Ya-Ching Hsieh Selected Research

Hemorrhage

10/2008	Mechanism of estrogen-mediated improvement in cardiac function after trauma-hemorrhage: p38-dependent normalization of cardiac Akt phosphorylation and glycogen levels.
08/2008	The role of MIP-1alpha in the development of systemic inflammatory response and organ injury following trauma hemorrhage.
04/2008	Mitogen activated protein kinase (MAPK) mediates non-genomic pathway of estrogen on T cell cytokine production following trauma-hemorrhage.
03/2008	Estrogen-mediated activation of non-genomic pathway improves macrophages cytokine production following trauma-hemorrhage.
09/2007	Estrogen receptor-alpha predominantly mediates the salutary effects of 17beta-estradiol on splenic macrophages following trauma-hemorrhage.
09/2007	Mechanism of the nongenomic effects of estrogen on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of the PI-3K/Akt pathway.
06/2007	The role of estrogen receptor subtypes in ameliorating hepatic injury following trauma-hemorrhage.
06/2007	The PI3K/Akt pathway mediates the nongenomic cardioprotective effects of estrogen following trauma-hemorrhage.
06/2007	Role of p38 mitogen-activated protein kinase pathway in estrogen-mediated cardioprotection following trauma-hemorrhage.
06/2007	Salutary effects of 17beta-estradiol on T-cell signaling and cytokine production after trauma-hemorrhage are mediated primarily via estrogen receptor-alpha.
05/2007	Downregulation of migration inhibitory factor is critical for estrogen-mediated attenuation of lung tissue damage following trauma-hemorrhage.
05/2007	Downregulation of TLR4-dependent ATP production is critical for estrogen-mediated immunoprotection in Kupffer cells following trauma-hemorrhage.
04/2007	G protein-coupled receptor 30-dependent protein kinase A pathway is critical in nongenomic effects of estrogen in attenuating liver injury after trauma-hemorrhage.
03/2007	17Beta-estradiol downregulates Kupffer cell TLR4-dependent p38 MAPK pathway and normalizes inflammatory cytokine production following trauma-hemorrhage.
03/2007	Monocyte chemoattractant protein-1 influences trauma-hemorrhage-induced distal organ damage via regulation of keratinocyte-derived chemokine production.
02/2007	Flutamide attenuates pro-inflammatory cytokine production and hepatic injury following trauma-hemorrhage via estrogen receptor-related pathway.
01/2007	Tissue compartment-specific role of estrogen receptor subtypes in immune cell cytokine production following trauma-hemorrhage.
09/2006	Maintenance of lung myeloperoxidase activity in proestrus females after trauma-hemorrhage: upregulation of heme oxygenase-1.
09/2006	Upregulation of mitochondrial respiratory complex IV by estrogen receptor-beta is critical for inhibiting mitochondrial apoptotic signaling and restoring cardiac functions following trauma-hemorrhage.
08/2006	Androstenediol administration after trauma-hemorrhage attenuates inflammatory response, reduces organ damage, and improves survival following sepsis.
08/2006	17 beta-estradiol administration following trauma-hemorrhage prevents the increase in Kupffer cell cytokine production and MAPK activation predominately via estrogen receptor-alpha.
07/2006	A role of PPAR-gamma in androstenediol-mediated salutary effects on cardiac function following trauma-hemorrhage.
06/2006	Inhibition of cardiac PGC-1alpha expression abolishes ERbeta agonist-mediated cardioprotection following trauma-hemorrhage.
05/2006	Tissue-specific expression of estrogen receptors and their role in the regulation of neutrophil infiltration in various organs following trauma-hemorrhage.
05/2006	Salutary effects of estrogen receptor-beta agonist on lung injury after trauma-hemorrhage.
02/2006	Mechanism of the salutary effects of flutamide on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of estrogen receptor-{beta}-dependent HO-1.
01/2006	Flutamide restores cardiac function after trauma-hemorrhage via an estrogen-dependent pathway through upregulation of PGC-1.
12/2005	PGC-1 upregulation via estrogen receptors: a common mechanism of salutary effects of estrogen and flutamide on heart function after trauma-hemorrhage.
08/2005	Salutary effects of androstenediol on hepatic function after trauma-hemorrhage are mediated via peroxisome proliferators-activated receptor gamma.

Articles by Research Topic

Disease

32	Wounds and Injuries (Trauma) 10/2008 - 07/2005
29	Hemorrhage 10/2008 - 08/2005
3	Sepsis (Septicemia) 09/2007 - 10/2005
2	Hemorrhagic Shock 01/2006 - 07/2005
1	Shock 01/2006

Drug/Important Bio-Agent (IBA)

14	Estrogens (Estrogen)FDA Link 10/2008 - 12/2005
5	Flutamide (Eulexin)FDA LinkGeneric 02/2007 - 07/2005
5	Estrogen Receptor betaIBA 09/2006 - 01/2006
3	Peroxidase (Myeloperoxidase)IBA 09/2007 - 02/2006
3	Estrogen Receptor alphaIBA 09/2007 - 08/2006
3	AndrostenediolIBA 08/2006 - 08/2005
3	Estrogen ReceptorsIBA 05/2006 - 07/2005
2	Protein Kinases (Protein Kinase)IBA 04/2008 - 06/2007
1	GlycogenIBA 10/2008
1	Chemokine CCL3IBA 08/2008
1	Gonadal Steroid Hormones (Sex Hormones)IBA 09/2007
1	Adenosine Triphosphate (ATP)IBA 05/2007
1	GTP-Binding Proteins (G-Protein)IBA 04/2007
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 04/2007
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 03/2007
1	p38 Mitogen-Activated Protein KinasesIBA 03/2007
1	Heme Oxygenase-1IBA 09/2006
1	Estradiol (Estrace)FDA LinkGeneric 08/2006
1	PPAR gammaIBA 07/2006
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2006
1	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 10/2005
1	Protein Kinase C-alphaIBA 10/2005
1	Peroxisome ProliferatorsIBA 08/2005