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Robert P Jankov Selected Research

Y 27632

6/2015Rho kinase mediates right ventricular systolic dysfunction in rats with chronic neonatal pulmonary hypertension.
1/2014Rho-kinase inhibitor prevents bleomycin-induced injury in neonatal rats independent of effects on lung inflammation.
12/2010Rescue treatment with a Rho-kinase inhibitor normalizes right ventricular function and reverses remodeling in juvenile rats with chronic pulmonary hypertension.
6/2008Vascular remodeling protects against ventilator-induced lung injury in the in vivo rat.
2/2008Acute vasodilator effects of Rho-kinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide.

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Robert P Jankov Research Topics

Disease

18Pulmonary Hypertension (Ayerza Syndrome)
06/2015 - 07/2002
14Anoxia (Hypoxia)
06/2015 - 11/2006
13Lung Injury
07/2015 - 07/2002
9Hypercapnia
04/2014 - 12/2003
8Bronchopulmonary Dysplasia
03/2015 - 01/2004
5Right Ventricular Hypertrophy
01/2014 - 06/2008
3Inflammation
03/2015 - 07/2012
2Body Weight (Weight, Body)
10/2014 - 05/2013
2Hyperoxia
11/2012 - 11/2009
2Acidosis
11/2008 - 11/2006
1Necrosis
01/2015
1Necrotizing Enterocolitis
01/2015
1Hemolysis
08/2014
1Pneumonia (Pneumonitis)
01/2014
1Right Ventricular Dysfunction
11/2010
1Cardiomegaly (Heart Hypertrophy)
11/2010
1Edema
06/2008
1Hyperplasia
06/2005
1Ischemia
03/2005
1Hypocapnia
03/2005
1Reperfusion Injury
12/2003
1Hypertrophy
07/2002
1Pulmonary Fibrosis (Hamman Rich Syndrome)
05/2002
1Fibrosis (Cirrhosis)
05/2002

Drug/Important Bio-Agent (IBA)

9Peroxynitrous Acid (Peroxynitrite)IBA
07/2015 - 11/2009
8rho-Associated KinasesIBA
06/2015 - 02/2008
8Nitric Oxide (Nitrogen Monoxide)FDA Link
04/2014 - 09/2005
5Y 27632IBA
06/2015 - 02/2008
5Bleomycin (Blenoxane)FDA LinkGeneric
03/2015 - 05/2002
5Carbon MonoxideIBA
07/2012 - 11/2006
5OxygenIBA
03/2011 - 07/2002
3Superoxides (Superoxide)IBA
08/2013 - 02/2008
33-nitrotyrosineIBA
11/2010 - 02/2008
3Endothelins (Endothelin)IBA
11/2006 - 06/2005
38-epi-prostaglandin F2alphaIBA
11/2006 - 03/2005
3Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
10/2005 - 01/2004
2fasudil (AT 877)IBA
06/2015 - 02/2008
2Type 5 Cyclic Nucleotide PhosphodiesterasesIBA
06/2015 - 11/2010
2ArginaseIBA
03/2015 - 10/2009
2CollagenIBA
03/2015 - 05/2002
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2014 - 07/2012
2Nitric Oxide Synthase (NO Synthase)IBA
04/2014 - 06/2010
2glucuronyl glucosamine glycan sulfate (Vessel)IBA
11/2009 - 07/2002
2Endothelin-1 (Endothelin 1)IBA
11/2006 - 07/2002
2Carbon DioxideIBA
11/2006 - 12/2003
1Leukocyte Elastase (Neutrophil Elastase)IBA
07/2015
1ElastinIBA
07/2015
1Secretory Proteinase Inhibitory ProteinsIBA
07/2015
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
03/2015
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2015
1Dexamethasone (Maxidex)FDA LinkGeneric
10/2014
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
10/2014
1Anti-Inflammatory Agents (Anti-Inflammatories)IBA
10/2014
1PotassiumIBA
08/2014
1InterleukinsIBA
04/2014
11- (2- bromophenyl)- 3- (7- cyano- 3H- benzotriazol- 4- yl)ureaIBA
01/2014
1Vasodilator Agents (Vasodilators)IBA
01/2014
1sildenafil (Viagra)FDA Link
01/2014
1IGF Type 1 Receptor (IGF 1 Receptor)IBA
05/2013
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
11/2012
15'-Guanylic Acid (GMP)IBA
06/2012
1Small Interfering RNA (siRNA)IBA
12/2010
1NitratesIBA
06/2010
1Nitroarginine (NG Nitro L Arginine)IBA
06/2010
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2009
1Tyrosine (L-Tyrosine)FDA Link
11/2009
1Angiopoietin-1IBA
11/2009
115-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic AcidIBA
10/2009
1Interleukin-1 (Interleukin 1)IBA
09/2009
1Interleukin-1beta (Interleukin 1 beta)IBA
09/2009
1Idiopathic pulmonary hypertensionIBA
06/2008
1tempolIBA
02/2008
1Allopurinol (Remid)FDA LinkGeneric
02/2008
1Reactive Oxygen Species (Oxygen Radicals)IBA
02/2008
1Xanthine OxidaseIBA
02/2008
1Prostaglandin H2 Thromboxane A2 ReceptorsIBA
09/2006
1AntioxidantsIBA
09/2006
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
10/2005
1DNA (Deoxyribonucleic Acid)IBA
06/2005
1platelet-derived growth factor BB (becaplermin)FDA Link
06/2005
1IsoprostanesIBA
03/2005
1Alanine Transaminase (SGPT)IBA
03/2005
1salicylhydroxamic acid (SHAM)IBA
03/2005
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
07/2002

Therapy/Procedure

1Resuscitation
11/2012
1Parenteral Nutrition
03/2011
1Subcutaneous Injections
12/2010
1Neonatal Intensive Care
11/2008
1Artificial Respiration (Mechanical Ventilation)
06/2008
1Lasers (Laser)
03/2005
1High-Frequency Ventilation
03/2005