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Toyoaki Murohara Selected Research

Nicorandil (SG 75)

5/2007Effect of intravenous nicorandil and preexisting angina pectoris on short- and long-term outcomes in patients with a first ST-segment elevation acute myocardial infarction.
1/2007Efficacy of oral nicorandil in patients with end-stage renal disease: a retrospective chart review after coronary angioplasty in Japanese patients receiving hemodialysis.
2/2006Effects of intravenous nicorandil before reperfusion for acute myocardial infarction in patients with stress hyperglycemia.
10/2005Nicorandil promotes myocardial capillary and arteriolar growth in the failing heart of Dahl salt-sensitive hypertensive rats.
8/2005Impact of a single intravenous administration of nicorandil before reperfusion in patients with ST-segment-elevation myocardial infarction.
7/2003Effect of nicorandil on left ventricular end-diastolic pressure during exercise in patients with hypertrophic cardiomyopathy.

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Toyoaki Murohara Research Topics

Disease

47Ischemia
03/2015 - 03/2002
45Heart Failure
09/2015 - 11/2004
43Myocardial Infarction
11/2015 - 02/2004
33Hypertension (High Blood Pressure)
11/2015 - 11/2003
31Atrial Fibrillation
09/2015 - 10/2004
27Fibrosis (Cirrhosis)
11/2015 - 02/2004
27Inflammation
11/2015 - 01/2004
27Cardiovascular Diseases (Cardiovascular Disease)
09/2015 - 10/2002
22Atherosclerosis
07/2015 - 11/2003
21Coronary Artery Disease (Coronary Atherosclerosis)
08/2014 - 12/2003
20Obesity
06/2015 - 09/2006
15Insulin Resistance
11/2015 - 12/2004
14Kidney Diseases (Kidney Disease)
12/2015 - 07/2009
14Hypertrophy
11/2015 - 07/2005
14Diabetes Mellitus
08/2014 - 01/2004
13Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
11/2014 - 11/2005
13Thrombosis (Thrombus)
04/2014 - 12/2002
12Myocardial Ischemia (Ischemic Heart Diseases)
03/2015 - 10/2005
12Atherosclerotic Plaque (Atheroma)
03/2015 - 01/2008
12Cardiomegaly (Heart Hypertrophy)
02/2015 - 06/2003
11Peripheral Arterial Disease
12/2014 - 07/2008
9Anoxia (Hypoxia)
06/2014 - 01/2003
8Body Weight (Weight, Body)
05/2015 - 06/2003
7Reperfusion Injury
08/2015 - 02/2006
7Hemorrhage
03/2015 - 07/2012
7Chronic Kidney Failure (Chronic Renal Failure)
07/2014 - 01/2007
7Neointima
10/2013 - 01/2005
7Pathologic Constriction (Stenosis)
01/2013 - 01/2004
7Hypercholesterolemia
11/2012 - 07/2003
6Glucose Intolerance
11/2015 - 03/2004
6Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
05/2015 - 07/2003
6Neoplasms (Cancer)
03/2015 - 07/2003
6Type 2 Diabetes Mellitus (MODY)
08/2014 - 05/2007
6Angina Pectoris
08/2013 - 01/2007
6Acute Coronary Syndrome
10/2012 - 11/2004
5Stroke (Strokes)
03/2015 - 01/2012
5Ventricular Tachycardia
01/2015 - 07/2008
5Death (Near-Death Experience)
09/2014 - 11/2004
5Vascular System Injuries
07/2014 - 01/2005
5Ventricular Remodeling
09/2013 - 02/2004
5Vascular Diseases (Vascular Disease)
05/2013 - 08/2007
5Hypertrophic Cardiomyopathy (Asymmetric Septal Hypertrophy)
12/2010 - 07/2003
4Coronary Disease (Coronary Heart Disease)
03/2015 - 09/2006
4Spasm (Spasms)
12/2014 - 06/2004
4Heart Diseases (Heart Disease)
02/2014 - 06/2006

Drug/Important Bio-Agent (IBA)

29AdiponectinIBA
03/2015 - 04/2006
15Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2015 - 01/2003
15Glucose (Dextrose)FDA LinkGeneric
02/2015 - 08/2006
12HDL CholesterolIBA
05/2015 - 06/2007
11C-Reactive ProteinIBA
07/2014 - 04/2006
10AdipokinesIBA
06/2015 - 02/2012
10omega-Chloroacetophenone (Mace)IBA
04/2015 - 11/2004
10Angiotensin Receptors (Angiotensin II Receptor)IBA
01/2014 - 12/2003
9ApolipoproteinsIBA
07/2015 - 10/2003
9Angiotensin IIIBA
02/2015 - 03/2002
8Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
03/2015 - 02/2008
8Insulin (Novolin)FDA Link
12/2014 - 12/2004
7Messenger RNA (mRNA)IBA
11/2015 - 05/2006
7LDL CholesterolIBA
09/2015 - 12/2010
7Lipoproteins (Lipoprotein)IBA
04/2015 - 09/2004
7pitavastatin (itavastatin)FDA Link
03/2015 - 06/2006
7glucuronyl glucosamine glycan sulfate (Vessel)IBA
12/2014 - 03/2004
7AngiotensinsIBA
06/2014 - 12/2009
7Sirolimus (Rapamycin)FDA Link
10/2013 - 11/2006
7Type 1 Angiotensin ReceptorIBA
01/2013 - 03/2002
7erucylphosphocholineIBA
05/2010 - 01/2003
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2015 - 02/2004
6pioglitazone (Actos)FDA Link
01/2015 - 03/2008
6AMP-Activated Protein KinasesIBA
01/2015 - 08/2008
6DobutamineFDA LinkGeneric
05/2013 - 11/2008
6CathepsinsIBA
03/2012 - 11/2006
6Nicorandil (SG 75)IBA
05/2007 - 07/2003
5CollagenIBA
11/2015 - 07/2009
5Apolipoproteins E (ApoE)IBA
07/2015 - 09/2006
5Warfarin (Coumadin)FDA LinkGeneric
03/2015 - 02/2013
5Plasminogen Activator Inhibitor 1IBA
01/2015 - 12/2002
5Amlodipine (Norvasc)FDA LinkGeneric
01/2015 - 07/2010
5Angiotensin Receptor AntagonistsIBA
01/2015 - 12/2003
5valsartan (Vals)FDA Link
01/2015 - 07/2010
5Nitric Oxide (Nitrogen Monoxide)FDA Link
04/2014 - 10/2002
5Calcium Channels (Calcium Channel)IBA
12/2013 - 07/2009
5Brain Natriuretic Peptide (Natrecor)FDA Link
10/2012 - 06/2006
5Matrix MetalloproteinasesIBA
12/2011 - 02/2004
5OxygenIBA
11/2008 - 08/2002
4Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
08/2015 - 05/2010
4CytokinesIBA
07/2015 - 02/2004
4cathepsin SIBA
03/2015 - 11/2006
4NADPH Oxidase (NAD(P)H oxidase)IBA
03/2015 - 01/2004
4Interleukin-6 (Interleukin 6)IBA
01/2015 - 06/2004
4Acetylcholine (Acetylcholine Chloride)FDA Link
12/2014 - 03/2004
4Serum AlbuminIBA
07/2014 - 01/2012
4Eicosapentaenoic AcidIBA
07/2014 - 05/2011

Therapy/Procedure

24Stents
03/2015 - 01/2004
21Renal Dialysis (Hemodialysis)
12/2015 - 08/2006
12Catheters
10/2014 - 07/2004
8Ligation
03/2015 - 02/2004
8Transplantation (Transplant Recipients)
09/2014 - 03/2002
7Cardiac Resynchronization Therapy
09/2015 - 10/2006
7Drug-Eluting Stents
04/2014 - 02/2011
6Angioplasty (Angioplasty, Transluminal)
01/2013 - 01/2007