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Rikard Holmdahl Selected Research

Arthritis (Polyarthritis)

07/2008Cartilage oligomeric matrix protein induction of chronic arthritis in mice.
01/2008The role of collagen antibodies in mediating arthritis.
12/2007The Rheumatoid Arthritis-Associated Autoantigen hnRNP-A2 (RA33) Is a Major Stimulator of Autoimmunity in Rats with Pristane-Induced Arthritis.
10/2007Endoglycosidase treatment abrogates IgG arthritogenicity: importance of IgG glycosylation in arthritis.
10/2007Macrophages suppress T cell responses and arthritis development in mice by producing reactive oxygen species.
08/2007Lack of reactive oxygen species breaks T cell tolerance to collagen type II and allows development of arthritis in mice.
05/2007Quantitative structure-activity relationship of peptides binding to the class II major histocompatibility complex molecule Aq associated with autoimmune arthritis.
02/2007Type II collagen without adjuvant induces eosinophilic arthritis.
01/2007Ethanol prevents development of destructive arthritis.
01/2007Collagen antibody induced arthritis.
01/2007Arthritis suppression by NADPH activation operates through an interferon-beta pathway.
01/2007Arthritis induced with minor cartilage proteins.
01/2007Pristane-induced arthritis in the rat.
02/2006Therapeutic vaccination of active arthritis with a glycosylated collagen type II peptide in complex with MHC class II molecules.
01/2006Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity.
09/2005Efficient promotion of collagen antibody induced arthritis (CAIA) using four monoclonal antibodies specific for the major epitopes recognized in both collagen induced arthritis and rheumatoid arthritis.
03/2005The plasminogen activator/plasmin system is essential for development of the joint inflammatory phase of collagen type II-induced arthritis.
02/2005The major T cell epitope on type II collagen is glycosylated in normal cartilage but modified by arthritis in both rats and humans.
01/2005Induction of a B-cell-dependent chronic arthritis with glucose-6-phosphate isomerase.
07/2004Antileukoproteinase: modulation of neutrophil function and therapeutic effects on anti-type II collagen antibody-induced arthritis.
01/2004Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells.
12/2003Chronicity of pristane-induced arthritis in rats is controlled by genes on chromosome 14.
11/2003Collagen type II-specific monoclonal antibody-induced arthritis in mice: description of the disease and the influence of age, sex, and genes.
10/2003Genetic control of tolerance to type II collagen and development of arthritis in an autologous collagen-induced arthritis model.
08/2003A comparative genetic analysis between collagen-induced arthritis and pristane-induced arthritis.
08/2003Induction of arthritis by single monoclonal IgG anti-collagen type II antibodies and enhancement of arthritis in mice lacking inhibitory FcgammaRIIB.
07/2003Identification and isolation of dominant susceptibility loci for pristane-induced arthritis.
01/2003Differential gene expression in pristane-induced arthritis susceptible DA versus resistant E3 rats.
08/2002Both common and unique susceptibility genes in different rat strains with pristane-induced arthritis.
05/2002Immunization of rats with homologous type XI collagen leads to chronic and relapsing arthritis with different genetics and joint pathology than arthritis induced with homologous type II collagen.

Articles by Research Topic

Disease

30Arthritis (Polyarthritis)
07/2008 - 05/2002
12Rheumatoid Arthritis
12/2007 - 07/2002
12Experimental Arthritis
11/2007 - 06/2002
2Inflammation
04/2008 - 01/2008
2Relapsing Polychondritis
03/2004 - 01/2004
2Demyelinating Diseases (Demyelinating Disease)
03/2003 - 07/2002
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/2003 - 07/2002
1Bronchitis
09/2008
1Allergic Contact Dermatitis
08/2008
1Autoimmune Diseases (Autoimmune Disease)
07/2008
1Adult Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
04/2008
1Lyme Disease (Disease, Lyme)
09/2005

Drug/Important Bio-Agent (IBA)

17Collagen Type II (Type II Collagen)IBA
01/2008 - 05/2002
8AntibodiesIBA
01/2008 - 09/2002
7pristane (pristan)IBA
12/2007 - 08/2002
6CollagenIBA
08/2008 - 09/2003
4Immunoglobulin G (IgG)IBA
04/2008 - 08/2003
3Reactive Oxygen Species (Oxygen Radicals)IBA
10/2007 - 08/2007
2Rheumatoid FactorIBA
09/2008 - 12/2003
2PeptidesIBA
08/2008 - 05/2007
2cartilage matrix proteinIBA
07/2008 - 03/2004
2Complement System Proteins (Complement)IBA
01/2007 - 03/2004
2NADP (NADPH)IBA
01/2007 - 09/2005
2Interferon-betaIBA
01/2007 - 12/2005
2glycosylated collagenIBA
02/2006 - 07/2002
2EpitopesIBA
09/2005 - 01/2005
2T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA
02/2005 - 06/2002
2oligodendrocyte-myelin glycoproteinIBA
01/2003 - 07/2002
1interleukin-21 (interleukin 21)IBA
07/2008
1Toll-Like Receptor 4IBA
04/2008
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
11/2007
1Ethanol (Ethyl Alcohol)IBA
01/2007
1Proteins (Proteins, Gene)IBA
01/2007
1NADPH Oxidase (NAD(P)H oxidase)IBA
01/2007
1Collagen Type IXIBA
01/2006
1HLA-DRB1 antigen (HLA DRB1)IBA
01/2006
1Protein Tyrosine PhosphatasesIBA
01/2006
1Monoclonal AntibodiesIBA
09/2005
1OxidoreductasesIBA
09/2005
1PlasminogenIBA
08/2005
1Plasminogen Activators (Plasminogen Activator)IBA
03/2005
1Plasmin (Fibrinolysin)FDA Link
03/2005
1PerforinIBA
01/2005
1Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)IBA
01/2005
1Interleukin-10 (Interleukin 10)IBA
01/2004
1GlycopeptidesIBA
09/2003
1OsteopontinIBA
03/2003
1Collagen Type XIIBA
05/2002

Therapy/Procedure

1Transplantation (Transplant Recipients)
06/2002