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Rikard Holmdahl Selected Research

Rheumatoid Arthritis

1/2016Ncf1 polymorphism reveals oxidative regulation of autoimmune chronic inflammation.
8/2015B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production.
6/2015Hydroxyethylene isosteres introduced in type II collagen fragments substantially alter the structure and dynamics of class II MHC A(q)/glycopeptide complexes.
2/2015Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins.
1/2015Anti-carbamylated protein antibodies in the pre-symptomatic phase of rheumatoid arthritis, their relationship with multiple anti-citrulline peptide antibodies and association with radiological damage.
1/2015Associations of antibodies against citrullinated peptides with human leukocyte antigen-shared epitope and smoking prior to the development of rheumatoid arthritis.
8/2014Citrullination of collagen II affects integrin-mediated cell adhesion in a receptor-specific manner.
6/2014Identification of new citrulline-specific autoantibodies, which bind to human arthritic cartilage, by mass spectrometric analysis of citrullinated type II collagen.
1/2014Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint.
1/2014Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis.
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Rikard Holmdahl Research Topics

Disease

118Arthritis (Polyarthritis)
01/2016 - 01/2002
79Rheumatoid Arthritis
01/2016 - 02/2002
59Experimental Arthritis
08/2015 - 05/2002
32Inflammation
08/2015 - 01/2002
17Autoimmune Diseases (Autoimmune Disease)
08/2015 - 01/2002
6Psoriasis (Pustulosis Palmaris et Plantaris)
01/2016 - 10/2006
5Chronic Granulomatous Disease
12/2014 - 11/2012
5Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
07/2010 - 07/2002
4Multiple Sclerosis
01/2016 - 01/2003
4Neoplasms (Cancer)
01/2015 - 10/2010
4Systemic Lupus Erythematosus (Libman-Sacks Disease)
12/2014 - 09/2002
4Hypersensitivity (Allergy)
12/2012 - 08/2004
4Relapsing Polychondritis
03/2004 - 01/2002
3Infection
12/2014 - 04/2013
3Necrosis
08/2010 - 08/2005
2Gout
01/2016 - 05/2014
2Colitis
08/2014 - 01/2014
2Pathologic Processes
11/2011 - 01/2010
2Osteoarthritis
01/2011 - 09/2002
2Skin Diseases
04/2008 - 10/2006
2Demyelinating Diseases (Demyelinating Disease)
03/2003 - 07/2002
1Fatty Liver
02/2015
1Alcoholic Fatty Liver
02/2015
1Sarcoma (Soft Tissue Sarcoma)
01/2015
1Emphysema
01/2015

Drug/Important Bio-Agent (IBA)

71Collagen Type II (Type II Collagen)IBA
08/2015 - 01/2002
43AntibodiesIBA
08/2015 - 09/2002
32CollagenIBA
08/2014 - 01/2002
25pristane (pristan)IBA
03/2015 - 01/2002
23Reactive Oxygen Species (Oxygen Radicals)IBA
08/2015 - 09/2005
20NADPH Oxidase (NAD(P)H oxidase)IBA
01/2016 - 01/2003
18Immunoglobulin G (IgG)IBA
12/2014 - 09/2002
15AntigensIBA
08/2015 - 08/2005
13Proteins (Proteins, Gene)IBA
01/2015 - 01/2002
12AutoantibodiesIBA
08/2015 - 09/2002
11PeptidesIBA
06/2015 - 05/2007
11Monoclonal AntibodiesIBA
06/2011 - 09/2002
9EpitopesIBA
01/2014 - 09/2002
7neutrophil cytosolic factor 1IBA
01/2012 - 01/2003
6acetyl 4-aminosalicylic acidIBA
02/2015 - 01/2010
6cartilage matrix proteinIBA
09/2013 - 01/2002
6T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA
07/2013 - 06/2002
5CytokinesIBA
05/2014 - 01/2004
5Complement System Proteins (Complement)IBA
10/2013 - 03/2004
4Antigen-Antibody Complex (Immune Complex)IBA
06/2013 - 07/2004
44- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA
11/2012 - 02/2007
4NADP (NADPH)IBA
07/2012 - 09/2005
4AutoantigensIBA
12/2011 - 01/2002
4GlycopeptidesIBA
01/2011 - 12/2002
3CitrullineIBA
01/2015 - 02/2009
3OxygenIBA
08/2014 - 08/2007
3Immunoglobulin M (IgM)IBA
07/2013 - 12/2003
3Mineral Oil (Liquid Paraffin)FDA LinkGeneric
12/2012 - 12/2007
3Toll-Like Receptors (Toll-Like Receptor)IBA
11/2011 - 01/2010
3T-Cell Antigen Receptors (T-Cell Receptor)IBA
11/2007 - 12/2002
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2006 - 02/2002
3oligodendrocyte-myelin glycoproteinIBA
08/2004 - 07/2002
2HLA-DR Antigens (HLA-DR)IBA
03/2015 - 08/2012
2HLA-DQ Antigens (HLA-DQ)IBA
03/2015 - 08/2012
2Toll-Like Receptor 2IBA
02/2015 - 07/2012
2L 012IBA
08/2014 - 09/2009
2NitrogenIBA
08/2014 - 09/2009
2Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)IBA
10/2013 - 01/2005
2Carbon MonoxideIBA
08/2013 - 01/2012
2poly(N-isopropylacrylamide)IBA
08/2013 - 11/2011
2PolymersIBA
08/2013 - 11/2011
2Peptide Hydrolases (Proteases)IBA
07/2013 - 01/2011
2AsparagineIBA
06/2013 - 10/2007
2Fibrinogen (Factor I)FDA Link
05/2013 - 01/2002
2Superoxides (Superoxide)IBA
04/2013 - 01/2012
2Proteoglycans (Proteoglycan)IBA
03/2013 - 06/2011
2Collagen Type XIIBA
08/2012 - 05/2002
2OvalbuminIBA
08/2011 - 09/2008
2Toll-Like Receptor 3IBA
01/2011 - 01/2010
2OxidoreductasesIBA
10/2010 - 09/2005
2Fc Receptors (Fc Receptor)IBA
05/2010 - 08/2003
2Estrogens (Estrogen)FDA Link
01/2010 - 11/2003
2Staphylococcal Protein A (A, Protein)IBA
09/2009 - 01/2005
2Rheumatoid FactorIBA
09/2008 - 12/2003
2Lysine (L-Lysine)FDA Link
08/2008 - 10/2004
2Freund's AdjuvantIBA
07/2008 - 05/2007
2IntegrinsIBA
04/2008 - 10/2006
2cryogelIBA
07/2007 - 01/2005
2Interferon-betaIBA
01/2007 - 12/2005
2PhytolIBA
01/2007 - 09/2006
2Glycoproteins (Glycoprotein)IBA
01/2007 - 01/2002
2Interleukin-4 (Interleukin 4)IBA
06/2006 - 10/2002
2Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
03/2006 - 03/2005
2glycosylated collagenIBA
02/2006 - 07/2002
2FibrinolysinFDA Link
08/2005 - 03/2005
2PlasminogenIBA
08/2005 - 03/2005
1B-Lymphocyte Epitopes (B-Cell Epitope)IBA
08/2015
1MicroRNAs (MicroRNA)IBA
02/2015
1MethylcholanthreneIBA
01/2015
1Pancreatic Elastase (Elastase)IBA
01/2015

Therapy/Procedure

3Injections
09/2014 - 03/2005
3Transplantation (Transplant Recipients)
10/2010 - 06/2002
2Subcutaneous Injections
01/2011 - 01/2007
2Intraperitoneal Injections
02/2007 - 09/2005
2Intravenous Injections
09/2005 - 07/2004