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Tsukasa Koyama Selected Research

Serotonin Uptake Inhibitors (Serotonin Reuptake Inhibitors)

1/2015Efficacy comparison of duloxetine and SSRIs at doses approved in Japan.
10/2014Local infusion of citalopram into the basolateral amygdala decreased conditioned fear of rats through increasing extracellular serotonin levels.
1/2014Effect of the coadministration of citalopram with mirtazapine or atipamezole on rat contextual conditioned fear.
4/20135-HT depletion, but not 5-HT1A antagonist, prevents the anxiolytic-like effect of citalopram in rat contextual conditioned fear stress model.
8/2012Sertraline treatment of patients with major depressive disorder who failed initial treatment with paroxetine or fluvoxamine.
2/2012[Anxiety disorder].
4/2007Fluvoxamine treatment of generalized social anxiety disorder in Japan: a randomized double-blind, placebo-controlled study.
8/2004Selective serotonin reuptake inhibitor reduces conditioned fear through its effect in the amygdala.
6/2004[Biological basis of anxiety disorders and serotonergic anxiolytics].

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Tsukasa Koyama Research Topics

Disease

21Schizophrenia (Dementia Praecox)
01/2015 - 10/2002
13Bipolar Disorder (Mania)
03/2013 - 06/2003
10Major Depressive Disorder (Major Depressive Disorders)
01/2015 - 06/2003
10Anxiety Disorders (Anxiety Disorder)
10/2014 - 06/2004
5Mood Disorders (Mood Disorder)
12/2007 - 04/2002
4Weight Gain
03/2012 - 01/2005
3Delirium
01/2012 - 11/2003
2Body Weight (Weight, Body)
01/2015 - 03/2012
2Depressive Disorder (Melancholia)
10/2014 - 03/2011
2Shock
01/2014 - 09/2005
2Psychomotor Agitation (Akathisia)
12/2013 - 02/2005
2Dyslipidemias (Dyslipidemia)
03/2012 - 12/2011
2Mental Disorders (Mental Disorder)
01/2012 - 04/2002
2Diabetes Mellitus
12/2011 - 02/2007
2Hyperglycemia
06/2011 - 08/2007
2Sleep Initiation and Maintenance Disorders (Insomnia)
05/2011 - 01/2007
1Dystonia (Limb Dystonia)
04/2012
1Body Weight Changes
03/2012
1Teratoma (Teratoid Tumor)
01/2009
1Encephalitis (Encephalitis, Rasmussen)
01/2009
1Parkinson Disease (Parkinson's Disease)
04/2008
1Epilepsy (Aura)
06/2007
1Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
04/2007
1Obesity
02/2007
1Insulin Resistance
02/2007

Drug/Important Bio-Agent (IBA)

11Antipsychotic Agents (Antipsychotics)IBA
01/2015 - 11/2003
9Serotonin Uptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
01/2015 - 06/2004
8Serotonin (5 Hydroxytryptamine)IBA
02/2012 - 06/2003
6CalciumIBA
01/2012 - 06/2003
6N-Methylaspartate (NMDA)IBA
10/2011 - 05/2007
6LithiumIBA
03/2011 - 01/2004
4Paroxetine (Paxil)FDA LinkGeneric
01/2015 - 01/2007
4Risperidone (Risperdal Consta)FDA LinkGeneric
03/2011 - 11/2005
4Dizocilpine Maleate (Dizocilpine)IBA
01/2011 - 05/2007
3quetiapine (Seroquel)FDA Link
01/2015 - 11/2003
3aripiprazole (Abilify)FDA Link
12/2013 - 01/2011
3Valproic Acid (Valproate, Semisodium)FDA LinkGeneric
03/2013 - 01/2004
3milnacipran (Ixel)FDA Link
01/2013 - 09/2003
3Fluvoxamine (Luvox)FDA LinkGeneric
08/2012 - 01/2007
3olanzapine (Zyprexa)FDA Link
03/2012 - 01/2005
3Blood Glucose (Blood Sugar)IBA
03/2012 - 02/2007
3Carbon MonoxideIBA
03/2011 - 01/2007
3Methamphetamine (Desoxyn)FDA LinkGeneric
01/2011 - 05/2007
3GhrelinIBA
08/2007 - 01/2005
3Dopamine (Intropin)FDA LinkGeneric
05/2007 - 09/2003
2ProlactinIBA
01/2015 - 02/2007
2Citalopram (Escitalopram)FDA Link
01/2015 - 01/2014
2mirtazapine (Rexer)FDA LinkGeneric
01/2014 - 05/2009
2CholesterolIBA
03/2012 - 02/2007
2Hemoglobins (Hemoglobin)IBA
03/2012 - 02/2007
2TabletsIBA
03/2012 - 03/2011
2Anti-Anxiety Agents (Anxiolytics)IBA
02/2012 - 06/2004
2Biological Markers (Surrogate Marker)IBA
01/2012 - 10/2004
2Glucose (Dextrose)FDA LinkGeneric
06/2011 - 02/2007
2BenzodiazepinesIBA
05/2011 - 02/2005
2Haloperidol (Haldol)FDA LinkGeneric
01/2011 - 09/2005
2Glutamic Acid (Glutamate)FDA Link
01/2011 - 04/2008
2Antidepressive Agents (Antidepressants)IBA
12/2010 - 01/2007
2Dopamine Agonists (Dopamine Agonist)IBA
04/2008 - 09/2003
2Dopamine D2 Receptors (Dopamine D2 Receptor)IBA
02/2008 - 05/2007
2perospironeIBA
02/2008 - 02/2005
2Clozapine (Clozaril)FDA LinkGeneric
08/2007 - 01/2006
2ThrombinFDA Link
01/2004 - 10/2002
25-HT2A Serotonin Receptor (5 HT2A Receptor)IBA
06/2003 - 04/2002
1duloxetine (Cymbalta)FDA Link
01/2015
1Cytochrome P-450 CYP2D6 (CYP2D6)IBA
12/2013
1dystrobrevinIBA
08/2013
1Carrier Proteins (Binding Protein)IBA
08/2013
1Glycine (Aminoacetic Acid)FDA LinkGeneric
08/2013
1Selegiline (E250)FDA LinkGeneric
01/2013
1Monoamine Oxidase (MAO)IBA
01/2013
1Sertraline (Zoloft)FDA LinkGeneric
08/2012
1Triglycerides (Triacylglycerol)IBA
03/2012
1HDL CholesterolIBA
03/2012
1Propranolol (Inderal)FDA LinkGeneric
02/2012
1Neurotransmitter Agents (Neurotransmitter)IBA
02/2012
1Cycloserine (Seromycin)FDA Link
02/2012
1Dopamine Receptors (Dopamine Receptor)IBA
01/2012
1Bromisovalum (Bromisoval)IBA
05/2011
1gabapentin (Neurontin)FDA LinkGeneric
05/2011
1lamotrigine (Lamictal)FDA LinkGeneric
03/2011
1pramipexol (pramipexole)FDA LinkGeneric
12/2010
1gamma-Globulins (gamma-Globulin)IBA
01/2009
1alpha Adrenergic ReceptorsIBA
08/2007
1Lennox-Gastaut type Epileptic encephalopathyIBA
06/2007
1gamma-Aminobutyric Acid (GABA)IBA
06/2007
1tandospironeIBA
05/2007
1Norepinephrine (Noradrenaline)FDA LinkGeneric
04/2007
1atomoxetine (Strattera)FDA LinkGeneric
04/2007
1Methylphenidate (Ritalin)FDA LinkGeneric
04/2007
1Amphetamine (Amfetamine)FDA LinkGeneric
04/2007
1Lipoproteins (Lipoprotein)IBA
02/2007
1LDL CholesterolIBA
02/2007
1AdiponectinIBA
02/2007
1Insulin (Novolin)FDA Link
02/2007
1LeptinIBA
02/2007
1ThapsigarginIBA
01/2007
1Protein Kinase CIBA
01/2007

Therapy/Procedure

1Injections
01/2014
1Therapeutics
05/2011