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Katalin Mikecz Selected Research

Arthritis (Polyarthritis)

07/2008Two Loci on Chromosome 15 Control Experimentally Induced Arthritis through the Differential Regulation of IL-6 and Lymphocyte Proliferation.
12/2006Antigen-induced differential gene expression in lymphocytes and gene expression profile in synovium prior to the onset of arthritis.
06/2005T-cell recognition of differentially tolerated epitopes of cartilage proteoglycan aggrecan in arthritis.
09/2004Enhanced neutrophil extravasation and rapid progression of proteoglycan-induced arthritis in TSG-6-knockout mice.
06/2004Induction of arthritis in HLA-DR4-humanized and HLA-DQ8-humanized mice by human cartilage proteoglycan aggrecan but only in the presence of an appropriate (non-MHC) genetic background.
06/2004Expression of L-selectin, but not CD44, is required for early neutrophil extravasation in antigen-induced arthritis.
01/2004Proteoglycan aggrecan-induced arthritis: a murine autoimmune model of rheumatoid arthritis.
01/2003Proteoglycan-induced arthritis: immune regulation, cellular mechanisms, and genetics.
09/2002IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms.
08/2002Cartilage-specific constitutive expression of TSG-6 protein (product of tumor necrosis factor alpha-stimulated gene 6) provides a chondroprotective, but not antiinflammatory, effect in antigen-induced arthritis.
06/2002T and B cell recovery in arthritis adoptively transferred to SCID mice: antigen-specific activation is required for restoration of autopathogenic CD4+ Th1 cells in a syngeneic system.
01/2002Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis.

Articles by Research Topic

Disease

12Arthritis (Polyarthritis)
07/2008 - 01/2002
2Rheumatoid Arthritis
08/2006 - 01/2004
1Bone Resorption
08/2008
1Experimental Arthritis
01/2007
1Inflammation
08/2006
1Dermatitis
09/2005
1Female Infertility
05/2003

Drug/Important Bio-Agent (IBA)

8Proteoglycans (Proteoglycan)IBA
08/2006 - 01/2002
4AntigensIBA
12/2006 - 06/2002
3L-SelectinIBA
08/2006 - 06/2004
3Aggrecans (Aggrecan)IBA
06/2005 - 01/2004
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2003 - 08/2002
1OsteoprotegerinIBA
08/2008
1Interleukin-6 (Interleukin 6)IBA
07/2008
1Tryptophan (L-Tryptophan)FDA Link
01/2007
1EpitopesIBA
06/2005
1Interleukin-4 (Interleukin 4)IBA
09/2002
1Interleukin-12 (IL 12)IBA
09/2002
1CytokinesIBA
01/2002