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Emanuela Mazzon Selected Research

thioglucosidase

1/20154(α-l-rhamnosyloxy)-benzyl isothiocyanate, a bioactive phytochemical that attenuates secondary damage in an experimental model of spinal cord injury.
1/2015Tuscan black kale sprout extract bioactivated with myrosinase: a novel natural product for neuroprotection by inflammatory and oxidative response during cerebral ischemia/reperfusion injury in rat.
12/2014(RS)-glucoraphanin purified from Tuscan black kale and bioactivated with myrosinase enzyme protects against cerebral ischemia/reperfusion injury in rats.
11/2013RS-Glucoraphanin bioactivated with myrosinase treatment counteracts proinflammatory cascade and apoptosis associated to spinal cord injury in an experimental mouse model.
9/2013Anti-inflammatory and anti-apoptotic effects of (RS)-glucoraphanin bioactivated with myrosinase in murine sub-acute and acute MPTP-induced Parkinson's disease.
8/2013Protective role of (RS )-glucoraphanin bioactivated with myrosinase in an experimental model of multiple sclerosis.

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Emanuela Mazzon Research Topics

Disease

122Inflammation
09/2015 - 01/2002
46Spinal Cord Injuries (Spinal Cord Injury)
09/2015 - 02/2005
32Ischemia
12/2014 - 08/2002
31Shock
06/2012 - 03/2002
30Edema
10/2015 - 05/2002
29Myelitis
01/2012 - 02/2005
28Necrosis
10/2011 - 01/2002
28Colitis
08/2011 - 05/2002
27Reperfusion Injury
01/2015 - 01/2002
27Lung Injury
10/2011 - 01/2002
25Pleurisy (Pleuritis)
01/2012 - 01/2002
24Body Weight (Weight, Body)
05/2012 - 10/2002
18Pancreatitis
07/2012 - 05/2002
18Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2010 - 05/2002
16Wounds and Injuries (Trauma)
09/2015 - 07/2002
15Multiple Organ Failure (MODS)
09/2011 - 10/2002
14Pneumonia (Pneumonitis)
10/2011 - 03/2004
11Septic Shock (Toxic Shock Syndrome)
01/2012 - 11/2002
11Arthritis (Polyarthritis)
01/2012 - 10/2002
10Experimental Arthritis
12/2011 - 01/2002
9Hemorrhage
05/2012 - 05/2002
9Periodontitis
05/2011 - 06/2005
9Weight Loss (Weight Reduction)
02/2009 - 07/2002
8Diarrhea
08/2006 - 05/2002
6Fibrosis (Cirrhosis)
09/2015 - 01/2006
6Anoxia (Hypoxia)
04/2009 - 12/2004
5Multiple Sclerosis
10/2015 - 08/2013
5Acute Lung Injury
01/2012 - 07/2002
4Brain Ischemia (Cerebral Ischemia)
01/2015 - 02/2011
4Aneurysm (Aneurysms)
11/2013 - 08/2011
4Neoplasms (Cancer)
01/2012 - 08/2006

Drug/Important Bio-Agent (IBA)

533-nitrotyrosineIBA
06/2015 - 05/2002
41Peroxidase (Myeloperoxidase)IBA
11/2011 - 02/2003
39Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2010 - 02/2003
33CarrageenanIBA
01/2012 - 01/2002
28CytokinesIBA
01/2015 - 06/2002
24Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
12/2014 - 01/2002
22ZymosanIBA
09/2011 - 01/2002
20Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
09/2015 - 01/2002
202,4-dinitrofluorobenzene sulfonic acidIBA
08/2011 - 07/2002
18NF-kappa B (NF-kB)IBA
12/2014 - 01/2002
18Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
12/2014 - 01/2002
16Caerulein (Ceruletide)IBA
07/2012 - 05/2002
16PPAR alphaIBA
01/2010 - 10/2004
14Interleukin-1beta (Interleukin 1 beta)IBA
04/2009 - 01/2002
13Lipase (Acid Lipase)FDA Link
07/2012 - 05/2002
13Peroxisome Proliferator-Activated Receptors (PPAR)IBA
07/2012 - 12/2004
13AmylasesFDA Link
07/2012 - 05/2002
13Transcription Factors (Transcription Factor)IBA
02/2011 - 01/2002
13DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
05/2010 - 02/2005
12Peroxynitrous Acid (Peroxynitrite)IBA
11/2010 - 11/2002
11Nitric Oxide (Nitrogen Monoxide)FDA Link
10/2011 - 01/2002
11Bleomycin (Blenoxane)FDA LinkGeneric
07/2011 - 01/2005
11Poly Adenosine Diphosphate RiboseIBA
07/2011 - 08/2002
10P-SelectinIBA
01/2015 - 01/2002
9Collagen Type II (Type II Collagen)IBA
12/2011 - 10/2002
9Interleukin-6 (Interleukin 6)IBA
01/2011 - 06/2002
9DNA (Deoxyribonucleic Acid)IBA
02/2007 - 01/2002
8Dexamethasone (Maxidex)FDA LinkGeneric
09/2015 - 06/2005
8MelatoninIBA
11/2010 - 04/2005
8LigandsIBA
02/2010 - 12/2004
8Reactive Oxygen Species (Oxygen Radicals)IBA
06/2006 - 07/2002
7Proteins (Proteins, Gene)IBA
07/2012 - 01/2008
7Fas Ligand Protein (Fas Ligand)IBA
11/2011 - 11/2006
7Nitric Oxide Synthase (NO Synthase)IBA
11/2011 - 05/2002
7Tyrosine (L-Tyrosine)FDA Link
05/2011 - 11/2005
7Superoxides (Superoxide)IBA
11/2010 - 07/2002
7Uridine Triphosphate (UTP)IBA
02/2010 - 02/2005
7salicylhydroxamic acid (SHAM)IBA
01/2010 - 01/2004
6GlucocorticoidsIBA
10/2015 - 02/2009
6thioglucosidaseIBA
01/2015 - 08/2013
6GW0742IBA
07/2012 - 01/2010
6TeaIBA
11/2009 - 01/2005
6Interleukin-10 (Interleukin 10)IBA
03/2009 - 07/2002
6InterleukinsIBA
06/2008 - 08/2002
6TNFR-Fc fusion protein (etanercept)FDA Link
05/2008 - 03/2006
5Protein Kinases (Protein Kinase)IBA
05/2012 - 04/2008
5olprinoneIBA
10/2011 - 01/2010
5NADPH Oxidase (NAD(P)H oxidase)IBA
07/2011 - 02/2005
5acetovanillone (apocynin)IBA
03/2011 - 02/2005
5Transforming Growth Factor beta (TGF-beta)IBA
01/2011 - 08/2006
5Cyclooxygenase 2 (Cyclooxygenase-2)IBA
11/2010 - 03/2006
5Fatty Acids (Saturated Fatty Acids)IBA
01/2010 - 02/2008
5CollagenIBA
10/2009 - 01/2005
5Thalidomide (Thalomid)FDA Link
09/2009 - 06/2005
5Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
06/2008 - 10/2004
5Glycogen Synthase (Synthase I)IBA
12/2007 - 05/2006
5SilkFDA Link
02/2007 - 06/2005
5Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA
04/2006 - 06/2003
5M 40403IBA
12/2005 - 07/2002
5Superoxide DismutaseIBA
06/2005 - 07/2002
4Caspase 3 (Caspase-3)IBA
06/2015 - 11/2009
4glucoraphaninIBA
12/2014 - 08/2013
4palmidrolIBA
06/2012 - 07/2008
4Dimethyl Sulfoxide (DMSO)FDA LinkGeneric
05/2012 - 12/2003
4PD 98059IBA
05/2012 - 04/2008

Therapy/Procedure

34Laminectomy
01/2015 - 02/2005
15Intraperitoneal Injections
07/2012 - 05/2002
7Ligation
05/2011 - 10/2005
5Surgical Instruments (Clip)
11/2013 - 09/2007