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Kimiko Murakami-Murofushi Selected Research

Phosphatidic Acids (Phosphatidic Acid)

9/2015Cyclic phosphatidic acid inhibits the secretion of vascular endothelial growth factor from diabetic human coronary artery endothelial cells through peroxisome proliferator-activated receptor gamma.
10/2014Cyclic phosphatidic acid treatment suppress cuprizone-induced demyelination and motor dysfunction in mice.
1/2014Cyclic phosphatidic acid relieves osteoarthritis symptoms.
1/2012Release of cyclic phosphatidic acid from gelatin-based hydrogels inhibit colon cancer cell growth and migration.
1/2012Protection of neuroblastoma Neuro2A cells from hypoxia-induced apoptosis by cyclic phosphatidic acid (cPA).
1/2011Antinociceptive effect of cyclic phosphatidic acid and its derivative on animal models of acute and chronic pain.
12/2010Effects of cyclic phosphatidic acid on delayed neuronal death following transient ischemia in rat hippocampal CA1.
11/2010Cyclic phosphatidic acid decreases proliferation and survival of colon cancer cells by inhibiting peroxisome proliferator-activated receptor γ.
1/2007Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid.
8/2006Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis.
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Kimiko Murakami-Murofushi Research Topics

Disease

10Neoplasms (Cancer)
02/2012 - 05/2002
6Neoplasm Metastasis (Metastasis)
12/2010 - 05/2002
4Shock
11/2013 - 06/2002
4Melanoma (Melanoma, Malignant)
12/2010 - 06/2003
3Colonic Neoplasms (Colon Cancer)
03/2015 - 11/2010
2Multiple Sclerosis
10/2014 - 10/2010
2Osteoarthritis
09/2014 - 01/2014
2Pain (Aches)
01/2014 - 01/2011
2Ischemia
01/2012 - 12/2010
2Lung Neoplasms (Lung Cancer)
09/2007 - 08/2006
1Neointima
09/2015
1Atherosclerosis
09/2015
1Colitis
03/2015
1Demyelinating Diseases (Demyelinating Disease)
10/2014
1Gaucher Disease (Gaucher's Disease)
11/2013
1Neuroblastoma
01/2012
1Anoxia (Hypoxia)
01/2012
1Experimental Melanoma
05/2011
1Hyperalgesia
01/2011
1Fibrosis (Cirrhosis)
12/2010
1Systemic Scleroderma (Systemic Sclerosis)
12/2010
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
09/2007
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
06/2007
1Adenocarcinoma
06/2004
1Intestinal Neoplasms (Intestinal Cancer)
06/2004
1Body Weight (Weight, Body)
06/2004
1Hepatocellular Carcinoma (Hepatoma)
06/2003
1Ascites
06/2003
1Stomach Ulcer (Gastric Ulcer)
06/2003
1Ulcer
06/2003

Drug/Important Bio-Agent (IBA)

12Phosphatidic Acids (Phosphatidic Acid)IBA
09/2015 - 06/2003
3heat shock transcription factor (heat shock transcription factors)IBA
11/2013 - 06/2002
3HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
11/2013 - 06/2002
3lysophosphatidic acid (MOPA)IBA
12/2010 - 06/2003
2LipidsIBA
09/2015 - 01/2012
2CholesterolIBA
09/2015 - 11/2013
2Proteins (Proteins, Gene)IBA
03/2015 - 06/2003
2Hyaluronic Acid (Hyaluronan)IBA
09/2014 - 01/2014
2Lysophosphatidic Acid ReceptorsIBA
02/2012 - 08/2006
2Telomerase (Telomerase Reverse Transcriptase)IBA
10/2009 - 08/2004
2cholesteryl glucosideIBA
06/2003 - 06/2002
1PPAR gammaIBA
09/2015
1oxidized low density lipoproteinIBA
09/2015
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
09/2015
1sodium sulfate (sodium bisulfate)FDA LinkGeneric
03/2015
1Dihydrotachysterol (AT 10)IBA
03/2015
1Dextrans (Dextran)FDA Link
03/2015
1CuprizoneIBA
10/2014
1GelatinIBA
01/2012
1HydrogelsIBA
01/2012
1cobaltous chloride (cobalt(II)chloride)IBA
01/2012
1DNA (Deoxyribonucleic Acid)IBA
01/2012
1Glial Fibrillary Acidic ProteinIBA
01/2012
1HydrogelIBA
01/2012
1ceramide glucosyltransferaseIBA
05/2011
1alkylglycerophosphoethanolamine phosphodiesteraseIBA
12/2010
1sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
10/2010
1fingolimod (FTY720)FDA Link
10/2010
1Cell ExtractsIBA
10/2009
1Messenger RNA (mRNA)IBA
10/2009
1Neuregulin-1 (Neuregulin 1)IBA
09/2007
1histidine-rich proteinsIBA
09/2007
1pertuzumabIBA
09/2007
1imatinib (Gleevec)FDA Link
06/2007
1OxygenIBA
01/2007
1Conditioned Culture MediaIBA
08/2006
1Autocrine Motility FactorIBA
08/2006
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
08/2006
1Epidermal Growth Factor Receptor (EGF Receptor)IBA
08/2006
1AzoxymethaneIBA
06/2004
1rhoA GTP-Binding ProteinIBA
06/2004
1BombesinIBA
06/2004
1Fibronectins (Fibronectin)IBA
06/2003
1geranylgeranylacetone (teprenone)IBA
06/2003
1Tyrosine (L-Tyrosine)FDA Link
06/2003
1Focal Adhesion Protein-Tyrosine KinasesIBA
06/2003
1CalciumIBA
05/2002

Therapy/Procedure

2Therapeutics
02/2012 - 12/2010
1Intra-Articular Injections
01/2014
1Microspheres (Microsphere)
01/2012
1Ligation
01/2011
1Injections
06/2004