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Ivan F McMurtry Selected Research

Vasodilator Agents (Vasodilators)

2/2014A novel vascular homing peptide strategy to selectively enhance pulmonary drug efficacy in pulmonary arterial hypertension.
1/2010Rho kinase-mediated vasoconstriction in pulmonary hypertension.
1/2008Rho kinase-mediated vasoconstriction in rat models of pulmonary hypertension.
3/2005Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension.

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Ivan F McMurtry Research Topics

Disease

26Anoxia (Hypoxia)
07/2015 - 02/2002
21Pulmonary Hypertension (Ayerza Syndrome)
02/2015 - 04/2002
6Right Ventricular Hypertrophy
12/2014 - 08/2004
4Fibrosis (Cirrhosis)
06/2013 - 08/2002
3Hypertrophy
02/2015 - 01/2011
1Vascular Diseases (Vascular Disease)
07/2015
1Diastolic Heart Failure
12/2014
1Ventricular Remodeling
12/2014
1Disease Progression
05/2013
1Aneurysm (Aneurysms)
06/2010
1Bronchopulmonary Dysplasia
08/2004
1Liver Cirrhosis (Hepatic Cirrhosis)
08/2002
1Hepatopulmonary Syndrome
08/2002

Drug/Important Bio-Agent (IBA)

9rho-Associated KinasesIBA
01/2010 - 01/2003
6Idiopathic pulmonary hypertensionIBA
07/2015 - 06/2010
5MonocrotalineIBA
06/2013 - 01/2008
5Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2010 - 08/2002
4Dehydroepiandrosterone (DHEA)IBA
12/2014 - 06/2007
4Vasodilator Agents (Vasodilators)IBA
02/2014 - 03/2005
4Carbon MonoxideIBA
02/2014 - 08/2002
4Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
06/2010 - 08/2004
3Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA
02/2015 - 10/2014
3Glucose (Dextrose)FDA LinkGeneric
02/2015 - 06/2010
3NADP (NADPH)IBA
12/2014 - 01/2006
3SU 5416 (SU5416)IBA
12/2013 - 08/2004
2Reactive Oxygen Species (Oxygen Radicals)IBA
12/2014 - 06/2010
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2008 - 08/2004
2Guanylate Cyclase (Guanylyl Cyclase)IBA
06/2007 - 01/2006
2Y 27632IBA
03/2005 - 10/2004
2Endothelin B ReceptorIBA
02/2005 - 04/2002
2Heme Oxygenase-1IBA
02/2005 - 08/2002
1monomethoxypolyethylene glycol (MPEG)IBA
07/2015
1Histones (Histone)IBA
02/2015
1Cyclin AIBA
02/2015
1myocardinIBA
02/2015
1Proteins (Proteins, Gene)IBA
02/2015
1Acetyl Coenzyme A (Acetyl-CoA)IBA
12/2014
1pyridineIBA
12/2014
1A 17 (A-17)IBA
12/2014
1Matrix Metalloproteinase 2 (Gelatinase A)IBA
05/2013
1Alprostadil (Muse)FDA LinkGeneric
05/2013
1polylactic acid-polyglycolic acid copolymer (PLGA)IBA
05/2013
1Proliferating Cell Nuclear Antigen (PCNA)IBA
05/2013
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
10/2011
1sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
07/2011
1glucuronyl glucosamine glycan sulfate (Vessel)IBA
06/2010
1NAD (NADH)IBA
06/2010
1Adenosine Triphosphate (ATP)IBA
06/2010
1Adenosine Diphosphate (ADP)IBA
06/2010
1Pyruvic Acid (Pyruvate)IBA
06/2010
1Myosin Light Chains (Myosin Essential Light Chain)IBA
06/2010
1OxidoreductasesIBA
06/2010
1Small Interfering RNA (siRNA)IBA
06/2010
1Serotonin (5 Hydroxytryptamine)IBA
06/2010
1ActomyosinIBA
01/2010
1Nifedipine (Adalat)FDA LinkGeneric
01/2010
1Epoprostenol (Prostacyclin)FDA LinkGeneric
01/2010
1tebufenozide (Mimic)IBA
01/2008
1atorvastatin (Lipitor)FDA Link
09/2007
1fasudil (AT 877)IBA
04/2007
1rosiglitazone (Avandia)FDA Link
04/2007
1platelet-derived growth factor BB (becaplermin)FDA Link
07/2006
1Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA
07/2006
1GuanosineIBA
12/2005
1Endothelin A ReceptorIBA
02/2005
1Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA
11/2004
1tin protoporphyrin IXIBA
11/2004
1Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
10/2004
1ThapsigarginIBA
05/2003
1endothelium-dependent hyperpolarization factor (EDHF)IBA
05/2003
1Nitric Oxide Synthase (NO Synthase)IBA
08/2002
1Endothelins (Endothelin)IBA
04/2002
1Messenger RNA (mRNA)IBA
04/2002
1RyanodineIBA
02/2002
1Adenosine Triphosphatases (ATPase)IBA
02/2002

Therapy/Procedure

4Subcutaneous Injections
12/2013 - 08/2004
2Ligation
02/2005 - 08/2002
1Pneumonectomy (Lung Volume Reduction)
01/2008
1Aftercare (After-Treatment)
06/2007