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Per Kogner Selected Research

Neuroblastoma

6/2015COX/mPGES-1/PGE2 pathway depicts an inflammatory-dependent high-risk neuroblastoma subset.
2/2015Intragenic anaplastic lymphoma kinase (ALK) rearrangements: translocations as a novel mechanism of ALK activation in neuroblastoma tumors.
11/2014The risk-associated long noncoding RNA NBAT-1 controls neuroblastoma progression by regulating cell proliferation and neuronal differentiation.
9/2014Emergence of new ALK mutations at relapse of neuroblastoma.
4/2014RNA helicase A is a downstream mediator of KIF1Bβ tumor-suppressor function in neuroblastoma.
3/2014Protective role of humanin on bortezomib-induced bone growth impairment in anticancer treatment.
11/2013Frequent detection of human cytomegalovirus in neuroblastoma: a novel therapeutic target?
9/2013Dual targeting of wild-type and mutant p53 by small molecule RITA results in the inhibition of N-Myc and key survival oncogenes and kills neuroblastoma cells in vivo and in vitro.
6/2013MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells.
5/2013Low-dose aspirin delays an inflammatory tumor progression in vivo in a transgenic mouse model of neuroblastoma.
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Per Kogner Research Topics

Disease

52Neuroblastoma
06/2015 - 01/2003
38Neoplasms (Cancer)
06/2015 - 02/2002
6Medulloblastoma
03/2014 - 10/2008
3Inflammation
06/2015 - 01/2012
3Residual Neoplasm
11/2011 - 04/2003
3Brain Neoplasms (Brain Tumor)
01/2010 - 02/2002
2Lung Neoplasms (Lung Cancer)
02/2015 - 11/2009
2Pheochromocytoma
04/2014 - 03/2007
2Ganglioneuroma
01/2007 - 01/2006
2Necrosis
10/2005 - 12/2004
1Lymphoma (Lymphomas)
02/2015
1Teratoma (Teratoid Tumor)
04/2014
1Neuroectodermal Tumors (Neuroectodermal Tumor)
04/2014
1Chromosome Aberrations (Chromosome Abnormalities)
01/2012
1Disease Progression
01/2011
1Infection
07/2010
1Neutropenia
07/2010

Drug/Important Bio-Agent (IBA)

11DNA (Deoxyribonucleic Acid)IBA
11/2013 - 04/2003
9Messenger RNA (mRNA)IBA
02/2013 - 01/2003
7Proteins (Proteins, Gene)IBA
02/2015 - 08/2004
5Phosphotransferases (Kinase)IBA
09/2014 - 01/2010
4Dinoprostone (PGE2)FDA Link
06/2015 - 10/2008
4Diclofenac (SR 38)FDA LinkGeneric
06/2015 - 10/2004
4anaplastic lymphoma kinaseIBA
02/2015 - 12/2008
4Cyclooxygenase 2 (Cyclooxygenase-2)IBA
01/2012 - 10/2004
4celecoxib (Celebrex)FDA Link
10/2011 - 10/2004
4Choline (Choline Chloride)IBA
10/2005 - 10/2004
4Protons (Proton)IBA
10/2005 - 10/2004
3prostaglandin-E synthaseIBA
06/2015 - 10/2008
3Prostaglandins E (PGE)IBA
01/2012 - 10/2008
3Cisplatin (Platino)FDA LinkGeneric
07/2010 - 10/2004
3Doxorubicin (Adriamycin)FDA LinkGeneric
03/2009 - 05/2006
3Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
12/2008 - 01/2003
3Arachidonic Acid (Vitamin F)IBA
10/2008 - 10/2004
3irinotecan (Camptosar)FDA LinkGeneric
02/2007 - 10/2004
3Galanin Receptors (Galanin Receptor)IBA
01/2006 - 02/2002
3GalaninIBA
01/2006 - 02/2002
3Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
10/2005 - 10/2004
3Tretinoin (Retinoic Acid)FDA LinkGeneric
11/2003 - 04/2003
2EnzymesIBA
06/2015 - 10/2008
2Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
06/2015 - 03/2009
2tyrosine receptor (receptor, tyrosine)IBA
09/2014 - 03/2013
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
04/2014 - 08/2009
2RNA (Ribonucleic Acid)IBA
11/2013 - 10/2011
2Carbon MonoxideIBA
09/2013 - 06/2005
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2011 - 08/2009
2Arachidonate 15-Lipoxygenase (Arachidonate 15 Lipoxygenase)IBA
04/2011 - 03/2010
2trichostatin A (A 300)IBA
01/2011 - 07/2008
2Etoposide (VP 16)FDA LinkGeneric
07/2010 - 10/2004
2Small Interfering RNA (siRNA)IBA
11/2009 - 10/2008
2Caspase 8 (Caspase-8)IBA
05/2008 - 12/2004
2PeptidesIBA
08/2006 - 06/2005
2Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
10/2005 - 10/2005
2NeuropeptidesIBA
06/2005 - 02/2002
2RetinoidsIBA
11/2003 - 04/2003
1VimentinIBA
06/2015
1temozolomide (Temodar)FDA LinkGeneric
01/2015
1Untranslated RNA (Noncoding RNA)IBA
11/2014
1KinesinIBA
04/2014
1Nerve Growth Factor (NGF)IBA
04/2014
1Complement System Proteins (Complement)IBA
04/2014
1RNA Helicases (RNA Helicase)IBA
04/2014
1Proteasome Endopeptidase Complex (Proteasome)IBA
03/2014
1bortezomib (Velcade)FDA Link
03/2014
1Tissue ExtractsIBA
11/2013
1aurora kinase (aurora A kinase)IBA
09/2013
1Thromboxane A2 (A2, Thromboxane)IBA
05/2013
1Transforming Growth Factors (Transforming Growth Factor)IBA
05/2013
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
05/2013
1Prostaglandin D2IBA
05/2013
1GANT 61IBA
04/2013
1cyclopamineIBA
04/2013
1Cyclin D1IBA
04/2013
1Protein Isoforms (Isoforms)IBA
01/2013
1Cyclic AMP (AMP, Cyclic)IBA
01/2012
1CalciumIBA
01/2012
1PI103IBA
12/2011
1Immediate-Early ProteinsIBA
10/2011
1valganciclovirFDA Link
10/2011
1Culture MediaIBA
07/2011
1tebufenozide (Mimic)IBA
07/2011
1MicroRNAs (MicroRNA)IBA
07/2011
1docosahexaenoylascorbic acid (DHA-As)IBA
04/2011
1decitabine (5-aza-2'-deoxycytidine)FDA Link
01/2011
1alpha 2(I) collagenIBA
01/2011
1Serine (L-Serine)FDA Link
01/2011
1Histone Deacetylase InhibitorsIBA
01/2011
1Retinoblastoma ProteinIBA
11/2010
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
07/2010
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
07/2010
1Vincristine (Oncovin)FDA LinkGeneric
07/2010
1Carboplatin (JM8)FDA LinkGeneric
07/2010
1Filgrastim (Neupogen)FDA Link
07/2010
1Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
05/2010

Therapy/Procedure

18Heterologous Transplantation (Xenotransplantation)
04/2014 - 03/2003
6Drug Therapy (Chemotherapy)
07/2010 - 10/2004
2Injections
03/2014 - 08/2006
2Immunotherapy
03/2008 - 11/2003
1Transplantation (Transplant Recipients)
04/2014
1Combined Modality Therapy
01/2013