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Sandra M McLachlan Selected Research

Hyperthyroidism

06/2006Probing the genetic basis for thyrotropin receptor antibodies and hyperthyroidism in immunized CXB recombinant inbred mice.
11/2005Gene expression profiles differ markedly in mouse strains that are (or are not) susceptible to hyperthyroidism induced using thyrotropin receptor-expressing adenovirus.
12/2004"Hijacking" the thyrotropin receptor: A chimeric receptor-lysosome associated membrane protein enhances deoxyribonucleic acid vaccination and induces Graves' hyperthyroidism.
08/2004Schistosoma mansoni and alpha-galactosylceramide: prophylactic effect of Th1 Immune suppression in a mouse model of Graves' hyperthyroidism.
04/2003Prevention of autoantibody-mediated Graves'-like hyperthyroidism in mice with IL-4, a Th2 cytokine.

Articles by Research Topic

Disease

7Graves Disease (Basedow Disease)
07/2008 - 07/2002
5Hyperthyroidism
06/2006 - 04/2003

Drug/Important Bio-Agent (IBA)

8Thyrotropin Receptors (Thyrotropin Receptor)IBA
07/2008 - 06/2003
2AutoantibodiesIBA
01/2004 - 07/2002
1Blocking AntibodiesIBA
07/2008
1AntibodiesIBA
06/2006
1cathepsin SIBA
12/2005
1DNA (Deoxyribonucleic Acid)IBA
12/2004
1Membrane Proteins (Integral Membrane Proteins)IBA
12/2004
1alpha-galactosylceramideIBA
08/2004
1Interleukin-4 (Interleukin 4)IBA
04/2003
1Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
07/2002