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Tom W J Huizinga Selected Research

Rheumatoid Arthritis

10/2015Anti-carbamylated protein antibodies in rheumatoid arthritis patients of Asian descent.
8/2015Genetic Factors for the Severity of ACPA-negative Rheumatoid Arthritis in 2 Cohorts of Early Disease: A Genome-wide Study.
6/2015Sarilumab Plus Methotrexate in Patients With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate: Results of a Phase III Study.
5/2015Comparative Efficacy of Novel DMARDs as Monotherapy and in Combination with Methotrexate in Rheumatoid Arthritis Patients with Inadequate Response to Conventional DMARDs: A Network Meta-Analysis.
4/2015Anti-carbamylated protein antibodies are present prior to rheumatoid arthritis and are associated with its future diagnosis.
1/2015Anti-citrullinated protein antibodies contribute to platelet activation in rheumatoid arthritis.
1/2015Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis.
1/2015Evaluating drug-free remission with abatacept in early rheumatoid arthritis: results from the phase 3b, multicentre, randomised, active-controlled AVERT study of 24 months, with a 12-month, double-blind treatment period.
1/2015Retraction Note: Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium.
1/2015The specificity of anti-carbamylated protein antibodies for rheumatoid arthritis in a setting of early arthritis.
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Tom W J Huizinga Research Topics

Disease

108Rheumatoid Arthritis
10/2015 - 03/2003
38Arthritis (Polyarthritis)
08/2015 - 02/2004
16Inflammation
06/2015 - 06/2004
12Osteoarthritis
01/2015 - 08/2003
7Autoimmune Diseases (Autoimmune Disease)
09/2015 - 12/2004
6Arthralgia (Joint Pain)
01/2015 - 04/2013
6Experimental Arthritis
01/2015 - 10/2004
5Pain (Aches)
07/2013 - 10/2008
4Synovitis
05/2015 - 07/2010
4Necrosis
12/2013 - 02/2007
4Fibrosis (Cirrhosis)
06/2005 - 10/2003
3Infection
01/2013 - 11/2005
3Wounds and Injuries (Trauma)
01/2013 - 03/2003
3Systemic Lupus Erythematosus (Libman-Sacks Disease)
12/2006 - 04/2002
2Chronic Disease (Chronic Diseases)
03/2014 - 09/2004
2Cardiovascular Diseases (Cardiovascular Disease)
03/2014 - 06/2004
2Rubella (German Measles)
01/2012 - 01/2007
2Leprosy (Hansen's Disease)
06/2004 - 12/2002
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
05/2002 - 04/2002
2Multiple Sclerosis
05/2002 - 04/2002
1Tenosynovitis
05/2015
1Reactive Arthritis (Reiter Disease)
01/2015
1Muscle Weakness
01/2015
1Psoriatic Arthritis
01/2015
1Body Weight (Weight, Body)
01/2015
1Fatigue
01/2015
1Edema
01/2015
1Lupus Nephritis
11/2014
1Neutropenia
09/2014
1Anterior Uveitis
03/2014
1Bone Resorption
01/2014
1Obesity
08/2013
1Transverse Myelitis (Necrotizing Myelitis)
06/2013

Drug/Important Bio-Agent (IBA)

42AntibodiesIBA
10/2015 - 02/2004
18Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2014 - 01/2002
17Methotrexate (Mexate)FDA LinkGeneric
06/2015 - 04/2006
14AntigensIBA
09/2015 - 10/2004
14AutoantibodiesIBA
05/2015 - 02/2004
11Antirheumatic Agents (DMARD)IBA
05/2015 - 10/2006
9cyclic citrullinated peptideIBA
04/2013 - 01/2005
9Interleukin-10 (Interleukin 10)IBA
08/2005 - 04/2002
8Aminocaproic Acids (EAC)FDA LinkGeneric
01/2015 - 08/2005
8Proteins (Proteins, Gene)IBA
01/2014 - 01/2005
7Immunoglobulin G (IgG)IBA
01/2015 - 01/2006
6Rheumatoid FactorIBA
05/2015 - 01/2007
6acetyl 4-aminosalicylic acidIBA
01/2012 - 01/2007
5CollagenIBA
01/2015 - 07/2004
5rituximab (Mabthera)FDA Link
11/2014 - 12/2007
54-hexyloxyaniline (HOA)IBA
05/2014 - 07/2010
4PeptidesIBA
01/2015 - 07/2004
4Immunoglobulin M (IgM)IBA
04/2014 - 01/2006
4Prednisone (Sone)FDA LinkGeneric
06/2013 - 05/2009
4VimentinIBA
07/2011 - 08/2009
4HLA-DRB1 antigen (HLA DRB1)IBA
05/2010 - 10/2005
3abatacept (BELATACEPT)FDA Link
01/2015 - 09/2010
3C-Reactive ProteinIBA
01/2015 - 09/2013
3InterleukinsIBA
01/2015 - 12/2002
3Fibrinogen (Factor I)FDA Link
10/2014 - 01/2011
3AdiponectinIBA
05/2014 - 07/2011
3EpitopesIBA
02/2012 - 08/2010
3TNF Receptor-Associated Factor 1IBA
02/2011 - 09/2007
3Messenger RNA (mRNA)IBA
06/2010 - 10/2003
3Interleukin-1 (Interleukin 1)IBA
05/2005 - 05/2002
3Interleukin-1beta (Interleukin 1 beta)IBA
05/2005 - 05/2002
2GadoliniumIBA
05/2015 - 10/2014
2CitrullineIBA
01/2015 - 02/2012
2Collagen Type II (Type II Collagen)IBA
01/2015 - 01/2014
2Carbon MonoxideIBA
01/2015 - 10/2005
2LipidsIBA
09/2014 - 08/2013
2pyridinolineIBA
08/2013 - 07/2004
2TNFR-Fc fusion protein (etanercept)FDA Link
03/2013 - 02/2007
2amsonic acid (DAS)IBA
06/2012 - 06/2009
2ResistinIBA
09/2011 - 07/2011
2LeptinIBA
09/2011 - 07/2011
2Interleukin-6 (Interleukin 6)IBA
09/2011 - 09/2004
2AdipokinesIBA
09/2011 - 07/2011
2Phosphopyruvate Hydratase (Enolase)IBA
07/2011 - 01/2011
2CytokinesIBA
01/2011 - 09/2004
2Insulin (Novolin)FDA Link
06/2010 - 02/2005
2Prednisolone (Predate)FDA LinkGeneric
06/2010 - 02/2007
2HLA-DR Antigens (HLA-DR)IBA
12/2007 - 07/2004
2adalimumab (Humira)FDA Link
02/2007 - 02/2006
22-Oxoglutarate 5-Dioxygenase Procollagen-Lysine (Lysyl Hydroxylase)IBA
06/2005 - 10/2003
2Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
09/2004 - 05/2002
1Galactose (Galactopyranose)FDA LinkGeneric
01/2015
1OxygenIBA
01/2015
1belimumabIBA
11/2014
13-benzoyl dopamine (MBDA)IBA
11/2014
1TransaminasesIBA
09/2014
1Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
09/2014
1HLA-B60IBA
03/2014
1Freund's AdjuvantIBA
01/2014
1TNF Receptor-Associated Factor 6 (TRAF6)IBA
01/2014
1OsteoprotegerinIBA
01/2014
1Acute-Phase Proteins (Acute-Phase Protein)IBA
09/2013
1Antiphospholipid AntibodiesIBA
06/2013
1HLA Antigens (Human Leukocyte Antigens)IBA
06/2013

Therapy/Procedure

3Injections
10/2010 - 09/2006
2Remission Induction
08/2015 - 09/2012
1Activities of Daily Living (ADL)
07/2013