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Robert E Humphreys Selected Research

invariant chain (Ii-Key)

5/2007Ii-Key/HER-2/neu(776-790) hybrid peptides induce more effective immunological responses over the native peptide in lymphocyte cultures from patients with HER-2/neu+ tumors.
12/2006Ii-Key/MHC class II epitope hybrids: a strategy that enhances MHC class II epitope loading to create more potent peptide vaccines.
1/2006Ii-Key/MHC class II epitope peptides as helper T cell vaccines for cancer and infectious disease.
7/2005Enhanced CD4+ T-cell response in DR4-transgenic mice to a hybrid peptide linking the Ii-Key segment of the invariant chain to the melanoma gp100(48-58) MHC class II epitope.
6/2004Ii-Key/HER-2/neu MHC class-II antigenic epitope vaccine peptide for breast cancer.

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Robert E Humphreys Research Topics

Disease

7Neoplasms (Cancer)
05/2007 - 10/2003
2Communicable Diseases (Infectious Diseases)
12/2006 - 01/2006
1Melanoma (Melanoma, Malignant)
07/2005
1Breast Neoplasms (Breast Cancer)
06/2004
1Carcinoma (Carcinomatosis)
06/2004

Drug/Important Bio-Agent (IBA)

6PeptidesIBA
05/2007 - 05/2004
5invariant chain (Ii-Key)IBA
05/2007 - 06/2004
3AntigensIBA
06/2004 - 04/2004
2VaccinesIBA
01/2006 - 06/2004
2Subunit VaccinesIBA
01/2006 - 06/2004
2EpitopesIBA
05/2004 - 04/2004
1Neoplasm Antigens (Tumor Antigens)IBA
06/2004
1Proteins (Proteins, Gene)IBA
06/2004
1HLA-DR Antigens (HLA-DR)IBA
05/2004
1MHC class II transactivator proteinIBA
10/2003
1Interleukin-2 (IL2)IBA
10/2003

Therapy/Procedure

4Immunotherapy
01/2006 - 10/2003
1Injections
10/2003