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Susumu Kobayashi Selected Research

Phosphatidic Acids (Phosphatidic Acid)

1/2007Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid.
8/2006Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis.
6/2004Attenuation by cyclic phosphatidic acid of peritoneal metastasis of azoxymethane-induced intestinal cancers in Wistar rats.
6/2003Cyclic phosphatidic acid inhibits RhoA-mediated autophosphorylation of FAK at Tyr-397 and subsequent tumor-cell invasion.

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Susumu Kobayashi Research Topics

Disease

33Neoplasms (Cancer)
01/2015 - 04/2002
21Lung Neoplasms (Lung Cancer)
01/2014 - 08/2005
18Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2014 - 02/2005
10Neoplasm Metastasis (Metastasis)
01/2012 - 05/2002
6Colorectal Neoplasms (Colorectal Cancer)
10/2012 - 06/2002
5Rectal Neoplasms (Rectal Cancer)
01/2012 - 01/2006
5Neuroblastoma
05/2008 - 03/2002
4Shock
11/2013 - 06/2002
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
11/2012 - 01/2002
4Melanoma (Melanoma, Malignant)
12/2010 - 06/2003
3Pain (Aches)
06/2013 - 03/2003
3Carcinoma (Carcinomatosis)
09/2010 - 04/2002
3Breast Neoplasms (Breast Cancer)
07/2010 - 01/2008
3B-Cell Leukemia (Leukemia, B Cell)
05/2008 - 03/2002
3Hepatocellular Carcinoma (Hepatoma)
12/2007 - 12/2002
2Hyperglycemia
02/2013 - 11/2012
2Parkinson Disease (Parkinson's Disease)
01/2011 - 05/2008
2Adenocarcinoma
07/2010 - 06/2004
2Anastomotic Leak
01/2010 - 05/2008
2Abscess
05/2008 - 01/2007
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
09/2007 - 04/2006
2Dehydration (Water Stress)
03/2007 - 03/2007
1Fatty Liver
11/2014
1Gaucher Disease (Gaucher's Disease)
11/2013
1Fanconi Anemia (Fanconi's Anemia)
11/2012
1Circulating Neoplastic Cells
10/2012
1Constipation
01/2012
1Lymphoma (Lymphomas)
01/2012
1Experimental Melanoma
05/2011
1Crohn Disease (Crohn's Disease)
09/2010
1Prostatic Neoplasms (Prostate Cancer)
07/2010
1Polycythemia Vera
04/2010

Drug/Important Bio-Agent (IBA)

19Epidermal Growth Factor Receptor (EGF Receptor)IBA
01/2013 - 02/2005
15Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2014 - 08/2005
14gefitinib (Iressa)FDA Link
02/2011 - 02/2005
11erlotinib (CP 358,774)FDA Link
07/2010 - 08/2005
5Thymidine PhosphorylaseIBA
11/2008 - 01/2002
5epolactaeneIBA
05/2008 - 03/2002
4Phosphatidic Acids (Phosphatidic Acid)IBA
01/2007 - 06/2003
3HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
11/2013 - 06/2002
3heat shock transcription factor (heat shock transcription factors)IBA
11/2013 - 06/2002
3SodiumIBA
06/2013 - 11/2012
3Carbon MonoxideIBA
02/2013 - 01/2002
3DNA (Deoxyribonucleic Acid)IBA
11/2012 - 06/2002
3Phosphotransferases (Kinase)IBA
07/2009 - 06/2006
2CholesterolIBA
11/2013 - 04/2012
2Glucose (Dextrose)FDA LinkGeneric
02/2013 - 11/2012
2Cisplatin (Platino)FDA LinkGeneric
11/2012 - 01/2008
2Transcription Factors (Transcription Factor)IBA
07/2012 - 09/2007
2Protein Kinases (Protein Kinase)IBA
04/2012 - 04/2010
21-Methyl-4-phenylpyridinium (1 Methyl 4 phenylpyridinium)IBA
01/2011 - 05/2008
2Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA
09/2010 - 03/2008
2Thymidylate SynthaseIBA
09/2010 - 03/2008
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2009 - 01/2006
2AntigensIBA
10/2007 - 01/2007
23-hydroxybutanal (aldol)IBA
03/2007 - 03/2007
2cetuximab (Erbitux)FDA Link
06/2006 - 08/2005
2Proteins (Proteins, Gene)IBA
04/2006 - 06/2003
2DNA-Directed DNA Polymerase (Polymerases, DNA)IBA
05/2005 - 05/2004
2lysophosphatidic acid (MOPA)IBA
06/2004 - 06/2003
2cholesteryl glucosideIBA
06/2003 - 06/2002
1RoxithromycinIBA
01/2015
1VLCAD deficiencyIBA
11/2014
1fosphenytoin (Cerebyx)FDA LinkGeneric
06/2013
1Phenytoin (Dilantin)FDA LinkGeneric
06/2013
1Doxorubicin (Adriamycin)FDA LinkGeneric
11/2012
1Messenger RNA (mRNA)IBA
07/2012
1Hydroxymethylglutaryl CoA Reductases (HMG CoA Reductase)IBA
04/2012
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
04/2012
1Coenzyme A (CoA)IBA
04/2012
1ATP Citrate (pro-S)-Lyase (Citrate Synthase, ATP)IBA
04/2012
1gimeracilIBA
01/2012
1PotassiumIBA
01/2012
1Oxonic AcidIBA
01/2012
1TegafurIBA
01/2012
1GadoliniumIBA
01/2012
1ceramide glucosyltransferaseIBA
05/2011
1Etoposide (VP 16)FDA LinkGeneric
01/2011
1Type II DNA Topoisomerases (Topoisomerase II)IBA
01/2011
1indoleIBA
01/2011
1neoechinulin AIBA
01/2011
1alkylglycerophosphoethanolamine phosphodiesteraseIBA
12/2010
1AntibodiesIBA
10/2010
1Fluorouracil (Carac)FDA LinkGeneric
09/2010
1coactivator-associated arginine methyltransferase 1IBA
07/2010

Therapy/Procedure

5Drug Therapy (Chemotherapy)
11/2012 - 01/2008
3Lymph Node Excision (Lymph Node Dissection)
01/2012 - 07/2003
3Hepatectomy
01/2007 - 12/2002
2Therapeutics
12/2010 - 11/2010
2Segmental Mastectomy (Lumpectomy)
01/2010 - 01/2007
2Liver Transplantation
12/2007 - 03/2003
1Radiotherapy
11/2012
1Hysterectomy
11/2012
1Appendectomy
01/2012
1Cesarean Section (Caesarean Section)
01/2012
1Adjuvant Chemotherapy
01/2012
1Gastric Bypass (Roux-en-Y Gastric Bypass)
01/2011
1Palliative Care (Palliative Medicine)
01/2011
1Colectomy
09/2010
1Renal Dialysis (Hemodialysis)
08/2010