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Hartmut Jaeschke Selected Research

Necrosis

01/2008Mitochondrial bax translocation accelerates DNA fragmentation and cell necrosis in a murine model of acetaminophen hepatotoxicity.
03/2005Pathophysiological role of poly(ADP-ribose) polymerase (PARP) activation during acetaminophen-induced liver cell necrosis in mice.
11/2004Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes.
10/2004Reduced oncotic necrosis in Fas receptor-deficient C57BL/6J-lpr mice after bile duct ligation.
07/2003Oncotic necrosis and caspase-dependent apoptosis during galactosamine-induced liver injury in rats.
06/2002Mode of cell death after acetaminophen overdose in mice: apoptosis or oncotic necrosis?

Articles by Research Topic

Disease

6Necrosis
01/2008 - 06/2002
2Inflammation
09/2007 - 10/2005
2Reperfusion Injury
10/2005 - 05/2003
2Endotoxemia
05/2005 - 07/2004
1Sclerosing Cholangitis
02/2006
1Cholestasis
02/2006
1Cholangitis
02/2006
1DNA Damage
11/2005
1Hepatocellular Carcinoma (Hepatoma)
09/2005
1Hemorrhage
06/2003
1Ischemia
09/2002

Drug/Important Bio-Agent (IBA)

7Acetaminophen (Paracetamol)FDA LinkGeneric
01/2008 - 06/2002
2CD95 Antigens (fas Receptor)IBA
09/2007 - 10/2004
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
09/2007
1Lithocholic AcidIBA
02/2006
1Ursodeoxycholic Acid (Urso)FDA LinkGeneric
02/2006
124-norursodeoxycholic acidIBA
02/2006
1Peroxynitrous Acid (Peroxynitrite)IBA
11/2005
1Hypochlorous Acid (Hypochlorite)IBA
10/2005
1Proteins (Proteins, Gene)IBA
10/2005
1Glycogen Synthase (Synthase I)IBA
09/2005
1CXC ChemokinesIBA
05/2005
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
03/2005
1NADPH Oxidase (NAD(P)H oxidase)IBA
07/2004
1GalactosamineIBA
07/2003
1Adenosine Triphosphate (ATP)IBA
06/2003
1Reactive Oxygen Species (Oxygen Radicals)IBA
05/2003
1Xanthine OxidaseIBA
09/2002

Therapy/Procedure

2Ligation
09/2007 - 10/2004
1Resuscitation
06/2003