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Tadamitsu Kishimoto Selected Research

Interleukin-6 (Interleukin 6)

07/2008IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis.
03/2008Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase.
09/2007Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab.
10/2004TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling.
01/2003Synergistic effect on the attenuation of collagen induced arthritis in tumor necrosis factor receptor I (TNFRI) and interleukin 6 double knockout mice.
12/2002Anti-interleukin 6 (IL-6) receptor antibody suppresses Castleman's disease like symptoms emerged in IL-6 transgenic mice.
06/2002Antigen induced arthritis (AIA) can be transferred by bone marrow transplantation: evidence that interleukin 6 is essential for induction of AIA.
02/2002IL-6 transgenic mouse model for extraosseous plasmacytoma.

Articles by Research Topic

Disease

4Rheumatoid Arthritis
05/2008 - 06/2003
3Arthritis (Polyarthritis)
03/2008 - 06/2002
2Colitis
06/2008 - 04/2005
2Juvenile Rheumatoid Arthritis (Juvenile Idiopathic Arthritis)
03/2008 - 01/2005
1Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
07/2008
1Reperfusion Injury
02/2005
1Colonic Neoplasms (Colon Cancer)
10/2004
1Neoplasms (Cancer)
10/2004
1Autoimmune Hemolytic Anemia (Cold Agglutinin Disease)
10/2004
1Amyloidosis
06/2004
1Experimental Arthritis
01/2003
1Giant Lymph Node Hyperplasia (Castleman's Disease)
12/2002
1Plasmacytoma
02/2002

Drug/Important Bio-Agent (IBA)

8Interleukin-6 (Interleukin 6)IBA
07/2008 - 02/2002
4Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
01/2005 - 07/2003
2AntigensIBA
07/2008 - 06/2002
2tocilizumabIBA
05/2008 - 03/2008
1Dextran SulfateIBA
06/2008
1Interleukin-17 (Interleukin 27)IBA
03/2008
1Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)IBA
03/2008
1Cytokine Receptors (Cytokine Receptor)IBA
04/2005
1MetallothioneinIBA
02/2005
1Transforming Growth Factor beta (TGF-beta)IBA
10/2004
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2003
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
01/2003

Therapy/Procedure

1Bone Marrow Transplantation (Transplantation, Bone Marrow)
06/2002