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Dominik Hartl Selected Research

Chitinase

12/2015The role of chitin, chitinases, and chitinase-like proteins in pediatric lung diseases.
1/2014Airway, but not serum or urinary, levels of YKL-40 reflect inflammation in early cystic fibrosis lung disease.
6/2011Role of breast regression protein-39 in the pathogenesis of cigarette smoke-induced inflammation and emphysema.
1/2011The chitinase-like protein YKL-40 modulates cystic fibrosis lung disease.
2/2009Novel biomarkers in asthma: chemokines and chitinase-like proteins.
12/2008Chitin regulation of immune responses: an old molecule with new roles.
11/2008Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells.

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Dominik Hartl Research Topics

Disease

17Inflammation
01/2016 - 11/2007
16Lung Diseases (Lung Disease)
12/2015 - 12/2006
10Cystic Fibrosis (Mucoviscidosis)
12/2015 - 06/2006
10Asthma (Bronchial Asthma)
12/2015 - 04/2005
4Infection
01/2016 - 02/2013
4Chronic Granulomatous Disease
01/2012 - 10/2004
3Chronic Obstructive Pulmonary Disease (COPD)
06/2011 - 01/2011
2Melanoma (Melanoma, Malignant)
09/2015 - 02/2014
2Emphysema
11/2014 - 06/2011
2Neoplasms (Cancer)
12/2013 - 12/2008
2Metaplasia
03/2013 - 12/2008
2Whooping Cough (Pertussis)
01/2011 - 12/2008
2Interstitial Lung Diseases (Interstitial Lung Disease)
01/2010 - 01/2005
2Cough
05/2007 - 04/2005
2Hypersensitivity (Allergy)
12/2006 - 02/2006
1Bronchiectasis
07/2015
1Dehydration (Water Stress)
11/2014
1Autoimmune Diseases (Autoimmune Disease)
06/2014
1Colorectal Neoplasms (Colorectal Cancer)
12/2013
1Human Influenza (Influenza)
05/2011
1Edema
05/2011
1Disease Susceptibility (Diathesis)
09/2009
1Netherton Syndrome
09/2009
1Ichthyosis (Xeroderma)
09/2009
1Pneumonia (Pneumonitis)
12/2008
1Bacterial Pneumonia
02/2008
1Bacterial Infections (Bacterial Infection)
02/2008
1Gastroesophageal Reflux (GERD)
11/2007
1Brain Neoplasms (Brain Tumor)
01/2007
1Aspergillosis
12/2006
1Allergic Bronchopulmonary Aspergillosis
06/2006
1Fever (Fevers)
06/2006
1Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders)
11/2005

Drug/Important Bio-Agent (IBA)

7ChitinaseIBA
12/2015 - 11/2008
6ChemokinesIBA
12/2014 - 04/2005
5Toll-Like Receptors (Toll-Like Receptor)IBA
01/2016 - 02/2006
5Messenger RNA (mRNA)IBA
03/2013 - 02/2006
4Proteins (Proteins, Gene)IBA
12/2015 - 12/2008
4CytokinesIBA
12/2013 - 06/2006
3ChitinIBA
12/2015 - 09/2008
3NADPH Oxidase (NAD(P)H oxidase)IBA
01/2012 - 02/2008
3AntigensIBA
01/2011 - 12/2008
2Poly I-CIBA
01/2016 - 05/2011
2Biological Markers (Surrogate Marker)IBA
09/2015 - 02/2009
2Peptide Hydrolases (Proteases)IBA
07/2015 - 12/2007
2Leukocyte Elastase (Neutrophil Elastase)IBA
07/2015 - 01/2014
2SmokeIBA
11/2014 - 06/2011
2FlagellinIBA
12/2013 - 02/2013
2Transcription Factors (Transcription Factor)IBA
03/2013 - 05/2007
2Chemokine ReceptorsIBA
06/2012 - 02/2008
2IgA receptor (protein B)IBA
02/2011 - 01/2005
2Protein CIBA
01/2010 - 01/2005
2Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
12/2006 - 01/2005
1imiquimod (Aldara)FDA LinkGeneric
01/2016
1N-Formylmethionine Leucyl-PhenylalanineIBA
01/2016
1Oxidants (Oxidizing Agents)IBA
07/2015
1Pancreatic Elastase (Elastase)IBA
07/2015
1DNA (Deoxyribonucleic Acid)IBA
01/2015
1Matrix Metalloproteinase 12IBA
11/2014
1Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA
10/2014
1Pattern Recognition ReceptorsIBA
06/2014
1marenostrin (pyrin)IBA
02/2014
1InflammasomesIBA
02/2014
1Toll-Like Receptor 5IBA
12/2013
1Acetyl Coenzyme A (Acetyl-CoA)IBA
12/2013
1Interleukin-6 (Interleukin 6)IBA
12/2013
1Glutathione (Reduced Glutathione)IBA
07/2013
1Staphylococcal Protein A (A, Protein)IBA
01/2013
1InterferonsIBA
01/2013
1Niacinamide (Nicotinamide)FDA LinkGeneric
01/2012
1MucinsIBA
05/2011
1Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
05/2011
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2011
1Focal Adhesion Protein-Tyrosine KinasesIBA
05/2011
1VaccinesIBA
01/2011
1Acellular VaccinesIBA
01/2011
1FibrinIBA
08/2010
1Immunoglobulins (Immunoglobulin)IBA
09/2009
1Serine Proteases (Serine Protease)IBA
09/2009
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
05/2009
1Pertussis VaccineIBA
12/2008
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
12/2008
1Interleukin-11 (Interleukin 11)IBA
12/2008
1Interleukin-13IBA
12/2008
1Immunoglobulin E (IgE)IBA
12/2008
1Interleukin-17 (Interleukin 27)IBA
09/2008
1NADP (NADPH)IBA
02/2008
1Complement Receptors (Complement Receptor)IBA
02/2008
1Toll-Like Receptor 2IBA
12/2007
1Interleukin-8 (Interleukin 8)IBA
12/2007
1Bile Acids and Salts (Bile Acids)IBA
11/2007
1Pepsin A (Pepsin)IBA
11/2007
1Cysteine (L-Cysteine)FDA Link
01/2007
1Scavenger Receptors (Scavenger Receptor)IBA
01/2007
1Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA
12/2006
14-O-carboxymethylascochlorinIBA
06/2006
1OxygenIBA
11/2005
1Superoxides (Superoxide)IBA
11/2005
1LigandsIBA
04/2005

Therapy/Procedure

1Lasers (Laser)
07/2008