Antineutrophil Cytoplasmic Antibodies

Autoantibodies directed against cytoplasmic constituents of POLYMORPHONUCLEAR LEUKOCYTES and/or MONOCYTES. They are used as specific markers for WEGENER GRANULOMATOSIS and other diseases, though their pathophysiological role is not clear. ANCA are routinely detected by indirect immunofluorescence with three different patterns: c-ANCA (cytoplasmic), p-ANCA (perinuclear), and atypical ANCA.

Also Known As:

ANCA; Anti-Neutrophil Cytoplasmic Antibody; Antineutrophil Cytoplasmic Antibody; Antibodies, Antineutrophil Cytoplasmic; Anti-Neutrophil Cytoplasmic Antibodies; Anti Neutrophil Cytoplasmic Antibodies; Anti Neutrophil Cytoplasmic Antibody; Antibodies, Anti-Neutrophil Cytoplasmic; Antibody, Anti-Neutrophil Cytoplasmic; Antibody, Antineutrophil Cytoplasmic; Cytoplasmic Antibodies, Anti-Neutrophil; Cytoplasmic Antibodies, Antineutrophil; Cytoplasmic Antibody, Anti-Neutrophil; Cytoplasmic Antibody, Antineutrophil; c ANCA; p ANCA; c-ANCA; p-ANCA

Pharmalogical Action Categories:

Immunologic Factors

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Amino Acids, Peptides, and Proteins

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Proteins: 58433

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Blood Proteins: 3862

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Serum Globulins: 74

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Immunoglobulins: 20136

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Antibodies: 77322

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Autoantibodies: 14185

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Antineutrophil Cytoplasmic Antibodies: 3087

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Immunoproteins: 30

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Immunoglobulins: 20136

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Antibodies: 77322

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Autoantibodies: 14185

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Antineutrophil Cytoplasmic Antibodies: 3087

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Globulins: 305

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Serum Globulins: 74

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Immunoglobulins: 20136

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Antibodies: 77322

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Autoantibodies: 14185

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Antineutrophil Cytoplasmic Antibodies: 3087

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Biological Factors: 931

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Biological Markers: 21607

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Antineutrophil Cytoplasmic Antibodies: 3087

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Disease

Drug/Important Bio-Agent (IBA)