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Kutty Selva Nandakumar Selected Research

Arthritis (Polyarthritis)

07/2008Cartilage oligomeric matrix protein induction of chronic arthritis in mice.
01/2008The role of collagen antibodies in mediating arthritis.
10/2007Macrophages suppress T cell responses and arthritis development in mice by producing reactive oxygen species.
10/2007Endoglycosidase treatment abrogates IgG arthritogenicity: importance of IgG glycosylation in arthritis.
01/2007Ethanol prevents development of destructive arthritis.
01/2007Collagen antibody induced arthritis.
02/2006Therapeutic vaccination of active arthritis with a glycosylated collagen type II peptide in complex with MHC class II molecules.
01/2006Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity.
09/2005Efficient promotion of collagen antibody induced arthritis (CAIA) using four monoclonal antibodies specific for the major epitopes recognized in both collagen induced arthritis and rheumatoid arthritis.
03/2005The plasminogen activator/plasmin system is essential for development of the joint inflammatory phase of collagen type II-induced arthritis.
07/2004Antileukoproteinase: modulation of neutrophil function and therapeutic effects on anti-type II collagen antibody-induced arthritis.
01/2004Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells.
11/2003Collagen type II-specific monoclonal antibody-induced arthritis in mice: description of the disease and the influence of age, sex, and genes.
10/2003Genetic control of tolerance to type II collagen and development of arthritis in an autologous collagen-induced arthritis model.
08/2003Induction of arthritis by single monoclonal IgG anti-collagen type II antibodies and enhancement of arthritis in mice lacking inhibitory FcgammaRIIB.

Articles by Research Topic

Disease

15Arthritis (Polyarthritis)
07/2008 - 08/2003
4Experimental Arthritis
10/2007 - 09/2002
2Inflammation
04/2008 - 01/2008
2Rheumatoid Arthritis
09/2005 - 09/2002

Drug/Important Bio-Agent (IBA)

8Collagen Type II (Type II Collagen)IBA
01/2008 - 09/2002
7AntibodiesIBA
01/2008 - 09/2002
4Immunoglobulin G (IgG)IBA
04/2008 - 08/2003
3CollagenIBA
01/2008 - 09/2005
1cartilage matrix proteinIBA
07/2008
1Reactive Oxygen Species (Oxygen Radicals)IBA
10/2007
1Ethanol (Ethyl Alcohol)IBA
01/2007
1glycosylated collagenIBA
02/2006
1Collagen Type IXIBA
01/2006
1Monoclonal AntibodiesIBA
09/2005
1EpitopesIBA
09/2005
1Plasmin (Fibrinolysin)FDA Link
03/2005
1Plasminogen Activators (Plasminogen Activator)IBA
03/2005