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Gabriel N Hortobagyi Selected Research

Carcinoma (Carcinomatosis)

06/2007Pilot study of regional, hepatic intra-arterial paclitaxel in patients with breast carcinoma metastatic to the liver.
09/2006Phase I study of capecitabine in combination with temozolomide in the treatment of patients with brain metastases from breast carcinoma.
06/2006Randomized trial of high-dose chemotherapy and autologous hematopoietic stem cell support for high-risk primary breast carcinoma: follow-up at 12 years.
08/2005Phase II study of tariquidar, a selective P-glycoprotein inhibitor, in patients with chemotherapy-resistant, advanced breast carcinoma.
08/2005Epidermal growth factor receptor expression correlates with poor survival in patients who have breast carcinoma treated with doxorubicin-based neoadjuvant chemotherapy.
03/2005Thyroid hormone and breast carcinoma. Primary hypothyroidism is associated with a reduced incidence of primary breast carcinoma.
10/2004Colitis in patients with breast carcinoma treated with taxane-based chemotherapy.
07/2004Lack of association between amplification of her-2 and response to preoperative taxanes in patients with breast carcinoma.
07/2004Proceedings of the consensus conference on neoadjuvant chemotherapy in carcinoma of the breast, April 26-28, 2003, Philadelphia, PA.
06/2004Proceedings of the consensus conference on neoadjuvant chemotherapy in carcinoma of the breast, April 26-28, 2003, Philadelphia, Pennsylvania.
05/2004Pharmacoproteomic analysis of prechemotherapy and postchemotherapy plasma samples from patients receiving neoadjuvant or adjuvant chemotherapy for breast carcinoma.
04/2004Change in tumor cellularity of breast carcinoma after neoadjuvant chemotherapy as a variable in the pathologic assessment of response.
02/2004Prognostic significance of phosphorylated P38 mitogen-activated protein kinase and HER-2 expression in lymph node-positive breast carcinoma.
02/2004Effects of pregnancy after treatment for breast carcinoma on survival and risk of recurrence.
09/2003Neoadjuvant chemotherapy for breast carcinoma: multidisciplinary considerations of benefits and risks.
09/2003A Phase II study of intravenous exatecan mesylate (DX-8951f) administered daily for 5 days every 3 weeks to patients with metastatic breast carcinoma.
07/2003Targeted filgrastim support in patients with early-stage breast carcinoma: toward the implementation of a risk model.
06/2003Total RNA yield and microarray gene expression profiles from fine-needle aspiration biopsy and core-needle biopsy samples of breast carcinoma.
04/2003Correlation between HER-2 expression and response to neoadjuvant chemotherapy with 5-fluorouracil, doxorubicin, and cyclophosphamide in patients with breast carcinoma.
11/2002Estrogen replacement therapy for menopausal women with a history of breast carcinoma: results of a 5-year, prospective study.
06/2002Assessment of histologic features and expression of biomarkers in predicting pathologic response to anthracycline-based neoadjuvant chemotherapy in patients with breast carcinoma.
05/2002Phase I study of eniluracil and oral 5-fluorouracil in combination with docetaxel in the treatment of patients with metastatic breast carcinoma.

Articles by Research Topic

Disease

96Breast Neoplasms (Breast Cancer)
10/2008 - 01/2002
22Carcinoma (Carcinomatosis)
06/2007 - 05/2002
16Neoplasms (Cancer)
06/2008 - 06/2002
6Neoplasm Metastasis (Metastasis)
01/2008 - 08/2005
2Residual Neoplasm
07/2007 - 10/2006
2Lobular Carcinoma
12/2006 - 01/2005
2Male Breast Neoplasms (Male Breast Cancer)
07/2006 - 06/2002
1Obesity
09/2008
1Pancreatic Neoplasms (Pancreatic Cancer)
09/2008
1Osteonecrosis (Kienbock's Disease)
06/2008
1Phyllodes Tumor (Cystosarcoma Phylloides)
11/2007
1Heart Failure
09/2007
1Inflammation
08/2007
1Noninfiltrating Intraductal Carcinoma (DCIS)
07/2007
1Ductal Carcinoma
12/2006
1Vasculitis (Vasculitides)
07/2006
1Death (Near-Death Experience)
03/2005
1Pneumonia (Pneumonitis)
11/2004
1Colitis
10/2004
1Neutropenia
01/2003
1Ovarian Neoplasms (Ovarian Cancer)
11/2002
1Pathologic Constriction (Stenosis)
06/2002

Drug/Important Bio-Agent (IBA)

13Paclitaxel (Taxol)FDA LinkGeneric
03/2008 - 05/2002
13Doxorubicin (Adriamycin)FDA LinkGeneric
11/2007 - 01/2002
9docetaxel (Taxotere)FDA Link
06/2008 - 01/2002
7trastuzumab (Herceptin)FDA Link
01/2007 - 04/2002
7Fluorouracil (Carac)FDA LinkGeneric
01/2007 - 01/2002
7Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2007 - 01/2002
6Biological Markers (Surrogate Marker)IBA
12/2006 - 06/2002
5Estrogens (Estrogen)FDA Link
10/2008 - 07/2003
4Epidermal Growth Factor Receptor (EGF Receptor)IBA
10/2007 - 06/2005
4taxaneIBA
08/2007 - 02/2002
3capecitabine (Xeloda)FDA Link
08/2007 - 09/2003
3Epirubicin (Ellence)FDA LinkGeneric
01/2007 - 06/2005
2DiphosphonatesIBA
06/2008 - 05/2008
2erlotinib (CP 358,774)FDA Link
08/2007 - 06/2007
2HormonesIBA
05/2007 - 03/2005
2tau Proteins (tau Protein)IBA
04/2007 - 06/2005
2TamoxifenFDA LinkGeneric
07/2006 - 01/2002
2gemcitabineFDA Link
09/2003 - 05/2002
2vinorelbine (Navelbine)FDA LinkGeneric
05/2002 - 01/2002
25-ethynyluracil (eniluracil)IBA
05/2002 - 02/2002
1Lysine (L-Lysine)FDA Link
09/2008
1Histones (Histone)IBA
09/2008
1lapatinib (GW572016)FDA Link
07/2008
1Cisplatin (Platino)FDA LinkGeneric
05/2008
1Dacarbazine (DIC)FDA LinkGeneric
11/2007
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
10/2007
1ixabepilone (BMS 247550)FDA Link
08/2007
1I-kappa B KinaseIBA
08/2007
1Cyclin-Dependent Kinase 2IBA
08/2007
1DNA (Deoxyribonucleic Acid)IBA
12/2006
1CyclinsIBA
10/2006
1Phosphotransferases (Kinase)IBA
10/2006
1temozolomide (Temodar)FDA Link
09/2006
1Aromatase (CYP19)IBA
07/2006
1Leuprolide (Lupron)FDA LinkGeneric
07/2006
1Cytosine DeaminaseIBA
01/2006
1EndostatinsIBA
01/2006
1Transcription Factors (Transcription Factor)IBA
12/2005
1ParaffinIBA
10/2005
1albumin-bound paclitaxelFDA Link
09/2005
1tariquidar (XR9576)IBA
08/2005
1P-GlycoproteinIBA
08/2005
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
05/2005
1Carmustine (FIVB)FDA Link
11/2004
1Thiotepa (Triethylenethiophosphoramide)FDA LinkGeneric
11/2004
1TaxoidsIBA
07/2004
1Protein Kinases (Protein Kinase)IBA
02/2004
1Proteins (Proteins, Gene)IBA
01/2004
1fludarabineIBA
11/2003
1Melphalan (Alkeran)FDA Link
11/2003
1NF-kappa B (NF-kB)IBA
11/2003
1sulindac sulfone (exisulind)IBA
09/2003
1pegylated liposomal doxorubicinIBA
09/2003
1DX 8951 (DX 8951f)IBA
09/2003
1Filgrastim (Neupogen)FDA Link
07/2003
1RNA (Ribonucleic Acid)IBA
06/2003
1bexarotene (LGD1069)FDA Link
03/2003
1Estrogen ReceptorsIBA
03/2003
1Cyclin EIBA
11/2002
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
11/2002
1Luteinizing Hormone (Lutropin)FDA LinkGeneric
11/2002
1annamycinIBA
07/2002
1anastrozole (Arimidex)FDA Link
06/2002
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
01/2002

Therapy/Procedure

55Drug Therapy (Chemotherapy)
09/2008 - 06/2002
9Adjuvant Chemotherapy
10/2008 - 05/2002
6Mastectomy (Mammectomy)
12/2006 - 07/2002
5Neoadjuvant Therapy
03/2008 - 06/2005
2Adjuvant Radiotherapy
10/2005 - 03/2005
1Biological Therapy
05/2007
1Hematopoietic Stem Cell Transplantation
11/2004
1Aftercare (After-Treatment)
02/2004
1Stem Cell Transplantation
11/2003
1Estrogen Replacement Therapy
11/2002