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Lars Klareskog Selected Research

Rheumatoid Arthritis

1/2016Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study.
10/2015Interactions between amino acid-defined major histocompatibility complex class II variants and smoking in seropositive rheumatoid arthritis.
9/2015Shared immunological targets in the lungs and joints of patients with rheumatoid arthritis: identification and validation.
5/2015Postmenopausal hormone therapy and the risk of rheumatoid arthritis: results from the Swedish EIRA population-based case-control study.
5/2015Associations with smoking and shared epitope differ between IgA- and IgG-class antibodies to cyclic citrullinated peptides in early rheumatoid arthritis.
5/2015Autoimmunity: lungs and citrullination.
5/2015Gene-gene interaction and RNA splicing profiles of MAP2K4 gene in rheumatoid arthritis.
3/2015Identification of anticitrullinated protein antibody reactivities in a subset of anti-CCP-negative rheumatoid arthritis: association with cigarette smoking and HLA-DRB1 'shared epitope' alleles.
3/2015High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.
2/2015Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins.
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Lars Klareskog Research Topics

Disease

110Rheumatoid Arthritis
01/2016 - 08/2003
24Arthritis (Polyarthritis)
01/2016 - 01/2002
13Inflammation
11/2014 - 01/2004
6Autoimmune Diseases (Autoimmune Disease)
01/2016 - 09/2008
4Systemic Lupus Erythematosus (Libman-Sacks Disease)
06/2013 - 09/2003
3Rheumatic Diseases (Rheumatism)
07/2012 - 02/2004
3Multiple Sclerosis
12/2009 - 05/2005
3Experimental Arthritis
06/2009 - 01/2005
3Lymphoma (Lymphomas)
03/2006 - 06/2003
2Pain (Aches)
01/2015 - 08/2014
2Synovitis
08/2013 - 01/2006
2Joint Diseases (Joint Disease)
05/2012 - 11/2010
2Necrosis
01/2010 - 01/2006
2Myasthenia Gravis
11/2009 - 09/2008
2Infection
10/2007 - 01/2004
2Tetanus
04/2007 - 01/2007
2Celiac Disease (Celiac Sprue)
02/2005 - 06/2002
1Juvenile Rheumatoid Arthritis (Juvenile Idiopathic Arthritis)
01/2016
1Acquired Immunodeficiency Syndrome (AIDS)
01/2016
1Osteoarthritis
01/2016
1Periodontitis
07/2014
1Osteitis
08/2013
1Arthralgia (Joint Pain)
07/2013
1Venous Thrombosis (Deep-Vein Thrombosis)
06/2013
1Vascular Diseases (Vascular Disease)
06/2013
1Bone Resorption
05/2012
1Metabolic Bone Diseases (Osteopenia)
05/2012
1Metrorrhagia (Spotting)
01/2012
1Heart Block
12/2010
1Psoriasis (Pustulosis Palmaris et Plantaris)
11/2010

Drug/Important Bio-Agent (IBA)

36AntibodiesIBA
09/2015 - 06/2002
23Proteins (Proteins, Gene)IBA
05/2015 - 12/2004
17AutoantibodiesIBA
03/2015 - 01/2004
14AntigensIBA
09/2015 - 01/2004
14HLA-DRB1 antigen (HLA DRB1)IBA
05/2015 - 01/2004
13PeptidesIBA
05/2015 - 01/2008
12acetyl 4-aminosalicylic acidIBA
05/2015 - 01/2009
9Methotrexate (Mexate)FDA LinkGeneric
08/2013 - 02/2004
9Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2011 - 09/2003
8Immunoglobulin G (IgG)IBA
01/2016 - 06/2002
8CitrullineIBA
03/2015 - 01/2005
7TNFR-Fc fusion protein (etanercept)FDA Link
11/2009 - 02/2004
6Collagen Type II (Type II Collagen)IBA
07/2013 - 01/2005
6infliximab (Remicade)FDA Link
01/2010 - 01/2005
5Carbon MonoxideIBA
01/2016 - 02/2004
5Rheumatoid FactorIBA
11/2013 - 06/2004
4Immunoglobulin A (IgA)IBA
05/2015 - 06/2002
4Fibrinogen (Factor I)FDA Link
01/2015 - 05/2010
4Biological Markers (Surrogate Marker)IBA
07/2013 - 01/2010
4HLA-DR Antigens (HLA-DR)IBA
03/2013 - 10/2004
4cyclic citrullinated peptideIBA
01/2012 - 01/2004
4AutoantigensIBA
01/2006 - 01/2002
3TNF Receptor-Associated Factor 1IBA
02/2011 - 09/2007
3DNA (Deoxyribonucleic Acid)IBA
01/2010 - 01/2004
3ORALIT (ORS)IBA
11/2009 - 03/2006
2Amino AcidsFDA Link
10/2015 - 03/2012
2Prednisolone (Predate)FDA LinkGeneric
01/2015 - 01/2004
2ametantrone (HAQ)IBA
01/2015 - 08/2014
2Silicon Dioxide (Sand)FDA LinkGeneric
03/2014 - 06/2010
2Reactive Oxygen Species (Oxygen Radicals)IBA
07/2013 - 01/2007
2Phosphopyruvate Hydratase (Enolase)IBA
05/2013 - 12/2009
2VimentinIBA
05/2013 - 01/2008
2Mineral Oil (Liquid Paraffin)FDA LinkGeneric
01/2012 - 01/2005
2prostaglandin-E synthaseIBA
08/2011 - 11/2005
2SmokeIBA
03/2011 - 01/2011
2EpitopesIBA
12/2010 - 01/2005
2CytokinesIBA
07/2010 - 12/2005
2golimumabFDA Link
06/2010 - 01/2010
2Interferon-gamma (Interferon, gamma)IBA
12/2009 - 05/2005
2Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
09/2007 - 09/2003
2Adrenal Cortex Hormones (Corticosteroids)IBA
05/2006 - 02/2004
2triamcinolone hexacetonide (Aristospan)FDA Link
05/2006 - 12/2005
2OilsIBA
01/2005 - 01/2002
2Lipoproteins (Lipoprotein)IBA
01/2005 - 09/2003
2GoldIBA
08/2003 - 01/2002
1HormonesIBA
05/2015
1NicotineFDA Link
10/2014
1abatacept (BELATACEPT)FDA Link
08/2013
1Antirheumatic Agents (DMARD)IBA
07/2013
1Antiphospholipid AntibodiesIBA
06/2013
1HLA-DRB1*04IBA
06/2013
1Tyrosine (L-Tyrosine)FDA Link
01/2013
1HLA-A Antigens (HLA-A)IBA
03/2012
1HLA-DQB1 antigen (HLA DQB1)IBA
03/2012
1HLA-DQA1 (HLA DQA1)IBA
03/2012
1HLA-B Antigens (HLA-B)IBA
03/2012
1HLA-DPB1 (HLA DPB1)IBA
03/2012
1HLA-C Antigens (HLA-C)IBA
03/2012
1HLA-DPA1 (HLA DPA1)IBA
03/2012
1CosmeticsIBA
01/2012
1protein-arginine deiminaseIBA
01/2012
1Anti-Idiotypic AntibodiesIBA
01/2012
1Prostaglandins E (PGE)IBA
08/2011
1Aminocaproic Acids (EAC)FDA LinkGeneric
08/2011
1HLA-DRB1*0405 antigenIBA
01/2011
1Complement System Proteins (Complement)IBA
01/2011
1Mannose-Binding Lectin (Mannan-Binding Lectin)IBA
01/2011
1glutathione S-transferase T1IBA
11/2010

Therapy/Procedure

2Aftercare (After-Treatment)
01/2010 - 10/2006
1Skin Care
01/2012