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Gabriel N Hortobagyi Selected Research

Fluorouracil (Carac)

3/2012Phase III trial evaluating weekly paclitaxel versus docetaxel in combination with capecitabine in operable breast cancer.
8/2011Dual targeting of tumor angiogenesis and chemotherapy by endostatin-cytosine deaminase-uracil phosphoribosyltransferase.
1/2011Phase III randomized trial of dose intensive neoadjuvant chemotherapy with or without G-CSF in locally advanced breast cancer: long-term results.
11/2010Evaluation of a 30-gene paclitaxel, fluorouracil, doxorubicin, and cyclophosphamide chemotherapy response predictor in a multicenter randomized trial in breast cancer.
6/2010Clinical evaluation of chemotherapy response predictors developed from breast cancer cell lines.
5/2010A phase 2 study of a fixed combination of uracil and ftorafur and leucovorin given orally in a twice-daily regimen to treat patients with recurrent metastatic breast cancer.
3/2010A phase 2 study of a fixed combination of uracil and ftorafur (UFT) and leucovorin given orally in a 3-times-daily regimen to treat patients with recurrent metastatic breast cancer.
3/2010Phase 2 trial of primary systemic therapy with doxorubicin and docetaxel followed by surgery, radiotherapy, and adjuvant chemotherapy with cyclophosphamide, methotrexate, and 5-fluorouracil based on clinical and pathologic response in patients with stage IIB to III breast cancer : long-term results from the University of Texas M. D. Anderson Cancer Center Study ID97-099.
1/2010Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial.
6/2008Limits of observational data in determining outcomes from cancer therapy.
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Gabriel N Hortobagyi Research Topics

Disease

274Breast Neoplasms (Breast Cancer)
12/2013 - 01/2002
176Neoplasms (Cancer)
12/2013 - 01/2002
43Neoplasm Metastasis (Metastasis)
12/2013 - 06/2002
26Carcinoma (Carcinomatosis)
06/2007 - 05/2002
13Disease Progression
05/2013 - 04/2002
9Inflammatory Breast Neoplasms
11/2013 - 02/2004
8Residual Neoplasm
02/2012 - 04/2004
7Neutropenia
05/2012 - 01/2003
6Circulating Neoplastic Cells
01/2012 - 04/2009
5Heart Failure
11/2013 - 11/2002
4Infection
05/2012 - 10/2002
4Noninfiltrating Intraductal Carcinoma (DCIS)
02/2012 - 06/2002
4Pancreatic Neoplasms (Pancreatic Cancer)
01/2011 - 10/2002
3Hypertension (High Blood Pressure)
11/2013 - 09/2007
3Ovarian Neoplasms (Ovarian Cancer)
06/2013 - 11/2002
3Male Breast Neoplasms (Male Breast Cancer)
05/2013 - 06/2002
3Hypersensitivity (Allergy)
01/2013 - 05/2002
3Pneumonia (Pneumonitis)
02/2012 - 07/2002
2Coronary Artery Disease (Coronary Atherosclerosis)
11/2013 - 09/2007
2Peripheral Nervous System Diseases (PNS Diseases)
07/2013 - 11/2012
2Overweight
01/2013 - 01/2011
2Obesity
10/2012 - 09/2008
2Fatigue
02/2012 - 02/2004
2Anemia
02/2012 - 05/2009
2Lymphatic Diseases (Lymphadenopathy)
09/2011 - 04/2011

Drug/Important Bio-Agent (IBA)

53Estrogens (Estrogen)FDA Link
05/2013 - 01/2002
51HormonesIBA
12/2013 - 10/2002
41Doxorubicin (Adriamycin)FDA LinkGeneric
12/2011 - 01/2002
37Cyclophosphamide (Cytoxan)FDA LinkGeneric
03/2012 - 01/2002
36trastuzumab (Herceptin)FDA Link
11/2013 - 04/2002
35Epidermal Growth Factor Receptor (EGF Receptor)IBA
05/2013 - 10/2002
34Paclitaxel (Taxol)FDA LinkGeneric
06/2013 - 05/2002
32Fluorouracil (Carac)FDA LinkGeneric
03/2012 - 01/2002
27taxaneIBA
07/2013 - 02/2002
20Progesterone Receptors (Progesterone Receptor)IBA
05/2013 - 10/2002
17docetaxel (Taxotere)FDA Link
05/2012 - 01/2002
16Biological Markers (Surrogate Marker)IBA
12/2013 - 06/2002
15TamoxifenFDA LinkGeneric
02/2012 - 01/2002
14DNA (Deoxyribonucleic Acid)IBA
12/2013 - 12/2006
14Phosphotransferases (Kinase)IBA
11/2013 - 05/2003
14TaxoidsIBA
01/2013 - 05/2002
12AnthracyclinesIBA
06/2012 - 09/2003
10exemestane (Aromasin)FDA Link
12/2013 - 03/2004
10Aromatase (CYP19)IBA
12/2013 - 03/2004
10everolimusFDA Link
12/2013 - 10/2007
9capecitabine (Xeloda)FDA Link
03/2012 - 09/2003
9Messenger RNA (mRNA)IBA
03/2012 - 06/2005
9Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2011 - 06/2003
8Proteins (Proteins, Gene)IBA
01/2013 - 09/2003
7lapatinib (GW572016)FDA Link
04/2013 - 07/2008
6Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2012 - 08/2007
6DiphosphonatesIBA
04/2012 - 10/2003
6Epirubicin (Ellence)FDA LinkGeneric
03/2012 - 06/2005
6Transcription Factors (Transcription Factor)IBA
02/2012 - 09/2003
6bevacizumabFDA Link
08/2011 - 10/2004
5ParaffinIBA
01/2013 - 04/2004
5anastrozole (Arimidex)FDA LinkGeneric
08/2012 - 06/2002
5Granulocyte Colony-Stimulating Factor (G-CSF)IBA
03/2011 - 01/2002
5erlotinib (CP 358,774)FDA Link
01/2011 - 06/2007
5Estrogen ReceptorsIBA
12/2006 - 05/2002
4Epidermal Growth Factor (EGF)IBA
08/2013 - 10/2007
4Aromatase InhibitorsIBA
05/2013 - 02/2012
4ixabepilone (BMS 247550)FDA Link
11/2012 - 08/2007
4Cyclin D1IBA
05/2010 - 10/2002
3RNA (Ribonucleic Acid)IBA
12/2013 - 06/2003
3CyclinsIBA
01/2013 - 10/2006
3Metformin (Glucophage)FDA LinkGeneric
01/2013 - 07/2009
3Protein Kinases (Protein Kinase)IBA
09/2012 - 02/2004
3zoledronic acid (zoledronate)FDA Link
04/2012 - 01/2005
3Selective Estrogen Receptor Modulators (SERM)IBA
02/2012 - 03/2004
3vinorelbine (Navelbine)FDA LinkGeneric
11/2011 - 01/2002
3gemcitabineFDA Link
01/2011 - 05/2002
3CytotoxinsIBA
01/2011 - 05/2002
3Phenobarbital (Luminal)FDA Link
01/2011 - 08/2005
3Leucovorin (Folinic Acid)FDA Link
05/2010 - 06/2004
3thymidine 5'-triphosphate (TTP)IBA
05/2010 - 09/2004
3Cadherins (E-Cadherin)IBA
05/2010 - 12/2006
3Methotrexate (Mexate)FDA LinkGeneric
03/2010 - 11/2003
3tau Proteins (tau Protein)IBA
09/2009 - 06/2005
3Biological Tumor Markers (Tumor Markers)IBA
01/2008 - 10/2002
3Cyclin EIBA
01/2007 - 11/2002
2Sirolimus (Rapamycin)FDA Link
08/2013 - 02/2012
2Formaldehyde (Formol)FDA Link
01/2013 - 05/2005
2triciribineIBA
09/2012 - 10/2007
2pamidronate (APD)FDA LinkGeneric
04/2012 - 06/2008
2Filgrastim (Neupogen)FDA Link
11/2011 - 07/2003
2ErythropoietinFDA Link
08/2011 - 11/2010
2Cytosine DeaminaseIBA
08/2011 - 01/2006

Therapy/Procedure

154Drug Therapy (Chemotherapy)
11/2013 - 01/2002
25Adjuvant Chemotherapy
03/2012 - 01/2002
20Radiotherapy
09/2011 - 06/2002
17Mastectomy (Mammectomy)
09/2011 - 01/2002
16Neoadjuvant Therapy
01/2013 - 10/2002
8Heterologous Transplantation (Xenotransplantation)
10/2012 - 10/2002
6Aftercare (After-Treatment)
12/2013 - 07/2002
4Segmental Mastectomy (Lumpectomy)
10/2009 - 07/2002
3Hematopoietic Stem Cell Transplantation
01/2012 - 11/2004
3Combination Drug Therapy (Combination Chemotherapy)
05/2011 - 02/2006
2Chemoprevention
02/2012 - 06/2002
2Therapeutics
01/2012 - 10/2004