclear Ribonucleoproteins (Informatin)IBA 05/2007
1	S-100 calcium-binding protein beta subunitIBA 01/2005
1	tau Proteins (tau Protein)IBA 01/2005
1	Endopeptidase K (Proteinase K)IBA 12/2004
1	PeptidesIBA 08/2003