SearchDictionaryMobileLogin

Kosei Hirakawa Selected Research

Neoplasm Metastasis (Metastasis)

03/2008Combination therapy of S-1 with selective cyclooxygenase-2 inhibitor for liver metastasis of colorectal carcinoma.
11/2007Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via reduction of lymphangiogenesis.
08/2007A synergistic antitumor effect of interleukin-2 addition with CD80 immunogene therapy for peritoneal metastasis of gastric carcinoma.
12/2006A synergic inhibitory-effect of combination with selective cyclooxygenase-2 inhibitor and S-1 on the peritoneal metastasis for scirrhous gastric cancer cells.
12/2005Plasminogen activator inhibitor-1 (PAI-1) gene transfection inhibits the liver metastasis of pancreatic cancer by preventing angiogenesis.
08/2005Up regulation of ICAM-1 gene expression inhibits tumour growth and liver metastasis in colorectal carcinoma.
05/2005[A case of anthracycline and taxane-resistant breast cancer with life-thereatening multiple liver metastases responding to oral combination chemotherapy by UFT, cyclophosphamide and medroxyprogesterone acetate]
02/2004[A case of gastric cancer with umbilical metastasis that responded to TS-1 with low-dose cis-platinum]
01/2004Combined treatment with selective cyclooxygenase-2 inhibitor and fluorinated pyrimidines for liver metastasis of colon cancer.
12/2003Identification of a trypsinogen activity stimulating factor produced by pancreatic cancer cells: its role in tumor invasion and metastasis.
10/2003[Validity of two-hour continuous hepatic arterial infusion chemotherapy with low-dose 5-FU for unresectable liver metastasis from colorectal cancer]
09/2003[Combined treatment with fluorinated pyrimidines and selective cyclooxygenase-2 inhibitors for liver metastasis of colon cancer]
01/2003Correlation between vascular endothelial growth factor C expression and lymph node metastasis in T1 carcinoma of the colon and rectum.
08/2002Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer.
05/2002Prognostic value of combined analysis of estrogen receptor status and cellular proliferative activity in breast cancer patients with extensive lymph node metastases.

Articles by Research Topic

Disease

15Neoplasm Metastasis (Metastasis)
03/2008 - 05/2002
14Stomach Neoplasms (Stomach Cancer)
12/2007 - 02/2004
7Carcinoma (Carcinomatosis)
05/2008 - 01/2003
7Neoplasms (Cancer)
11/2007 - 12/2003
7Pancreatic Neoplasms (Pancreatic Cancer)
01/2007 - 12/2003
6Colorectal Neoplasms (Colorectal Cancer)
03/2008 - 10/2003
5Colonic Neoplasms (Colon Cancer)
06/2008 - 08/2002
4Breast Neoplasms (Breast Cancer)
05/2005 - 05/2002
2Crohn Disease (Crohn's Disease)
09/2008 - 03/2008
2Esophageal Neoplasms (Esophageal Cancer)
09/2005 - 10/2003
1Ascites
11/2006
1Hyperaldosteronism (Conn Syndrome)
08/2006
1Atrophy
07/2006
1Infection
07/2006
1Microsatellite Instability
03/2006
1Thyroid Neoplasms (Thyroid Cancer)
12/2002

Drug/Important Bio-Agent (IBA)

6Cyclooxygenase 2 (Cyclooxygenase-2)IBA
03/2008 - 08/2002
5Cisplatin (Platino)FDA LinkGeneric
12/2007 - 02/2004
4Fluorouracil (Carac)FDA LinkGeneric
09/2005 - 10/2003
3titanium silicide (TS-1)IBA
07/2005 - 02/2004
2Epidermal Growth Factor Receptor (EGF Receptor)IBA
06/2008 - 02/2005
2pyrimidineIBA
12/2007 - 03/2004
2Ki23057IBA
11/2007 - 11/2006
2Vascular Endothelial Growth Factor CIBA
06/2007 - 01/2003
2Protease Inhibitors (Protease Inhibitor)IBA
01/2007 - 08/2004
2gemcitabineFDA Link
08/2006 - 06/2005
2trastuzumab (Herceptin)FDA Link
08/2006 - 10/2003
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
05/2005 - 07/2003
2Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA
11/2004 - 01/2004
2Estrogens (Estrogen)FDA Link
01/2004 - 05/2002
2PyrimidinesIBA
01/2004 - 09/2003
1GhrelinIBA
09/2008
1gefitinib (Iressa)FDA Link
06/2008
1Phosphotransferases (Kinase)IBA
05/2008
1Transforming Growth Factor beta Receptors (TGF beta Receptors)IBA
05/2008
1Endothelin Receptors (Endothelin Receptor)IBA
03/2008
1Endothelin-converting enzyme 1IBA
03/2008
1Histones (Histone)IBA
11/2007
1Interleukin-2 (IL2)IBA
08/2007
1Transforming Growth Factor beta (TGF-beta)IBA
02/2007
1EnzymesIBA
11/2006
1irinotecan (Camptosar)FDA LinkGeneric
11/2006
1Paclitaxel (Taxol)FDA LinkGeneric
11/2006
1DNA (Deoxyribonucleic Acid)IBA
09/2006
1Histone Deacetylases (Histone Deacetylase)IBA
09/2006
1trichostatin A (A 300)IBA
09/2006
1Pepsinogen A (Pepsinogen)IBA
07/2006
1MucinsIBA
01/2006
1Plasminogen Activators (Plasminogen Activator)IBA
12/2005
1InterferonsIBA
09/2005
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
08/2005
1docetaxel (Taxotere)FDA Link
07/2005
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
07/2005
1taxaneIBA
05/2005
1Medroxyprogesterone 17-Acetate (Depo-Provera)FDA LinkGeneric
05/2005
1Coenzyme A (CoA)IBA
07/2004
1monoacetoacetinIBA
07/2004
1succinyl-coenzyme A (succinyl-CoA)IBA
07/2004
1TransferasesIBA
07/2004
1Telomerase (Telomerase Reverse Transcriptase)IBA
01/2004
1Progesterone Receptors (Progesterone Receptor)IBA
01/2004
1Fibroblast Growth Factor 7FDA Link
12/2003
1TrypsinogenIBA
12/2003
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
09/2003
1PPAR gammaIBA
12/2002

Therapy/Procedure

2Combination Drug Therapy (Combination Chemotherapy)
05/2005 - 07/2003
1Adrenalectomy
08/2006
1Gastroenterostomy
03/2006
1Gastrectomy
03/2006
1Immunotherapy
01/2006
1Drug Therapy (Chemotherapy)
10/2003