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Irene Lorand-Metze Selected Research

Refractory Anemia with Excess of Blasts (RAEM)

1/2013Immunophenotyping in myelodysplastic syndromes can add prognostic information to well-established and new clinical scores.
6/2007Reduced expression of FLIP SHORT in bone marrow of low risk myelodysplastic syndrome.
1/2006Maturation-associated immunophenotypic abnormalities in bone marrow B-lymphocytes in myelodysplastic syndromes.
2/2004Flow cytometric analysis of the expression of Fas/Fasl in bone marrow CD34+ cells in myelodysplastic syndromes: relation to disease progression.

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Irene Lorand-Metze Research Topics

Disease

8Neoplasms (Cancer)
10/2015 - 11/2007
6Multiple Myeloma
10/2012 - 11/2007
5Neutropenia
01/2013 - 10/2006
4BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
08/2015 - 01/2011
4Refractory Anemia with Excess of Blasts (RAEM)
01/2013 - 02/2004
4Sepsis (Septicemia)
01/2013 - 01/2010
3Leukemia
02/2014 - 01/2011
3Septic Shock (Toxic Shock Syndrome)
01/2013 - 01/2010
3Hodgkin Disease (Hodgkin's Disease)
12/2010 - 06/2009
2Myelodysplastic Syndromes (Myelodysplastic Syndrome)
02/2014 - 03/2003
2Fever (Fevers)
01/2013 - 01/2011
2Disease Progression
10/2012 - 11/2007
2Acute Promyelocytic Leukemia
01/2012 - 01/2010
2Lymphoma (Lymphomas)
06/2008 - 03/2003
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
04/2008 - 01/2006
1Primary Myelofibrosis (Myelosclerosis)
10/2015
1Mastocytosis (Mast-Cell Disease)
10/2014
1Systemic Mastocytosis
10/2014
1Hematologic Neoplasms (Hematological Malignancy)
02/2014
1Hemorrhage
01/2012
1Frontotemporal Lobar Degeneration (Semantic Dementia)
01/2012
1Leukocytosis (Pleocytosis)
01/2012
1Infection
01/2011
1Communicable Diseases (Infectious Diseases)
10/2006
1Toxoplasmosis
10/2006
1Autoimmune Diseases (Autoimmune Disease)
10/2006
1Hepatitis B
10/2006
1Thyroid Diseases (Thyroid Disease)
10/2006
1Graves Disease (Basedow Disease)
04/2006
1Pancytopenia
04/2006
1Aplastic Anemia (Anemia, Hypoplastic)
04/2006
1Sickle Cell Anemia (Hemoglobin S Disease)
01/2005

Drug/Important Bio-Agent (IBA)

4imatinib (Gleevec)FDA Link
08/2015 - 01/2011
4ChromatinIBA
01/2012 - 01/2006
3Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
08/2015 - 01/2013
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2013 - 01/2011
3Biological Markers (Surrogate Marker)IBA
01/2013 - 01/2010
3Proteins (Proteins, Gene)IBA
01/2013 - 03/2003
2StathminIBA
10/2015 - 02/2014
2Messenger RNA (mRNA)IBA
10/2015 - 06/2007
2dasatinib (BMS 354825)FDA Link
08/2015 - 10/2014
2CytokinesIBA
01/2011 - 01/2005
2Glutathione Transferase (Glutathione S-Transferase)IBA
12/2010 - 06/2009
2Folic Acid (Vitamin M)FDA LinkGeneric
03/2008 - 10/2006
1INCB018424IBA
10/2015
14- methyl- N- (3- (4- methylimidazol- 1- yl)- 5- (trifluoromethyl)phenyl)- 3- ((4- pyridin- 3- ylpyrimidin- 2- yl)amino)benzamide (nilotinib)FDA Link
08/2015
1CalreticulinIBA
05/2015
1PKC412IBA
10/2014
1tebufenozide (Mimic)IBA
01/2013
15q- syndromeIBA
01/2013
1Angiopoietin-2IBA
01/2013
1Angiopoietin-1IBA
01/2013
1Tyrosine (L-Tyrosine)FDA Link
01/2013
1Thalidomide (Thalomid)FDA Link
10/2012
1Dexamethasone (Maxidex)FDA LinkGeneric
10/2012
1HLA-DR Antigens (HLA-DR)IBA
01/2012
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2012
1ThrombinFDA Link
01/2012
1Janus Kinase 2IBA
01/2011
1VaccinesIBA
01/2011
1nucleophosminIBA
01/2011
1fms-Like Tyrosine Kinase 3IBA
01/2011
1Serum AlbuminIBA
12/2010
1Alkylating AgentsIBA
12/2010
1AnthracyclinesIBA
12/2010
1AIDA protocolIBA
01/2010
1Mitoxantrone (Novantrone)FDA LinkGeneric
01/2010
1Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric
01/2010
1Benzene (Benzole)IBA
10/2009
1Glutathione S-Transferase piIBA
06/2009
1glutathione S-transferase T1IBA
06/2009
1Thymidylate SynthaseIBA
03/2008
1methionine synthase reductaseIBA
03/2008
15-Methyltetrahydrofolate-Homocysteine S-Methyltransferase (Methyltetrahydrofolate Homocysteine Methyltransferase)IBA
03/2008
1Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA
03/2008
1Methionine (L-Methionine)FDA Link
03/2008
1Codon (Codons)IBA
11/2007
1IronIBA
10/2006
1Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
10/2006
1EnzymesIBA
10/2006
1Rheumatoid FactorIBA
10/2006
1Blood Proteins (Serum Proteins)IBA
10/2006
1Thyroxine (Levothyroxine)FDA LinkGeneric
10/2006
1Antinuclear AntibodiesIBA
10/2006
1Cyclic neutropeniaIBA
10/2006
1Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric
10/2006
1Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA
04/2006
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
04/2006
1Prednisone (Sone)FDA LinkGeneric
04/2006
1Methimazole (Thiamazole)FDA LinkGeneric
04/2006
1Cyclosporine (Ciclosporin)FDA LinkGeneric
04/2006
1Antithyroid Agents (Antithyroid Drugs)IBA
04/2006
1AntigensIBA
01/2006

Therapy/Procedure

6Drug Therapy (Chemotherapy)
01/2013 - 06/2008
2Hematopoietic Stem Cell Transplantation
10/2012 - 12/2009
2Transplants (Transplant)
10/2012 - 02/2002
1Salvage Therapy
12/2009
1Blood Component Removal (Apheresis)
06/2008
1Subcutaneous Injections
04/2006
1Intravenous Infusions
04/2006