Methotrexate FDA Link Generic

An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.

Also Known As:

Mexate; Methotrexate Hydrate; Methotrexate, (D)-Isomer; Methotrexate, (DL)-Isomer; Methotrexate, Dicesium Salt; Methotrexate, Disodium Salt; Methotrexate, Sodium Salt; Dicesium Salt Methotrexate; Disodium Salt Methotrexate; Hydrate, Methotrexate; Sodium Salt Methotrexate; Amethopterin; L-Glutamic acid, N- (4- (((2,4- diamino- 6- pteridinyl)methyl)methylamino)benzoyl)-

Pharmalogical Action Categories:

Abortifacient Agents, Nonsteroidal
Antimetabolites, Antineoplastic
Antirheumatic Agents
Dermatologic Agents
Enzyme Inhibitors
Folic Acid Antagonists
Immunosuppressive Agents
Nucleic Acid Synthesis Inhibitors

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Heterocyclic Compounds: 25

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2-Ring Heterocyclic Compounds

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Pteridines: 30

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Pterins: 41

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Aminopterin: 225

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Methotrexate: 12403

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Drug/Important Bio-Agent (IBA)