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T Kishimoto Selected Research
Interleukin-6 (Interleukin 6)
09/2006
Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate.
04/2004
Blockade of interleukin-6 receptor suppresses reactive astrogliosis and ameliorates functional recovery in experimental spinal cord injury.
12/2002
Therapeutic benefit of blocking interleukin-6 activity with an anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis: a randomized, double-blind, placebo-controlled, dose-escalation trial.
05/2002
Interleukin-6, tumour necrosis factor alpha and interleukin-1beta in patients with renal cell carcinoma.
01/2002
Discrete roles of cytokines, TNF-alpha, IL-1, IL-6 in tumor promotion and cell transformation.
05/2001
Antitumor effect on murine renal cell carcinoma by autologous tumor vaccines genetically modified with granulocyte-macrophage colony-stimulating factor and interleukin-6 cells.
03/2001
Humanized antibody to human interleukin-6 receptor inhibits the development of collagen arthritis in cynomolgus monkeys.
05/2000
Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo.
05/2000
IL-6 is required for the development of Th1 cell-mediated murine colitis.
01/2000
TNF alpha, IL-1 beta and IL-6 production by peripheral blood monocytes in patients with renal cell carcinoma.
Articles by Research Topic
Disease
4
Lung Neoplasms (Lung Cancer)
04/2001 - 05/2000
3
Rheumatoid Arthritis
09/2006 - 03/2000
3
Renal Cell Carcinoma (Grawitz Tumor)
05/2002 - 01/2000
3
Wilms Tumor (Wilm's Tumor)
05/2000 - 02/2000
2
Necrosis
05/2002 - 03/2000
2
Neoplasms (Cancer)
01/2002 - 02/2000
2
Urinary Bladder Neoplasms (Bladder Cancer)
05/2001 - 06/2000
2
Silicosis
04/2001 - 04/2001
2
Arteriosclerosis
02/2001 - 11/2000
2
Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
10/2000 - 04/2000
2
Colitis
05/2000 - 05/2000
1
Adenocarcinoma
05/2008
1
Chronic Hepatitis C
03/2005
1
Spinal Cord Injuries (Spinal Cord Injury)
04/2004
1
Pulmonary Tuberculosis
10/2001
1
Anoxia (Hypoxia)
08/2001
1
Prostatitis
07/2001
1
Hepatitis
05/2001
1
Acute Kidney Failure (Acute Renal Failure)
05/2001
1
Hypertension (High Blood Pressure)
05/2001
1
Mesothelioma
04/2001
1
Experimental Arthritis
03/2001
1
Hemolytic-Uremic Syndrome
02/2001
1
Cardiac Tamponade
12/2000
1
Rheumatic Diseases (Rheumatism)
11/2000
1
Urinary Calculi (Urinary Calculus)
10/2000
1
Brain Injuries (Brain Injury)
10/2000
1
Shock
10/2000
1
Dissociative Disorders (Fugue)
09/2000
1
Dermatitis
07/2000
1
Graft vs Host Disease (Graft-Versus-Host Disease)
05/2000
1
Crohn Disease (Crohn's Disease)
05/2000
1
Inflammation
05/2000
1
Hyperplasia
03/2000
1
Cardiovascular Diseases (Cardiovascular Disease)
02/2000
1
Cardiomyopathies (Cardiomyopathy)
01/2000
1
Neoplasm Metastasis (Metastasis)
01/2000
1
Carcinoma (Carcinomatosis)
01/2000
Drug/Important Bio-Agent (IBA)
10
Interleukin-6 (Interleukin 6)
IBA
09/2006 - 01/2000
3
Cytokines
IBA
01/2002 - 02/2000
3
Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
IBA
01/2002 - 01/2000
3
Asbestos
IBA
04/2001 - 05/2000
2
Interleukin-1beta (Interleukin 1 beta)
IBA
05/2002 - 01/2000
2
STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)
IBA
08/2001 - 01/2000
1
Adenosine Triphosphate (ATP)
IBA
05/2008
1
tocilizumab
IBA
09/2006
1
Methotrexate (Mexate)
FDA Link
Generic
09/2006
1
Interferons
IBA
03/2005
1
Interleukin-1 (Interleukin 1)
IBA
01/2002
1
Immunoglobulin G (IgG)
IBA
10/2001
1
Superoxide Dismutase
IBA
08/2001
1
cernilton
IBA
07/2001
1
Hormones
IBA
07/2001
1
Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
IBA
05/2001
1
Interleukin-4 (Interleukin 4)
IBA
05/2001
1
Angiotensinogen
IBA
05/2001
1
Cancer Vaccines
IBA
05/2001
1
Hepatocyte Growth Factor (Growth Factor, Hepatocyte)
IBA
05/2001
1
pirarubicin
IBA
05/2001
1
Type I DNA Topoisomerases (Topoisomerase I)
IBA
04/2001
1
Autoantibodies
IBA
04/2001
1
HLA-DQB1 (HLA DQB1)
IBA
04/2001
1
Type 1 Angiotensin Receptor
IBA
02/2001
1
globotriaosylceramide (globotriosylceramide)
IBA
02/2001
1
Interleukin-6 Receptors (Interleukin 6 Receptor)
IBA
11/2000
1
Myosin Heavy Chains (Myosin Heavy Chain)
IBA
11/2000
1
Carbamazepine (Tegretol)
FDA Link
Generic
10/2000
1
Proteasome Endopeptidase Complex (Proteasome)
IBA
09/2000
1
Cyclin B
IBA
09/2000
1
Immunoglobulin E (IgE)
IBA
07/2000
1
astragalin
IBA
07/2000
1
wogonin
IBA
06/2000
1
baicalin
IBA
06/2000
1
baicalein
IBA
06/2000
1
Tacrolimus (Prograf)
FDA Link
05/2000
1
DNA (Deoxyribonucleic Acid)
IBA
05/2000
1
tamsulosin (Flomax)
FDA Link
04/2000
1
terazosine (terazosin)
FDA Link
Generic
04/2000
1
Peptides
IBA
02/2000
1
Doxorubicin (Adriamycin)
FDA Link
Generic
01/2000
1
Antigens
IBA
01/2000
Therapy/Procedure
2
Transplants (Transplant)
02/2001 - 11/2000
1
Homologous Transplantation (Allograft)
02/2001
1
Pericardiectomy
12/2000
1
Lithotripsy (Extracorporeal Shockwave Lithotripsy)
10/2000
1
Lasers (Laser)
10/2000
1
Prostatectomy (Retropubic Prostatectomy)
10/2000
1
Transplantation (Transplant Recipients)
05/2000
1
Immunotherapy
02/2000