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Ross L Levine Selected Research

Thrombopoietin Receptors

9/2012Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy.
4/2009The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model.
11/2007Advances in the molecular characterization of Philadelphia-negative chronic myeloproliferative disorders.
1/2007JAK-2 mutations and their relevance to myeloproliferative disease.

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Ross L Levine Research Topics

Disease

31Neoplasms (Cancer)
11/2015 - 12/2006
19Primary Myelofibrosis (Myelosclerosis)
03/2015 - 04/2005
16Polycythemia Vera
08/2013 - 04/2005
14Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2014 - 11/2006
11Leukemia
10/2015 - 10/2006
8Essential Thrombocythemia
08/2013 - 04/2005
8Thrombocytosis (Thrombocythemia)
05/2013 - 09/2005
7Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
11/2015 - 02/2012
6Myeloproliferative Disorders (Myeloproliferative Disorder)
02/2013 - 08/2005
5Fibrosis (Cirrhosis)
12/2015 - 06/2006
5Glioma (Gliomas)
03/2012 - 12/2006
4Myelodysplastic Syndromes (Myelodysplastic Syndrome)
09/2014 - 08/2005
3Splenomegaly
03/2015 - 06/2006
3BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
02/2011 - 11/2007
3Stroke (Strokes)
04/2009 - 01/2003
2Hairy Cell Leukemia
10/2015 - 05/2012
2Rheumatoid Arthritis
04/2014 - 06/2012
2Thrombosis (Thrombus)
10/2013 - 05/2013
2Polycythemia (Erythrocytosis)
02/2007 - 01/2006
2Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic)
11/2006 - 08/2005
2Hyperplasia
10/2006 - 06/2006
2Hypersensitivity (Allergy)
07/2006 - 06/2006
1Genomic Instability
10/2015
1Colitis
09/2015
1Inflammation
09/2015
1Shock
09/2015
1Melanoma (Melanoma, Malignant)
05/2014
1Hematologic Neoplasms (Hematological Malignancy)
11/2013
1B-Cell Lymphoma (Lymphoma, B Cell)
05/2013
1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
05/2013
1Hypercholesterolemia
05/2013
1Atherosclerosis
05/2013
1Acute Promyelocytic Leukemia
01/2013
1Mesothelioma
09/2012
1Hereditary Neoplastic Syndromes (Cancer Syndrome, Hereditary)
09/2012
1Psoriasis (Pustulosis Palmaris et Plantaris)
06/2012
1Chondrosarcoma
03/2012
1Oligodendroglioma
10/2010

Drug/Important Bio-Agent (IBA)

17Phosphotransferases (Kinase)IBA
12/2015 - 12/2006
13Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
05/2013 - 04/2005
6INCB018424IBA
12/2015 - 06/2013
6DNA (Deoxyribonucleic Acid)IBA
12/2014 - 08/2005
6Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
09/2013 - 03/2010
5alpha-hydroxyglutarateIBA
06/2013 - 03/2010
4Histones (Histone)IBA
11/2015 - 03/2012
4Thrombopoietin ReceptorsIBA
09/2012 - 01/2007
3Proteins (Proteins, Gene)IBA
09/2015 - 05/2013
3ErythropoietinFDA Link
02/2014 - 06/2006
3Janus Kinase 2IBA
02/2012 - 08/2005
3Reticulin (Reticular Fiber)IBA
10/2006 - 06/2006
2CytokinesIBA
12/2015 - 03/2015
2cohesins (cohesin)IBA
10/2015 - 09/2014
2ChromatinIBA
09/2015 - 11/2013
2Transcription Factors (Transcription Factor)IBA
09/2015 - 10/2013
2Carbon MonoxideIBA
09/2013 - 12/2006
2CholesterolIBA
05/2013 - 02/2013
2Cytokine Receptors (Cytokine Receptor)IBA
08/2012 - 02/2012
2Epidermal Growth Factor Receptor (EGF Receptor)IBA
10/2010 - 12/2006
2Tyrosine (L-Tyrosine)FDA Link
05/2008 - 11/2007
1Transforming Growth Factors (Transforming Growth Factor)IBA
12/2015
1Janus Kinase 1IBA
11/2015
1Lysine (L-Lysine)FDA Link
11/2015
1purineIBA
10/2015
1Dextran SulfateIBA
09/2015
1Interleukin-6 (Interleukin 6)IBA
09/2015
1Histone Deacetylase InhibitorsIBA
08/2014
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
05/2014
1Adenosine Triphosphate (ATP)IBA
04/2014
1cancer procoagulantIBA
10/2013
1Thromboplastin (Tissue Factor)IBA
10/2013
1InterferonsIBA
08/2013
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2013
1histone methyltransferaseIBA
05/2013
1InterleukinsIBA
05/2013
1RNA (Ribonucleic Acid)IBA
03/2013
1HDL CholesterolIBA
02/2013
1Glucose (Dextrose)FDA LinkGeneric
02/2013
1tebufenozide (Mimic)IBA
01/2013
1Prednisolone (Predate)FDA LinkGeneric
10/2012
1Uveal melanomaIBA
09/2012
1ubiquitin isopeptidaseIBA
09/2012
1Apolipoproteins E (ApoE)IBA
08/2012
1Arginine (L-Arginine)FDA Link
05/2012
1Serine (L-Serine)FDA Link
05/2012
1Complement System Proteins (Complement)IBA
05/2012
1PU H71IBA
10/2010
1Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
10/2010
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
10/2010
1Reactive Oxygen Species (Oxygen Radicals)IBA
04/2010
1INCB 16562IBA
04/2010

Therapy/Procedure

4Transplants (Transplant)
01/2007 - 06/2006
3Bone Marrow Transplantation (Transplantation, Bone Marrow)
02/2007 - 01/2006
2Transplantation (Transplant Recipients)
05/2013 - 04/2013
2Stents
11/2007 - 08/2007
1Aftercare (After-Treatment)
10/2015
1Drug Therapy (Chemotherapy)
02/2014
1Molecular Targeted Therapy
05/2013
1Retreatment
03/2013
1Investigational Therapies (Experimental Therapy)
11/2012
1Immunotherapy
05/2012