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Nuala A Helsby Selected Research

5- (N,N- bis(2- chloroethyl)amino)- 2,4- dinitrobenzamide

4/2003Effect of nitroreduction on the alkylating reactivity and cytotoxicity of the 2,4-dinitrobenzamide-5-aziridine CB 1954 and the corresponding nitrogen mustard SN 23862: distinct mechanisms of bioreductive activation.

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Nuala A Helsby Research Topics

Disease

6Neoplasms (Cancer)
05/2015 - 03/2002
2Infection
01/2014 - 10/2010
2Inflammation
04/2010 - 04/2009
2Crohn Disease (Crohn's Disease)
04/2010 - 04/2009
1African Trypanosomiasis (Nagana)
05/2015
1Lupus Nephritis
12/2010
1Interstitial Nephritis (Tubulointerstitial Nephritis)
05/2010
1Colitis
04/2010
1Anoxia (Hypoxia)
06/2007

Drug/Important Bio-Agent (IBA)

35-(1-aziridinyl)-2,4-dinitrobenzamideIBA
06/2004 - 03/2002
2Mechlorethamine (Nitrogen Mustard)FDA Link
05/2015 - 04/2003
2LuciferasesIBA
01/2014 - 10/2010
2Interleukin-10 (Interleukin 10)IBA
04/2010 - 04/2009
2ProdrugsIBA
06/2007 - 04/2003
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
12/2010
1Omeprazole (Esomeprazole)FDA LinkGeneric
05/2010
1alpha-hydroxyglutarateIBA
04/2010
12-hydroxyadipic acidIBA
04/2010
1xanthurenic acidIBA
04/2010
1glutaric acidIBA
04/2010
15-aminovaleric acidIBA
04/2010
1FucoseIBA
04/2010
1DNA (Deoxyribonucleic Acid)IBA
02/2008
1CytotoxinsIBA
02/2008
1OxidoreductasesIBA
02/2008
1NADPH-Ferrihemoprotein Reductase (Cytochrome P450 Reductase)IBA
06/2007
1OxygenIBA
06/2007
1Carbon MonoxideIBA
06/2007
1aziridine (ethyleneimine)IBA
04/2003
15- (N,N- bis(2- chloroethyl)amino)- 2,4- dinitrobenzamideIBA
04/2003

Therapy/Procedure

2Heterologous Transplantation (Xenotransplantation)
06/2004 - 03/2002
1Drug Therapy (Chemotherapy)
05/2015