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Sabatino Maione Selected Research

Formaldehyde (Formol)

9/2014Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist.
10/2013Piperazinyl carbamate fatty acid amide hydrolase inhibitors and transient receptor potential channel modulators as "dual-target" analgesics.
10/2013Platelet-rich plasma exerts antinociceptive activity by a peripheral endocannabinoid-related mechanism.
2/2013Palmitoylethanolamide reduces formalin-induced neuropathic-like behaviour through spinal glial/microglial phenotypical changes in mice.
1/2013Effects of a metabotropic glutamate receptor subtype 7 negative allosteric modulator in the periaqueductal grey on pain responses and rostral ventromedial medulla cell activity in rat.
9/2012Palvanil, a non-pungent capsaicin analogue, inhibits inflammatory and neuropathic pain with little effects on bronchopulmonary function and body temperature.
6/2012Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: potent and selective CB2 cannabinoid receptor inverse agonists.
1/2012Salvinorin A reduces mechanical allodynia and spinal neuronal hyperexcitability induced by peripheral formalin injection.
9/2011Ultrapotent effects of salvinorin A, a hallucinogenic compound from Salvia divinorum, on LPS-stimulated murine macrophages and its anti-inflammatory action in vivo.
8/2010Investigations on the 4-quinolone-3-carboxylic acid motif. 3. Synthesis, structure-affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3-carboxamides as highly selective cannabinoid-2 receptor ligands.
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Sabatino Maione Research Topics

Disease

46Pain (Aches)
10/2015 - 06/2002
25Neuralgia (Stump Neuralgia)
10/2015 - 03/2004
24Hyperalgesia
06/2015 - 05/2004
8Inflammation
08/2014 - 06/2010
2Obesity
01/2016 - 01/2015
2Peripheral Nervous System Diseases (PNS Diseases)
10/2015 - 01/2009
2Osteoporosis
12/2014 - 05/2011
2Chronic Hepatitis C
02/2014 - 01/2014
2Liver Diseases (Liver Disease)
02/2014 - 01/2012
2Contracture
08/2009 - 02/2007
2Gliosis
03/2008 - 05/2007
1Ataxia (Dyssynergia)
02/2015
1Bronchial Hyperreactivity
01/2015
1Colonic Neoplasms (Colon Cancer)
01/2015
1Iron Overload
12/2014
1beta-Thalassemia (Cooley's Anemia)
12/2014
1Neurodegenerative Diseases (Neurodegenerative Disease)
02/2014
1Nervous System Diseases (Neurological Disorders)
02/2014
1Chronic Hepatitis (Chronic Active Hepatitis)
02/2014
1Autistic Disorder (Autism)
11/2013
1Absence Epilepsy (Absence Seizure)
06/2013
1Hypersensitivity (Allergy)
03/2013
1Hypothermia
09/2012
1Pervasive Child Development Disorders
07/2012
1Celiac Disease (Celiac Sprue)
07/2012
1Fatty Liver
01/2012
1Fibrosis (Cirrhosis)
01/2012

Drug/Important Bio-Agent (IBA)

16Formaldehyde (Formol)FDA Link
09/2014 - 06/2002
13Endocannabinoids (Endocannabinoid)IBA
01/2016 - 03/2006
10Glutamic Acid (Glutamate)FDA Link
06/2014 - 03/2004
9CarrageenanIBA
10/2013 - 05/2004
8Cannabinoid Receptors (Cannabinoid Receptor)IBA
01/2015 - 08/2006
8Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
06/2014 - 09/2008
5Serotonin (5 Hydroxytryptamine)IBA
10/2015 - 05/2004
5metabotropic glutamate receptor 8IBA
06/2014 - 09/2008
5anandamide (arachidonylethanolamide)IBA
04/2011 - 08/2006
4metabotropic glutamate receptor 7IBA
06/2015 - 09/2008
4PlasticsIBA
01/2015 - 04/2009
3arachidonoylserotoninIBA
10/2013 - 12/2007
3palmidrolIBA
06/2013 - 01/2011
3gamma-Aminobutyric Acid (GABA)IBA
03/2013 - 07/2007
3metabotropic glutamate receptor 5IBA
03/2013 - 05/2004
3CaspasesIBA
11/2012 - 01/2009
3Capsaicin (Zostrix)FDA Link
09/2012 - 12/2007
3TRPV1 receptorIBA
01/2010 - 04/2008
22-arachidonylglycerol (2-arachidonoylglycerol)IBA
01/2016 - 10/2006
2LigandsIBA
02/2015 - 06/2014
2Purinergic P1 Receptors (Adenosine Receptor)IBA
01/2015 - 01/2012
2AdenosineFDA LinkGeneric
01/2015 - 01/2012
2CytokinesIBA
08/2014 - 08/2006
2Nerve Growth Factors (Neurotrophins)IBA
02/2014 - 12/2011
2CB2 Cannabinoid ReceptorIBA
11/2013 - 05/2011
2N-Methylaspartate (NMDA)IBA
11/2012 - 12/2009
2Mesylates (Mesylate)IBA
03/2012 - 10/2006
2salvinorin AIBA
01/2012 - 09/2011
2KaolinIBA
01/2012 - 09/2008
2cysteinyl-leukotrieneIBA
08/2009 - 02/2007
2Messenger RNA (mRNA)IBA
01/2009 - 02/2007
2Interleukin-10 (Interleukin 10)IBA
02/2007 - 08/2006
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2007 - 08/2006
2N-(4-hydroxyphenyl)arachidonylamide (AM404)IBA
10/2006 - 08/2006
1LeptinIBA
01/2016
1orexins (orexin)IBA
01/2016
1Dopamine (Intropin)FDA LinkGeneric
10/2015
1gabapentin (Neurontin)FDA LinkGeneric
02/2015
1MT2 Melatonin ReceptorIBA
02/2015
1N- (2- ((3- bromophenyl)- (4- fluorophenyl)amino)ethyl)acetamideIBA
02/2015
1acetamideIBA
02/2015
1HormonesIBA
01/2015
1Adenosine KinaseIBA
01/2015
1D-Aspartic Acid (D Aspartate)IBA
01/2015
1oxaliplatin (Eloxatin)FDA LinkGeneric
01/2015
1OvalbuminIBA
01/2015
1Adenosine A3 ReceptorIBA
01/2015
1IronIBA
12/2014
1tartrate-resistant acid phosphatase (TSAP)IBA
12/2014
1AnkyrinsIBA
09/2014
1Monoclonal AntibodiesIBA
08/2014
1Analgesics (Analgesic Drugs)IBA
02/2014
1RNA (Ribonucleic Acid)IBA
02/2014
1Nerve Growth Factor (NGF)IBA
02/2014
1Brain-Derived Neurotrophic Factor (BDNF)IBA
02/2014
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
06/2013
1Liposomes (Liposome)IBA
03/2013
1zoledronic acid (zoledronate)FDA Link
03/2013
1GABA-A Receptors (GABA(A) Receptor)IBA
03/2013
1BicucullineIBA
03/2013
1metabotropic glutamate receptor type 1IBA
03/2013
1TRPC Cation ChannelsIBA
01/2013
1alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA
11/2012
1AMPA Receptors (AMPA Receptor)IBA
11/2012
1Glutens (Glutelin)IBA
07/2012
11,3-dipropyl-8-cyclopentylxanthineIBA
01/2012
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
01/2012
1Non-alcoholic Fatty Liver DiseaseIBA
01/2012
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
01/2012

Therapy/Procedure

3Analgesia
06/2014 - 12/2009
1Ligation
02/2015
1Therapeutics
01/2015
1Chelation Therapy (Therapy, Chelation)
12/2014