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Jan Koster Selected Research

N(1)-guanyl-1,7-diaminoheptane

12/2014Deoxyhypusine synthase (DHPS) inhibitor GC7 induces p21/Rb-mediated inhibition of tumor cell growth and DHPS expression correlates with poor prognosis in neuroblastoma patients.

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Jan Koster Research Topics

Disease

35Neuroblastoma
08/2015 - 04/2006
34Neoplasms (Cancer)
11/2015 - 04/2006
9Medulloblastoma
07/2014 - 01/2008
3Neoplasm Metastasis (Metastasis)
06/2015 - 02/2013
3Colorectal Neoplasms (Colorectal Cancer)
06/2015 - 04/2008
3Ganglioneuroma
05/2009 - 04/2008
3Bullous Pemphigoid (Pemphigoid)
01/2004 - 01/2003
2Residual Neoplasm
01/2015 - 10/2012
2Brain Neoplasms (Brain Tumor)
08/2013 - 07/2012
1Anoxia (Hypoxia)
09/2015
1Colonic Neoplasms (Colon Cancer)
06/2015
1Wilms Tumor (Wilm's Tumor)
02/2015
1Disease Progression
01/2015
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell)
11/2014
1Marginal Zone B-Cell Lymphoma (MALT Lymphoma)
11/2014
1Lymphoma (Lymphomas)
11/2014
1Tics (Tic)
02/2014
1Breast Neoplasms (Breast Cancer)
01/2014
1Genomic Instability
08/2013
1Astrocytoma (Pilocytic Astrocytoma)
08/2013
1Chromosomal Instability (Chromosome Stability)
08/2013
1Rhabdoid Tumor (Rhabdoid Tumors)
12/2012
1Glioma (Gliomas)
07/2010
1Ganglioneuroblastoma
05/2009
1Adenoma (Adenomas)
04/2008
1Blepharophimosis
01/2008
1Prostatic Neoplasms (Prostate Cancer)
10/2007
1Junctional Epidermolysis Bullosa (Epidermolysis Bullosa Letalis)
01/2004

Drug/Important Bio-Agent (IBA)

18Messenger RNA (mRNA)IBA
11/2015 - 04/2006
8Transcription Factors (Transcription Factor)IBA
11/2014 - 02/2008
5MicroRNAs (MicroRNA)IBA
02/2015 - 11/2012
4RNA (Ribonucleic Acid)IBA
11/2015 - 08/2012
4Small Interfering RNA (siRNA)IBA
06/2015 - 07/2012
4Carbon MonoxideIBA
01/2014 - 01/2008
3Phosphotransferases (Kinase)IBA
07/2015 - 04/2008
3Histones (Histone)IBA
06/2015 - 03/2009
3beta CateninIBA
04/2008 - 01/2008
3AntigensIBA
01/2004 - 01/2003
2Histone DemethylasesIBA
06/2015 - 03/2009
2sepiapterin reductaseIBA
01/2015 - 01/2014
2DNA (Deoxyribonucleic Acid)IBA
01/2015 - 05/2011
2Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA
01/2014 - 05/2010
2Lysine (L-Lysine)FDA Link
03/2013 - 03/2009
2Otx Transcription FactorsIBA
03/2013 - 07/2012
2Tretinoin (Retinoic Acid)FDA LinkGeneric
07/2010 - 04/2009
2ChromatinIBA
03/2009 - 04/2008
1tetraethylpyrazine (TEP)IBA
11/2015
1Conditioned Culture MediaIBA
09/2015
1Stem Cell FactorIBA
09/2015
1AgarIBA
07/2015
1Complement System Proteins (Complement)IBA
05/2015
1Sulfasalazine (Azulfidine)FDA LinkGeneric
01/2015
1SpermidineIBA
12/2014
1N(1)-guanyl-1,7-diaminoheptaneIBA
12/2014
1deoxyhypusine synthaseIBA
12/2014
1OxygenIBA
11/2014
1Serum-Free Culture MediaIBA
02/2014
1Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA
02/2014
15,6,7,8-tetrahydrobiopterin (tetrahydrobiopterin)FDA Link
01/2014
1Proteins (Proteins, Gene)IBA
01/2014
1Nitric Oxide Synthase (NO Synthase)IBA
01/2014
1Adenocarcinoma of lungIBA
01/2014
1Protein Kinases (Protein Kinase)IBA
08/2013
1Small Nucleolar RibonucleoproteinsIBA
08/2013
1Telomerase (Telomerase Reverse Transcriptase)IBA
08/2013
1PI103IBA
04/2013
1Biological Markers (Surrogate Marker)IBA
04/2013
1Cyclin-Dependent Kinase Inhibitor p27IBA
04/2013
1Eflornithine (Ornidyl)FDA Link
04/2013
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
02/2013
1Tyrosine (L-Tyrosine)FDA Link
02/2013
1Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)IBA
02/2013
1ABT 263IBA
11/2012
1Doxycycline (Vibramycin)FDA LinkGeneric
10/2010
1Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
06/2010
1LigandsIBA
03/2010
1roscovitineIBA
08/2009
1Nerve Growth Factor Receptors (Neurotrophin Receptors)IBA
05/2009
1Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)IBA
05/2009
1RetinoidsIBA
04/2009
1Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)IBA
03/2009
1Cyclin D1IBA
04/2008
1A-Form DNA (A-DNA)IBA
04/2008
1NBPhox proteinIBA
02/2008
1CeruleninIBA
11/2007
1Annexin A5IBA
11/2007
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
11/2007
1Carrier Proteins (Binding Protein)IBA
10/2007
1CollagenIBA
01/2004
1Recombinant ProteinsIBA
06/2003
1Amino AcidsFDA Link
06/2003
1PlectinIBA
01/2003

Therapy/Procedure

9Heterologous Transplantation (Xenotransplantation)
09/2015 - 03/2009
4Drug Therapy (Chemotherapy)
08/2015 - 07/2014
3Therapeutics
10/2012 - 08/2009
2Combined Modality Therapy
01/2015 - 12/2014