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Young C Lin Selected Research

Gossypol

3/2013(-)-Gossypol-enriched cottonseed oil inhibits proliferation and adipogenesis of human breast pre-adipocytes.
12/2011Liposomes containing (-)-gossypol-enriched cottonseed oil suppress Bcl-2 and Bcl-xL expression in breast cancer cells.
11/2010Leptin and zeranol up-regulate cyclin D1 expression in primary cultured normal human breast pre-adipocytes.
7/2010Induction of apoptosis by (-)-gossypol-enriched cottonseed oil in human breast cancer cells.
11/2009Mitogenic activity of zeranol in human breast cancer cells is enhanced by leptin and suppressed by gossypol.
7/2009Gossypol inhibits the growth of MAT-LyLu prostate cancer cells by modulation of TGFbeta/Akt signaling.
6/2009(-)-Gossypol reduces invasiveness in metastatic prostate cancer cells.
9/2008A liposomal delivery vehicle for the anticancer agent gossypol.
1/2007Modulation of multidrug resistance gene expression in human breast cancer cells by (-)-gossypol-enriched cottonseed oil.
9/2006Effects of serum on (-)-gossypol-suppressed growth in human prostate cancer cells.
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Young C Lin Research Topics

Disease

26Breast Neoplasms (Breast Cancer)
03/2013 - 01/2002
15Neoplasms (Cancer)
03/2013 - 11/2002
7Prostatic Neoplasms (Prostate Cancer)
07/2009 - 05/2002
3Lung Neoplasms (Lung Cancer)
01/2006 - 01/2002
2Obesity
12/2010 - 11/2009
1Atrophy
01/2013
1Neoplasm Metastasis (Metastasis)
01/2004

Drug/Important Bio-Agent (IBA)

14GossypolIBA
03/2013 - 01/2002
12ZeranolIBA
01/2013 - 01/2002
10Estrogens (Estrogen)FDA Link
04/2011 - 11/2002
8Messenger RNA (mRNA)IBA
12/2011 - 01/2002
7Cottonseed Oil (Cottonseed)IBA
12/2011 - 01/2004
4Protein Tyrosine PhosphatasesIBA
06/2010 - 01/2002
3LeptinIBA
11/2010 - 11/2009
3Estrogen Receptor alphaIBA
08/2009 - 01/2006
3TamoxifenFDA LinkGeneric
08/2009 - 05/2006
3Fibroblast Growth Factor 7FDA Link
08/2009 - 05/2006
3Linoleic Acid (Linoleate)IBA
01/2008 - 11/2005
3Estradiol (Estrace)FDA LinkGeneric
11/2004 - 11/2002
2Liposomes (Liposome)IBA
12/2011 - 09/2008
2Aromatase (CYP19)IBA
12/2010 - 05/2005
2Proteins (Proteins, Gene)IBA
06/2010 - 07/2009
2Cyclin D1IBA
07/2009 - 01/2004
2HormonesIBA
05/2006 - 05/2005
1Paclitaxel (Taxol)FDA LinkGeneric
12/2011
1Endocrine DisruptorsIBA
04/2011
1AdipokinesIBA
11/2010
1Class 5 Receptor-Like Protein Tyrosine PhosphatasesIBA
06/2010
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
08/2009
1Transforming Growth Factor beta (TGF-beta)IBA
07/2009
1P-GlycoproteinIBA
01/2007
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2007
1Charcoal (Charbon)IBA
09/2006
1Bovine Serum AlbuminIBA
09/2006
1Dextrans (Dextran)FDA Link
09/2006
1Blood Proteins (Serum Proteins)IBA
09/2006
1DNA (Deoxyribonucleic Acid)IBA
05/2006
1PeptidesIBA
05/2006
1Progesterone Receptors (Progesterone Receptor)IBA
05/2006
1Trypan BlueFDA Link
05/2006
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
05/2006
1Dinoprostone (PGE2)FDA Link
03/2006
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
03/2006
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2005
1Carbon MonoxideIBA
11/2005
1nimesulide (Aulin)IBA
05/2005
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
05/2005
1N- (2- cyclohexyloxy- 4- nitrophenyl)methanesulfonamideIBA
05/2005
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
05/2005
1Piroxicam (Feldene)FDA LinkGeneric
05/2005
1Niflumic AcidIBA
05/2005
1celecoxib (Celebrex)FDA Link
05/2005
1Indomethacin (Indometacin)FDA LinkGeneric
05/2005
11- ((4- methylsulfonyl)phenyl)- 3- trifluoromethyl- 5- (4- fluorophenyl)pyrazoleIBA
05/2005
1Enzyme InhibitorsIBA
05/2005
1Ibuprofen (Motrin)FDA LinkGeneric
05/2005
1Insulin-Like Growth Factor I (IGF-1)IBA
03/2005
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
02/2004
1Tyrosine (L-Tyrosine)FDA Link
02/2004
1AgarIBA
02/2004
1Transforming Growth Factor beta1 (TGF beta 1)IBA
01/2004
1ThymidineIBA
01/2004

Therapy/Procedure

3Mammaplasty (Breast Reconstruction)
01/2006 - 01/2002
1Heterologous Transplantation (Xenotransplantation)
12/2011
1Drug Therapy (Chemotherapy)
01/2007