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John B Holcomb Selected Research

Resuscitation

09/2008	Thrombelastography is Better Than PT, aPTT, and Activated Clotting Time in Detecting Clinically Relevant Clotting Abnormalities After Hypothermia, Hemorrhagic Shock and Resuscitation in Pigs.
05/2008	Effects of synthetic versus natural colloid resuscitation on inducing dilutional coagulopathy and increasing hemorrhage in rabbits.
04/2008	Closed-loop and decision-assist resuscitation of burn patients.
02/2008	Joint Theater Trauma System implementation of burn resuscitation guidelines improves outcomes in severely burned military casualties.
02/2007	Damage control resuscitation: directly addressing the early coagulopathy of trauma.
09/2006	Evolution of burn resuscitation in operation Iraqi freedom.
05/2006	Damage control resuscitation: the need for specific blood products to treat the coagulopathy of trauma.
05/2006	Base deficit and alveolar-arterial gradient during resuscitation contribute independently but modestly to the prediction of mortality after burn injury.
07/2005	Endpoints in clinical trials of fluid resuscitation of patients with traumatic injuries.
12/2002	Secondary abdominal compartment syndrome is an elusive early complication of traumatic shock resuscitation.
06/2002	Evaluation of trauma team performance using an advanced human patient simulator for resuscitation training.
06/2002	Scientific priorities and strategic planning for resuscitation research and life saving therapy following traumatic injury: report of the PULSE Trauma Work Group.
03/2002	Scientific priorities and strategic planning for resuscitation research and life saving therapy following traumatic injury: report of the PULSE Trauma Work Group. Post Resuscitative and Initial Utility of Life Saving Efforts.

Articles by Research Topic

Disease

19	Wounds and Injuries (Trauma) 02/2008 - 03/2002
8	Hemorrhage 06/2008 - 07/2003
5	Burns 09/2008 - 05/2006
1	Hypothermia 09/2008
1	Hemorrhagic Shock 09/2008
1	Acidosis 11/2007
1	Pressure Ulcer (Bedsore) 01/2007
1	Intracranial Hemorrhages (Intracranial Hemorrhage) 09/2006
1	Traumatic Shock 12/2002
1	Compartment Syndromes (Compartment Syndrome) 12/2002

Drug/Important Bio-Agent (IBA)

9	recombinant FVIIa (rFVIIa)IBA 06/2008 - 08/2002
4	Factor VIIa (Activated Factor VII)IBA 02/2008 - 01/2005
2	Insulin (Novolin)FDA Link 09/2008 - 12/2007
2	Fibrinogen (Factor I)IBA 11/2007 - 11/2005
1	Glucose (Dextrose)FDA LinkGeneric 09/2008
1	Colloids (Colloid)IBA 05/2008
1	Transcription Factors (Transcription Factor)IBA 07/2003

Therapy/Procedure

13	Resuscitation 09/2008 - 03/2002
2	Tourniquets 02/2008 - 02/2008
1	Blood Transfusion (Blood Transfusions) 09/2008
1	Erythrocyte Transfusion 02/2008
1	Transplants (Transplant) 01/2007
1	Critical Care 01/2005