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A Nagano Selected Research

JNJ-7706621

7/2012Growth suppression and mitotic defect induced by JNJ-7706621, an inhibitor of cyclin-dependent kinases and aurora kinases.

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A Nagano Research Topics

Disease

6Rheumatoid Arthritis
01/2008 - 01/2000
3Arthritis (Polyarthritis)
11/2002 - 01/2000
3Osteoarthritis
11/2002 - 01/2000
2Neoplasms (Cancer)
07/2012 - 01/2000
2Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy)
12/2007 - 10/2000
2Emery-Dreifuss Muscular Dystrophy (X-Linked Emery-Dreifuss Muscular Dystrophy)
12/2007 - 10/2000
2Breast Neoplasms (Breast Cancer)
01/2001 - 01/2000
2Gouty Arthritis
01/2000 - 01/2000
1Medulloblastoma
10/2012
1Ewing's Sarcoma (Sarcoma, Ewing)
07/2012
1Paraplegia (Spastic Paraplegia)
02/2010
1Atrophy
02/2010
1Alzheimer Disease (Alzheimer's Disease)
02/2010
1Spinal Cord Injuries (Spinal Cord Injury)
02/2010
1Stomach Ulcer (Gastric Ulcer)
09/2007
1Obstetric Paralysis
08/2007
1Infection
02/2007
1Paralysis (Palsy)
02/2007
1Poliomyelitis (Polio)
02/2007
1Bone Resorption
06/2006
1Inflammation
11/2002
1Experimental Arthritis
03/2001
1Hypertrophic Cardiomyopathy (Asymmetric Septal Hypertrophy)
10/2000
1Familial Partial Lipodystrophy (Dunnigan Syndrome)
10/2000
1Nervous System Mercury Poisoning (Minamata Disease)
08/2000
1Hip Fractures (Intertrochanteric Fractures)
04/2000
1Ossification of Posterior Longitudinal Ligament
04/2000
1Hypercalcemia (Milk Alkali Syndrome)
01/2000
1Osteoporosis
01/2000
1Neoplasm Metastasis (Metastasis)
01/2000
1Carcinoma (Carcinomatosis)
01/2000

Drug/Important Bio-Agent (IBA)

2infliximab (Remicade)FDA Link
01/2008 - 06/2006
2Lamin Type A (Lamin A)IBA
12/2007 - 10/2000
2emerinIBA
12/2007 - 10/2000
2Collagen Type I (Type I Collagen)IBA
06/2006 - 04/2000
2deoxypyridinolineIBA
06/2006 - 04/2000
2OsteocalcinIBA
04/2000 - 04/2000
1Protons (Proton)IBA
10/2012
1aurora kinase (aurora A kinase)IBA
07/2012
1Cyclin-Dependent Kinases (cdk Proteins)IBA
07/2012
1JNJ-7706621IBA
07/2012
1Amyloid Precursor Protein Secretases (beta-Secretase)IBA
02/2010
1Amyloid (Amyloid Fibrils)IBA
02/2010
1Presenilin-1IBA
02/2010
1Amyloid beta-PeptidesIBA
02/2010
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2008
1Proteins (Proteins, Gene)IBA
12/2007
1Blood Proteins (Serum Proteins)IBA
09/2007
1Carbon MonoxideIBA
08/2007
1collagen type I trimeric cross-linked peptideIBA
06/2006
1Alkaline PhosphataseIBA
06/2006
1Tissue Inhibitor of Metalloproteinases (TIMP)IBA
11/2002
1Matrix MetalloproteinasesIBA
11/2002
1Staphylococcal enterotoxin FIBA
03/2001
1Fluorouracil (Carac)FDA LinkGeneric
01/2001
1type 1B Limb-girdle muscular dystrophyIBA
10/2000
1MercuryIBA
08/2000
1Biological Markers (Surrogate Marker)IBA
04/2000
1procollagen type I carboxy terminal peptide (PICP)IBA
04/2000
1pyridinolineIBA
04/2000
1Interleukin-16 (Interleukin 16)IBA
01/2000
1Tissue Inhibitor of Metalloproteinase-1IBA
01/2000
1Rheumatoid FactorIBA
01/2000
1diazenedicarboxylic acid bis(N'-methylpiperazide)IBA
01/2000
1Parathyroid Hormone-Related ProteinIBA
01/2000

Therapy/Procedure

1Nerve Transfer
02/2007
1Activities of Daily Living (ADL)
04/2005
1Hip Replacement Arthroplasty (Total Hip Replacement)
11/2002
1Oral Administration
01/2001