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Hiromu Murofushi Selected Research

Phosphatidic Acids (Phosphatidic Acid)

1/2014Cyclic phosphatidic acid relieves osteoarthritis symptoms.
1/2012Protection of neuroblastoma Neuro2A cells from hypoxia-induced apoptosis by cyclic phosphatidic acid (cPA).
1/2011Antinociceptive effect of cyclic phosphatidic acid and its derivative on animal models of acute and chronic pain.
1/2007Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid.
8/2006Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis.

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Hiromu Murofushi Research Topics

Disease

5Neoplasms (Cancer)
10/2009 - 05/2002
3Neoplasm Metastasis (Metastasis)
01/2007 - 05/2002
2Osteoarthritis
09/2014 - 01/2014
2Pain (Aches)
01/2014 - 01/2011
2Melanoma (Melanoma, Malignant)
01/2007 - 08/2006
2Shock
06/2003 - 06/2002
1Ischemia
01/2012
1Anoxia (Hypoxia)
01/2012
1Neuroblastoma
01/2012
1Hyperalgesia
01/2011
1Stomach Ulcer (Gastric Ulcer)
06/2003
1Ulcer
06/2003

Drug/Important Bio-Agent (IBA)

5Phosphatidic Acids (Phosphatidic Acid)IBA
01/2014 - 08/2006
2Hyaluronic Acid (Hyaluronan)IBA
09/2014 - 01/2014
2Telomerase (Telomerase Reverse Transcriptase)IBA
10/2009 - 08/2004
2cholesteryl glucosideIBA
06/2003 - 06/2002
1Glial Fibrillary Acidic ProteinIBA
01/2012
1DNA (Deoxyribonucleic Acid)IBA
01/2012
1cobaltous chloride (cobalt(II)chloride)IBA
01/2012
1Cell ExtractsIBA
10/2009
1Messenger RNA (mRNA)IBA
10/2009
1OxygenIBA
01/2007
1Lysophosphatidic Acid ReceptorsIBA
08/2006
1Conditioned Culture MediaIBA
08/2006
1Autocrine Motility FactorIBA
08/2006
1geranylgeranylacetone (teprenone)IBA
06/2003
1HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
06/2002
1heat shock transcription factor (heat shock transcription factors)IBA
06/2002
1CalciumIBA
05/2002

Therapy/Procedure

1Intra-Articular Injections
01/2014
1Ligation
01/2011