Tad H Koch Selected Research

Formaldehyde (Formol)

12/2004	Antiestrogen binding site and estrogen receptor mediate uptake and distribution of 4-hydroxytamoxifen-targeted doxorubicin-formaldehyde conjugate in breast cancer cells.
11/2004	Studies of targeting and intracellular trafficking of an anti-androgen doxorubicin-formaldehyde conjugate in PC-3 prostate cancer cells bearing androgen receptor-GFP chimera.
02/2004	Design, synthesis, and biological evaluation of doxorubicin-formaldehyde conjugates targeted to breast cancer cells.
11/2003	Rational design and synthesis of androgen receptor-targeted nonsteroidal anti-androgen ligands for the tumor-specific delivery of a doxorubicin-formaldehyde conjugate.

3	Breast Neoplasms (Breast Cancer) 12/2004 - 06/2002
1	Prostatic Neoplasms (Prostate Cancer) 11/2004
1	Neoplasms (Cancer) 11/2003
1	Carcinoma (Carcinomatosis) 01/2002

4	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2004 - 11/2003
4	Formaldehyde (Formol)IBA 12/2004 - 11/2003
2	Androgen Receptors (Androgen Receptor)IBA 11/2004 - 11/2003
1	Estrogens (Estrogen)FDA Link 12/2004
1	Estrogen Receptor Modulators (Antiestrogen)IBA 12/2004
1	LigandsIBA 11/2003
1	Acrolein (Aqualin)IBA 06/2002
1	epidoxoformIBA 01/2002