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R A Harrington Selected Research

eptifibatide (Integrilin)

7/2002Does eptifibatide confer a greater benefit to patients with unstable angina than with non-ST segment elevation myocardial infarction? Insights from the PURSUIT Trial.
2/2002Patients with acute coronary syndromes without persistent ST elevation undergoing percutaneous coronary intervention benefit most from early intervention with protection by a glycoprotein IIb/IIIa receptor blocker.
12/2001Attenuation of rebound ischemia after discontinuation of heparin therapy by glycoprotein IIb/IIIa inhibition with eptifibatide in patients with acute coronary syndromes: observations from the platelet IIb/IIIa in unstable angina: receptor suppression using integrilin therapy (PURSUIT) trial.
7/2001Pharmacodynamics and pharmacokinetics of eptifibatide in patients with acute coronary syndromes: prospective analysis from PURSUIT.
3/2001Variation in patient management and outcomes for acute coronary syndromes in Latin America and North America: results from the Platelet IIb/IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy (PURSUIT) trial.
3/2001Prognostic importance of concomitant heparin with eptifibatide in acute coronary syndromes. PURSUIT Investigators. Platelet Glycoprotein IIb/IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy.
2/2001Therapeutic value of eptifibatide at community hospitals transferring patients to tertiary referral centers early after admission for acute coronary syndromes. PURSUIT Investigators.
12/2000Enhanced efficacy of eptifibatide administration in patients with acute coronary syndrome requiring in-hospital coronary artery bypass grafting. PURSUIT Investigators.
9/2000Management of patients with acute coronary syndromes in the United States by platelet glycoprotein IIb/IIIa inhibition. Insights from the platelet glycoprotein IIb/IIIa in unstable angina: receptor suppression using integrilin therapy (PURSUIT) trial.
9/2000Clinical and therapeutic profile of patients presenting with acute coronary syndromes who do not have significant coronary artery disease.The Platelet Glycoprotein IIb/IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy (PURSUIT) Trial Investigators.
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R A Harrington Research Topics

Disease

25Acute Coronary Syndrome
04/2009 - 01/2000
17Unstable Angina
07/2002 - 01/2000
16Myocardial Infarction
03/2005 - 02/2000
8Hemorrhage
04/2009 - 07/2000
6Infarction
07/2002 - 03/2000
3Ischemia
03/2005 - 06/2001
3Thrombocytopenia (Thrombopenia)
09/2000 - 07/2000
2Chest Pain (Chest Pains)
09/2000 - 03/2000
1Stroke (Strokes)
09/2001
1Transient Ischemic Attack
09/2001
1Heart Diseases (Heart Disease)
07/2001
1Myocardial Ischemia (Ischemic Heart Diseases)
03/2001
1Reperfusion Injury
01/2001
1Pathologic Constriction (Stenosis)
09/2000
1Cardiogenic Shock
09/2000
1Shock
09/2000
1Cardiovascular Diseases (Cardiovascular Disease)
08/2000
1Atherosclerosis
08/2000
1Heart Failure
06/2000

Drug/Important Bio-Agent (IBA)

20Glycoproteins (Glycoprotein)IBA
02/2002 - 01/2000
19eptifibatide (Integrilin)FDA Link
07/2002 - 01/2000
4MB Form Creatine KinaseIBA
02/2004 - 01/2000
4Platelet Membrane Glycoprotein IIbIBA
02/2001 - 01/2000
3paragonIBA
07/2005 - 06/2001
3Heparin (Liquaemin)FDA LinkGeneric
03/2005 - 03/2001
2DX 9065aIBA
03/2005 - 02/2004
1TicagrelorIBA
04/2009
1clopidogrel (Plavix)FDA Link
04/2009
1Factor Xa (Coagulation Factor Xa)IBA
03/2005
1Creatine Kinase (Creatine Phosphokinase)IBA
02/2004
1Warfarin (Coumadin)FDA LinkGeneric
09/2001
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
09/2001
1HormonesIBA
07/2001
1Trinitrotoluene (TNT)IBA
06/2001
1Troponin T (T, Troponin)IBA
06/2001
1Lipid AIBA
04/2001
1glucuronyl glucosamine glycan sulfate (Vessel)IBA
01/2001
1Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
09/2000
1lotrafibanIBA
08/2000
1abciximab (ReoPro)FDA Link
07/2000
1Hemoglobins (Hemoglobin)IBA
07/2000
1EnzymesIBA
06/2000
1Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
01/2000
1TroponinIBA
01/2000

Therapy/Procedure

3Coronary Artery Bypass (Coronary Artery Bypass Surgery)
04/2009 - 09/2000
1Transplants (Transplant)
04/2009
1Hormone Replacement Therapy (Therapy, Hormone Replacement)
07/2001
1Preoperative Period
09/2000
1Coronary Balloon Angioplasty (Percutaneous Transluminal Coronary Angioplasty)
07/2000
1Platelet Transfusion (Blood Platelet Transfusions)
07/2000