Retinoblastoma

A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)

Also Known As:

Glioblastoma, Retinal; Glioma, Retinal; Neuroblastoma, Retinal; Familial Retinoblastoma; Hereditary Retinoblastoma; Sporadic Retinoblastoma; Familial Retinoblastomas; Glioblastomas, Retinal; Gliomas, Retinal; Hereditary Retinoblastomas; Neuroblastomas, Retinal; Retinal Glioblastoma; Retinal Glioblastomas; Retinal Glioma; Retinal Gliomas; Retinal Neuroblastoma; Retinal Neuroblastomas; Retinoblastoma, Familial; Retinoblastoma, Hereditary; Retinoblastoma, Sporadic; Retinoblastomas; Retinoblastomas, Familial; Retinoblastomas, Hereditary; Retinoblastomas, Sporadic; Sporadic Retinoblastomas

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Neoplasms: 415397

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Neoplasms by Histologic Type: 1

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Germ Cell and Embryonal Neoplasms: 2625

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Neuroectodermal Tumors: 168

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Neuroepithelial Neoplasms: 218

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Retinoblastoma: 3458

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Glandular and Epithelial Neoplasms: 252

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Neuroepithelial Neoplasms: 218

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Retinoblastoma: 3458

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Nerve Tissue Neoplasms: 1

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Neuroectodermal Tumors: 168

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Neuroepithelial Neoplasms: 218

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Retinoblastoma: 3458

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Neoplasms by Site: 1

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Eye Neoplasms: 21

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Retinal Neoplasms: 46

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Retinoblastoma: 3458

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Eye Diseases: 1323

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Retinal Diseases: 702

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Retinal Neoplasms: 46

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Retinoblastoma: 3458

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Eye Neoplasms: 21

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Retinal Neoplasms: 46

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Retinoblastoma: 3458

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