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Patrick M Kochanek Selected Research

Phosphopyruvate Hydratase (Enolase)

3/2014Serum biomarkers of brain injury to classify outcome after pediatric cardiac arrest*.
4/2008Biomarkers of primary and evolving damage in traumatic and ischemic brain injury: diagnosis, prognosis, probing mechanisms, and therapeutic decision making.
1/2007Cerebrospinal fluid biomarkers versus glasgow coma scale and glasgow outcome scale in pediatric traumatic brain injury: the role of young age and inflicted injury.
1/2006Serum biomarkers after traumatic and hypoxemic brain injuries: insight into the biochemical response of the pediatric brain to inflicted brain injury.
7/2005Serum neuron-specific enolase, S100B, and myelin basic protein concentrations after inflicted and noninflicted traumatic brain injury in children.
9/2004Continuous versus intermittent cerebrospinal fluid drainage after severe traumatic brain injury in children: effect on biochemical markers.
8/2003F2-isoprostane and neuron-specific enolase in cerebrospinal fluid after severe traumatic brain injury in infants and children.
2/2002Neuron-specific enolase and S100B in cerebrospinal fluid after severe traumatic brain injury in infants and children.

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Patrick M Kochanek Research Topics

Disease

93Brain Injuries (Brain Injury)
07/2015 - 01/2002
52Hypothermia
05/2015 - 01/2002
44Heart Arrest (Cardiac Arrest)
11/2015 - 01/2002
11Ischemia
09/2015 - 05/2002
10Exsanguination
04/2012 - 04/2006
9Wounds and Injuries (Trauma)
06/2014 - 01/2002
8Neurologic Manifestations (Neurological Manifestations)
11/2015 - 01/2002
8Hemorrhagic Shock
09/2013 - 10/2002
7Ventricular Fibrillation
08/2015 - 10/2004
7Craniocerebral Trauma (Head Injury)
07/2015 - 01/2002
7Asphyxia (Suffocation)
02/2015 - 02/2003
6Hemorrhage
07/2015 - 04/2006
5Seizures (Seizure)
08/2015 - 03/2004
5Inflammation
07/2015 - 09/2004
5Anoxia (Hypoxia)
02/2014 - 03/2004
5Coma (Comas)
01/2014 - 05/2003
4Intracranial Hypertension
05/2015 - 07/2003
4Brain Ischemia (Cerebral Ischemia)
02/2015 - 09/2004
3Critical Illness (Critically Ill)
09/2015 - 04/2012
3Epilepsy (Aura)
08/2015 - 04/2006
3Drowning
05/2015 - 12/2012
3Hyperoxia
02/2014 - 09/2009
3Alzheimer Disease (Alzheimer's Disease)
06/2013 - 12/2002
3Shock
06/2013 - 06/2011
3Fever (Fevers)
12/2012 - 02/2003
3Central Nervous System Diseases (CNS Diseases)
12/2012 - 09/2004
2Edema
11/2015 - 02/2014
2Hypertension (High Blood Pressure)
08/2015 - 12/2014
2Brain Edema (Cerebral Edema)
02/2015 - 09/2013
2Mitochondrial Diseases (Mitochondrial Disease)
11/2014 - 08/2014
2Stroke (Strokes)
08/2014 - 12/2006
2Hyperemia
06/2013 - 03/2012
2Hyperglycemia
01/2012 - 01/2010
2Hypoglycemia (Reactive Hypoglycemia)
01/2012 - 01/2010
2Status Epilepticus (Complex Partial Status Epilepticus)
05/2010 - 04/2006
2Infection
03/2010 - 01/2010
2Starvation
01/2009 - 03/2008

Drug/Important Bio-Agent (IBA)

12Biological Markers (Surrogate Marker)IBA
07/2015 - 07/2004
10salicylhydroxamic acid (SHAM)IBA
09/2015 - 05/2002
9Glucose (Dextrose)FDA LinkGeneric
11/2014 - 05/2002
9OxygenIBA
02/2014 - 02/2008
8AdenosineFDA LinkGeneric
08/2015 - 03/2004
8Phosphopyruvate Hydratase (Enolase)IBA
03/2014 - 02/2002
7IsofluraneFDA LinkGeneric
09/2009 - 05/2002
6Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
11/2015 - 03/2006
6IceIBA
03/2015 - 08/2005
6Proteins (Proteins, Gene)IBA
01/2013 - 01/2006
5Cytochromes c (Cytochrome c)IBA
07/2012 - 07/2005
4EnzymesIBA
08/2015 - 08/2004
4CytokinesIBA
03/2015 - 03/2004
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2015 - 01/2003
4Interleukin-6 (Interleukin 6)IBA
01/2014 - 01/2003
4Fentanyl (Sublimaze)FDA LinkGeneric
04/2012 - 04/2003
4Reactive Oxygen Species (Oxygen Radicals)IBA
03/2012 - 05/2004
4Adenosine Diphosphate (ADP)IBA
11/2008 - 05/2003
320-hydroxy-5,8,11,14-eicosatetraenoic acidIBA
11/2015 - 12/2006
3Cardiolipins (Cardiolipin)IBA
02/2015 - 08/2007
3Propofol (Diprivan)FDA LinkGeneric
11/2014 - 01/2006
3Minocycline (Cyclops)FDA LinkGeneric
02/2014 - 09/2009
3Epinephrine (Adrenaline)FDA LinkGeneric
09/2013 - 06/2008
3Midazolam (Versed)FDA LinkGeneric
04/2012 - 05/2010
3CytochromesIBA
04/2012 - 03/2006
3Adenosine A1 ReceptorIBA
08/2010 - 04/2006
3Anesthetics (Anesthetic Agents)IBA
04/2009 - 04/2003
3F2-Isoprostanes (F2 Isoprostanes)IBA
02/2009 - 08/2003
3diazonaphthalenedisulfonic acid (NDS)IBA
11/2008 - 05/2003
3Nerve Growth Factor (NGF)IBA
02/2007 - 05/2004
3Glutamic Acid (Glutamate)FDA Link
02/2004 - 05/2002
2Small Interfering RNA (siRNA)IBA
09/2015 - 01/2009
2InterleukinsIBA
03/2015 - 01/2014
2Fatty Acids (Saturated Fatty Acids)IBA
02/2015 - 01/2009
2Hemoglobins (Hemoglobin)IBA
09/2013 - 03/2011
2HeliumIBA
06/2013 - 06/2011
2SilverIBA
06/2013 - 06/2011
2Amyloid (Amyloid Fibrils)IBA
06/2013 - 12/2002
2Nitric Oxide (Nitrogen Monoxide)FDA Link
05/2013 - 01/2003
2Cytochrome P-450 CYP3AIBA
04/2012 - 12/2011
2polynitroxyl-albuminIBA
03/2012 - 02/2011
2Blood Glucose (Blood Sugar)IBA
01/2012 - 01/2003
2ChlorzoxazoneFDA LinkGeneric
12/2011 - 03/2006
2Glutathione (Reduced Glutathione)IBA
02/2011 - 09/2004
23-nitrotyrosineIBA
02/2011 - 04/2007
2Superoxide DismutaseIBA
02/2011 - 04/2007
2Morphine (MS Contin)FDA LinkGeneric
12/2009 - 01/2006
2Cytochrome P-450 CYP2E1 (CYP2E1)IBA
01/2009 - 03/2006
2Cyclooxygenase 2 (Cyclooxygenase-2)IBA
12/2008 - 06/2006
2Poly Adenosine Diphosphate RiboseIBA
09/2008 - 05/2003

Therapy/Procedure

43Resuscitation
09/2015 - 10/2002
11Cardiopulmonary Bypass (Heart-Lung Bypass)
09/2013 - 01/2002
9Cardiopulmonary Resuscitation (CPR)
03/2015 - 04/2006
8Intensive Care (Surgical Intensive Care)
01/2014 - 01/2002
7Induced Hypothermia
09/2013 - 03/2005
5Rewarming
10/2013 - 04/2003
5Anesthesia
09/2009 - 04/2003
4Decompressive Craniectomy
11/2008 - 01/2003
3Catheters
09/2013 - 01/2002
3Induced Heart Arrest (Cardioplegia)
06/2010 - 03/2005
2Drug Therapy (Chemotherapy)
01/2014 - 04/2012
2Extracorporeal Membrane Oxygenation (ECMO)
01/2013 - 12/2009
2Critical Care
03/2010 - 09/2007