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Seung U Kim Selected Research

Flucytosine (Ancobon)

1/2014Selective antitumor effect of neural stem cells expressing cytosine deaminase and interferon-beta against ductal breast cancer cells in cellular and xenograft models.
5/2013Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies.
6/2012Antitumor effects of genetically engineered stem cells expressing yeast cytosine deaminase in lung cancer brain metastases via their tumor-tropic properties.
10/2011Genetically engineered stem cells expressing cytosine deaminase and interferon-β migrate to human lung cancer cells and have potentially therapeutic anti-tumor effects.
4/2010Influence of the prodrugs 5-fluorocytosine and CPT-11 on ovarian cancer cells using genetically engineered stem cells: tumor-tropic potential and inhibition of ovarian cancer cell growth.
8/2009Targeting rat brainstem glioma using human neural stem cells and human mesenchymal stem cells.
3/2009Human neural stem cells can target and deliver therapeutic genes to breast cancer brain metastases.
1/2009Iron labeling and pre-clinical MRI visualization of therapeutic human neural stem cells in a murine glioma model.

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Seung U Kim Research Topics

Disease

45Neoplasms (Cancer)
07/2015 - 06/2005
20Glioma (Gliomas)
10/2013 - 01/2004
19Stroke (Strokes)
01/2015 - 09/2004
14Brain Ischemia (Cerebral Ischemia)
11/2013 - 09/2003
13Spinal Cord Injuries (Spinal Cord Injury)
01/2015 - 01/2007
13Ischemia
02/2012 - 06/2003
12Neuroblastoma
01/2009 - 08/2002
11Brain Neoplasms (Brain Tumor)
10/2013 - 06/2005
10Alzheimer Disease (Alzheimer's Disease)
03/2014 - 09/2003
10Parkinson Disease (Parkinson's Disease)
06/2013 - 07/2003
7Neoplasm Metastasis (Metastasis)
01/2015 - 01/2008
7Nervous System Diseases (Neurological Disorders)
10/2012 - 08/2005
7Huntington Disease (Huntington's Disease)
04/2008 - 10/2003
5Inflammation
01/2015 - 03/2008
5Breast Neoplasms (Breast Cancer)
12/2014 - 01/2009
5Neurodegenerative Diseases (Neurodegenerative Disease)
10/2013 - 05/2009
5Anoxia (Hypoxia)
01/2013 - 04/2004
4Glioblastoma (Glioblastoma Multiforme)
01/2015 - 07/2005
4Brain Injuries (Brain Injury)
03/2013 - 09/2002
4Cerebral Hemorrhage
11/2010 - 09/2003
3Fibrosis (Cirrhosis)
01/2015 - 01/2012
3Lung Neoplasms (Lung Cancer)
12/2014 - 10/2011
3Necrosis
12/2014 - 01/2008
3Urinary Bladder Neck Obstruction (Bladder Neck Obstruction)
01/2013 - 01/2012
3Memory Disorders (Memory Loss)
04/2012 - 01/2012
2Endometrial Neoplasms (Endometrial Cancer)
07/2015 - 09/2011
2Melanoma (Melanoma, Malignant)
01/2015 - 09/2010
2Disease Progression
01/2014 - 01/2009
2Prostatic Neoplasms (Prostate Cancer)
07/2013 - 06/2008
2Atrophy
05/2013 - 07/2005
2Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/2013 - 04/2010
2Gliosis
01/2013 - 01/2010
2Carcinoma (Carcinomatosis)
04/2012 - 10/2011
2Multiple Sclerosis
10/2011 - 08/2005
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2011 - 05/2011
2Medulloblastoma
04/2011 - 09/2006
2Seizures (Seizure)
01/2010 - 08/2006

Drug/Important Bio-Agent (IBA)

17Cytosine DeaminaseIBA
01/2014 - 01/2009
13Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2015 - 04/2004
9Carbon MonoxideIBA
07/2015 - 10/2005
8Fluorouracil (Carac)FDA LinkGeneric
07/2015 - 03/2009
8Flucytosine (Ancobon)FDA Link
01/2014 - 01/2009
8Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2011 - 01/2004
7InterferonsIBA
07/2015 - 09/2011
7CytokinesIBA
01/2015 - 10/2002
7irinotecan (Camptosar)FDA LinkGeneric
12/2014 - 01/2006
5EnzymesIBA
01/2014 - 04/2010
5Interferon-betaIBA
01/2014 - 01/2007
5ProdrugsIBA
04/2012 - 04/2010
5Conditioned Culture MediaIBA
02/2012 - 04/2008
5Caspase 3 (Caspase-3)IBA
01/2011 - 01/2004
4CM-DiIIBA
07/2015 - 01/2007
4Amyloid (Amyloid Fibrils)IBA
01/2015 - 09/2003
4CollagenIBA
01/2015 - 01/2012
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2014 - 06/2005
4Interleukin-6 (Interleukin 6)IBA
02/2012 - 01/2008
4Transcription Factors (Transcription Factor)IBA
07/2011 - 05/2007
4Interleukin-8 (Interleukin 8)IBA
09/2010 - 02/2005
3Messenger RNA (mRNA)IBA
01/2015 - 07/2005
3LuciferasesIBA
01/2014 - 11/2008
3Nerve Growth Factors (Neurotrophins)IBA
05/2013 - 01/2010
3Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
10/2012 - 09/2004
3Carboxylesterase (Hydrolase S)IBA
02/2012 - 01/2007
3Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
01/2012 - 06/2008
3OxygenIBA
06/2011 - 08/2005
3CaspasesIBA
03/2010 - 01/2004
3Complementary DNA (cDNA)IBA
01/2007 - 09/2004
3Quinolinic AcidIBA
07/2005 - 10/2003
2RNA (Ribonucleic Acid)IBA
01/2015 - 01/2013
2GoldIBA
12/2014 - 07/2013
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
01/2014 - 09/2011
2Stem Cell FactorIBA
01/2014 - 09/2011
2HormonesIBA
07/2013 - 09/2012
2Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2013 - 11/2010
2Choline O-Acetyltransferase (Choline Acetyltransferase)IBA
04/2012 - 01/2012
2Glial Fibrillary Acidic ProteinIBA
02/2012 - 01/2010
2Kainic Acid (Kainate)IBA
01/2012 - 01/2010
2Chemokine CX3CL1IBA
03/2011 - 08/2002
2Dopamine (Intropin)FDA LinkGeneric
12/2010 - 07/2007
2Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA
01/2010 - 06/2004
2AntibodiesIBA
01/2009 - 12/2008
2IronIBA
01/2009 - 05/2008
2Urokinase Plasminogen Activator ReceptorsIBA
12/2008 - 06/2008
2Small Interfering RNA (siRNA)IBA
12/2008 - 01/2008
2Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
12/2008 - 06/2008
2Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
07/2008 - 05/2007
2Cytokine Receptors (Cytokine Receptor)IBA
01/2008 - 10/2002
2Cystatin CIBA
01/2008 - 12/2005
2Cyclooxygenase 2 (Cyclooxygenase-2)IBA
08/2006 - 07/2006

Therapy/Procedure

45Transplantation (Transplant Recipients)
01/2015 - 06/2003
11Heterologous Transplantation (Xenotransplantation)
07/2015 - 12/2008
10Tissue Therapy (Cell Therapy)
01/2015 - 01/2007
8Drug Therapy (Chemotherapy)
07/2013 - 07/2007
4Therapeutics
10/2014 - 01/2009
3Transplants (Transplant)
09/2014 - 05/2007
3Intravenous Injections
10/2013 - 01/2012
3Radiotherapy
09/2012 - 07/2007
3Cell Transplantation
07/2008 - 09/2003
2Mesenchymal Stem Cell Transplantation
01/2015 - 03/2011
2Injections
12/2014 - 01/2007