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Takehiro Kawashiri Selected Research

Peripheral Nervous System Diseases (PNS Diseases)

9/2015Behavioral and pharmacological characteristics of bortezomib-induced peripheral neuropathy in rats.
1/2015Exenatide Facilitates Recovery from Oxaliplatin-Induced Peripheral Neuropathy in Rats.
3/2014Neurotropin® relieves oxaliplatin-induced neuropathy via Gi protein-coupled receptors in the monoaminergic descending pain inhibitory system.
3/2014Oxaliplatin induces hypomyelination and reduced neuregulin 1 expression in the rat sciatic nerve.
2/2013Calcium channel blockers reduce oxaliplatin-induced acute neuropathy: a retrospective study of 69 male patients receiving modified FOLFOX6 therapy.
2/2013[Evidence from basic studies on mechanisms and treatment drugs for oxaliplatin-induced peripheral neuropathy].
6/2012Goshajinkigan reduces oxaliplatin-induced peripheral neuropathy without affecting anti-tumour efficacy in rodents.
1/2012Inhibition of Ca2+/calmodulin-dependent protein kinase II reverses oxaliplatin-induced mechanical allodynia in rats.
4/2011Involvement of substance P in peripheral neuropathy induced by paclitaxel but not oxaliplatin.
4/2011Prevention of oxaliplatin-induced mechanical allodynia and neurodegeneration by neurotropin in the rat model.
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Takehiro Kawashiri Research Topics

Disease

16Hyperalgesia
11/2015 - 01/2009
15Peripheral Nervous System Diseases (PNS Diseases)
09/2015 - 01/2009
9Colorectal Neoplasms (Colorectal Cancer)
01/2015 - 12/2009
5Pain (Aches)
03/2014 - 01/2010
3Neoplasms (Cancer)
01/2015 - 01/2011
2Paresthesia (Dysesthesia)
09/2015 - 12/2009
2Hypesthesia (Numbness)
09/2015 - 06/2012
2Hypersensitivity (Allergy)
07/2011 - 04/2011
1Multiple Myeloma
09/2015
1Type 2 Diabetes Mellitus (MODY)
01/2015
1Adenocarcinoma
01/2015
1Body Weight (Weight, Body)
11/2014
1Nausea
07/2011
1Vomiting
07/2011
1Pheochromocytoma
04/2011
1Neuralgia (Stump Neuralgia)
01/2010
1Diabetic Neuropathies (Diabetic Neuropathy)
01/2010
1Necrosis
10/2007

Drug/Important Bio-Agent (IBA)

14oxaliplatin (Eloxatin)FDA LinkGeneric
01/2015 - 12/2009
5AcetoneIBA
03/2014 - 12/2009
4Paclitaxel (Taxol)FDA LinkGeneric
07/2011 - 01/2009
3Mexiletine (Mexitil)FDA LinkGeneric
09/2015 - 01/2010
2bortezomib (Velcade)FDA Link
11/2015 - 09/2015
2gosha-jinki-ganIBA
11/2015 - 06/2012
2Amitriptyline (Elavil)FDA LinkGeneric
09/2015 - 01/2012
2Carbon MonoxideIBA
01/2015 - 01/2012
2neurotropinIBA
03/2014 - 04/2011
2N-Methylaspartate (NMDA)IBA
01/2012 - 01/2011
2N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
01/2012 - 01/2011
2Messenger RNA (mRNA)IBA
01/2012 - 01/2012
2Substance PIBA
07/2011 - 04/2011
2pemirolast (Alamast)FDA Link
07/2011 - 04/2011
2Cisplatin (Platino)FDA LinkGeneric
07/2011 - 10/2007
2PlatinumIBA
01/2011 - 01/2010
1kappa Opioid Receptors (kappa Opioid Receptor)IBA
11/2015
1duloxetine (Cymbalta)FDA Link
09/2015
1Diclofenac (SR 38)FDA LinkGeneric
09/2015
1pregabalin (Lyrica)FDA Link
09/2015
1TramadolFDA LinkGeneric
09/2015
1Analgesics (Analgesic Drugs)IBA
09/2015
1IncretinsIBA
01/2015
1Glucagon-Like Peptide 1 (GLP 1)IBA
01/2015
1exenatide (Byetta)FDA Link
01/2015
1CreatinineIBA
11/2014
1Calcium Channel Blockers (Blockers, Calcium Channel)IBA
02/2013
1KN 93IBA
01/2012
1Trifluoperazine (Stelazine)FDA LinkGeneric
01/2012
1Calcium-Calmodulin-Dependent Protein KinasesIBA
01/2012
1Diltiazem (Cardizem)FDA LinkGeneric
01/2012
1Protein Kinases (Protein Kinase)IBA
01/2012
1Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
01/2012
1Calmodulin (Calcium-Dependent Activator Protein)IBA
01/2012
1Nifedipine (Adalat)FDA LinkGeneric
01/2012
1Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA
07/2011
1TachykininsIBA
07/2011
1Serotonin (5 Hydroxytryptamine)IBA
07/2011
1KaolinIBA
07/2011
1Memantine (Namenda)FDA Link
01/2011
1albumin-bound paclitaxelFDA Link
01/2011
17-nitroindazoleIBA
01/2011
1NG-Nitroarginine Methyl Ester (L-NAME)IBA
01/2011
1ifenprodilIBA
01/2011
1Dizocilpine Maleate (Dizocilpine)IBA
01/2011
1130-nm albumin-bound paclitaxelIBA
01/2011
1Lidocaine (Xylocaine)FDA LinkGeneric
01/2010
11,2-cyclohexanediamine (dach)IBA
12/2009
1MagnesiumIBA
12/2009
1CalciumIBA
12/2009
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2007
1SB 203580IBA
10/2007
1pifithrinIBA
10/2007
1p38 Mitogen-Activated Protein KinasesIBA
10/2007
1Acetylcysteine (Siran)FDA LinkGeneric
10/2007

Therapy/Procedure

5Drug Therapy (Chemotherapy)
02/2013 - 01/2010
2Kampo Medicine (Kampo)
11/2015 - 06/2012
2Oral Administration
09/2015 - 01/2012
1Spinal Injections
01/2011