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Hal K Hawkins Selected Research

Smoke

5/2014Tiotropium bromide suppresses smoke inhalation and burn injury-induced ERK 1/2 and SMAD 2/3 signaling in sheep bronchial submucosal glands.
3/2014Airway obstruction and bacterial invasion in autopsy tissue of pediatric burn victims.
7/2013Effect of bronchodilators on bronchial gland cell proliferation after inhalation and burn injury in sheep.
12/2012γ-tocopherol nebulization decreases oxidative stress, arginase activity, and collagen deposition after burn and smoke inhalation in the ovine model.
7/2012Assessment of combined muscarinic antagonist and fibrinolytic therapy for inhalation injury.
4/2012Nebulization with γ-tocopherol ameliorates acute lung injury after burn and smoke inhalation in the ovine model.
12/2011Direct delivery of low-dose 7-nitroindazole into the bronchial artery attenuates pulmonary pathophysiology after smoke inhalation and burn injury in an ovine model.
10/2011The Angiotensin-converting enzyme inhibitor captopril inhibits poly(adp-ribose) polymerase activation and exerts beneficial effects in an ovine model of burn and smoke injury.
5/2011Impact of bronchial circulation on bronchial exudates following combined burn and smoke inhalation injury in sheep.
2/2011The peroxynitrite catalyst WW-85 improves pulmonary function in ovine septic shock.
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Hal K Hawkins Research Topics

Disease

47Burns
11/2015 - 03/2003
25Acute Lung Injury
04/2012 - 09/2002
16Smoke Inhalation Injury
12/2012 - 07/2003
13Sepsis (Septicemia)
07/2014 - 09/2002
12Airway Obstruction (Choking)
03/2014 - 09/2003
11Inflammation
06/2014 - 02/2003
9Lung Injury
05/2011 - 03/2003
8Pneumonia (Pneumonitis)
11/2015 - 09/2002
8Wounds and Injuries (Trauma)
08/2015 - 09/2004
8Edema
02/2014 - 07/2002
6Pulmonary Edema
12/2012 - 07/2002
5Adult Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
04/2012 - 09/2007
3Septic Shock (Toxic Shock Syndrome)
02/2011 - 07/2003
3Cicatrix (Scar)
12/2009 - 04/2004
3Hypertrophic Cicatrix (Hypertrophic Scar)
12/2009 - 04/2004
2Necrotizing Enterocolitis
08/2011 - 08/2007
1Bone Resorption
06/2014
1Hematoma
02/2014
1Chorioamnionitis
02/2014
1Single Umbilical Artery
02/2014
1Infarction
02/2014
1Necrosis
02/2011
1Systemic Inflammatory Response Syndrome (Sepsis Syndrome)
02/2011
1Pancreatitis
02/2011
1Abdominal Pain (Pain, Abdominal)
02/2011
1Bronchial Spasm
12/2010
1Stroke (Strokes)
11/2009
1Hyperemia
07/2009

Drug/Important Bio-Agent (IBA)

42SmokeIBA
05/2014 - 09/2002
8Nitric Oxide (Nitrogen Monoxide)FDA Link
12/2011 - 09/2004
7CollagenIBA
12/2012 - 04/2004
63-nitrotyrosineIBA
02/2012 - 05/2006
6salicylhydroxamic acid (SHAM)IBA
10/2011 - 09/2004
5Peroxidase (Myeloperoxidase)IBA
02/2012 - 08/2008
4tranilast (N 5')IBA
03/2014 - 03/2003
3tiotropium (Spiriva)FDA Link
05/2014 - 12/2010
3ArginaseIBA
12/2012 - 03/2011
3Malondialdehyde (Propanedial)IBA
02/2012 - 02/2011
3Nitric Oxide Synthase (NO Synthase)IBA
12/2011 - 05/2006
3CytokinesIBA
11/2011 - 04/2004
3Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
10/2011 - 02/2004
3Peroxynitrous Acid (Peroxynitrite)IBA
02/2011 - 09/2004
3Superoxides (Superoxide)IBA
02/2011 - 03/2006
3Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA
03/2010 - 04/2008
3Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
01/2009 - 05/2006
2NitrogenIBA
06/2014 - 07/2007
2FibrinIBA
02/2014 - 01/2007
2Reactive Oxygen Species (Oxygen Radicals)IBA
12/2012 - 08/2011
2Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA
07/2012 - 12/2010
2Protein CIBA
02/2012 - 09/2006
2Ceftazidime (Fortum)FDA LinkGeneric
02/2012 - 07/2007
2drotrecogin alfa activated (Xigris)FDA Link
02/2012 - 09/2006
2NeuropeptidesIBA
12/2011 - 01/2008
27-nitroindazoleIBA
12/2011 - 04/2008
2N,N-dimethylarginine (asymmetric dimethylarginine)IBA
11/2011 - 03/2011
2GasesIBA
11/2009 - 05/2006
2Poly Adenosine Diphosphate RiboseIBA
01/2009 - 07/2003
2Heparin (Liquaemin)FDA LinkGeneric
04/2003 - 09/2002
1mitochondrial messenger RNAIBA
08/2015
1Arginine Vasopressin (Argipressin)IBA
07/2014
1HormonesIBA
07/2014
1Vasopressin Receptors (Arginine Vasopressin Receptor)IBA
07/2014
1Muscle Proteins (Muscle Protein)IBA
06/2014
1STF 62247IBA
06/2014
1pamidronate (APD)FDA LinkGeneric
06/2014
1Oil AIBA
05/2014
1Bronchodilator Agents (Bronchodilators)IBA
07/2013
1Reactive Nitrogen SpeciesIBA
12/2012
1dimethylarginineIBA
12/2012
1Tissue Plasminogen Activator (Alteplase)FDA Link
07/2012
1Ethanol (Ethyl Alcohol)IBA
04/2012
1NitritesIBA
11/2011
1NitratesIBA
11/2011
1Captopril (Capoten)FDA LinkGeneric
10/2011
1Transforming Growth Factors (Transforming Growth Factor)IBA
10/2011
1Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
10/2011
1Halothane (Fluothane)FDA Link
05/2011
1VivonexIBA
03/2011
1Dietary Fats (Ghee)IBA
03/2011
1AmylasesFDA Link
02/2011
1Lipase (Acid Lipase)FDA Link
02/2011
1Acetylcholine (Acetylcholine Chloride)FDA Link
12/2010
1CP 96345IBA
05/2010
1Substance PIBA
05/2010
1Collagen Type III (Type III Collagen)IBA
12/2009
1HydrogenIBA
11/2009
1SodiumIBA
11/2009
1Calcitonin Gene-Related PeptideIBA
07/2009
1BIBN 4096BSIBA
07/2009
1NF-kappa B (NF-kB)IBA
05/2009
1Protein Isoforms (Isoforms)IBA
03/2009

Therapy/Procedure

6Anesthesia
12/2012 - 03/2006
4Critical Care
11/2015 - 02/2003
3Mechanical Ventilators (Ventilator)
11/2015 - 03/2006
3Lasers (Laser)
05/2014 - 07/2004
3Resuscitation
01/2009 - 06/2006
2Transplants (Transplant)
05/2014 - 09/2008
2Tracheostomy
10/2011 - 06/2006
1Ligation
05/2011
1Tracheotomy
02/2011