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Jürgen Harder Selected Research

Ribonuclease 7

1/2014Infection of keratinocytes with Trichophytum rubrum induces epidermal growth factor-dependent RNase 7 and human beta-defensin-3 expression.
8/2013Prenatal human skin expresses the antimicrobial peptide RNase 7.
1/2013IL-17A and IFN-γ synergistically induce RNase 7 expression via STAT3 in primary keratinocytes.
1/2012Antimicrobial RNases in cutaneous defense.
7/2011Ribonuclease 7 is a potent antimicrobial peptide within the human urinary tract.
7/2010Differential expression of antimicrobial peptides in margins of chronic wounds.
5/2010Enhanced expression and secretion of antimicrobial peptides in atopic dermatitis and after superficial skin injury.

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Jürgen Harder Research Topics

Disease

11Infection
11/2014 - 01/2005
6Atopic Dermatitis (Atopic Eczema)
07/2014 - 06/2007
5Inflammation
10/2013 - 02/2006
4Psoriasis (Pustulosis Palmaris et Plantaris)
11/2014 - 05/2010
2Crohn Disease (Crohn's Disease)
02/2014 - 06/2007
2Skin Diseases
10/2013 - 05/2011
2Neoplasms (Cancer)
08/2013 - 01/2007
2Infertility (Sterility)
08/2013 - 07/2011
2Bacterial Infections (Bacterial Infection)
10/2011 - 09/2002
2Wounds and Injuries (Trauma)
07/2010 - 02/2006
2Urinary Bladder Neoplasms (Bladder Cancer)
01/2008 - 07/2006
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
04/2007 - 01/2007
1Erysipelas
11/2014
1Soft Tissue Infections
11/2014
1Dermatomycoses (Dermatophytosis)
01/2014
1Acne Vulgaris
06/2013
1Bacteremia
10/2012
1Ulcer
07/2010
1Varicose Ulcer (Ulcer, Venous)
07/2010
1Carcinoma (Carcinomatosis)
06/2010
1Necrosis
12/2008
1Cystic Fibrosis (Mucoviscidosis)
06/2007
1Basal Cell Carcinoma (Rodent Ulcer)
04/2007
1Mouth Neoplasms (Oral Cancer)
01/2007
1Invasive Candidiasis
05/2005

Drug/Important Bio-Agent (IBA)

11PeptidesIBA
11/2014 - 01/2007
11Adenosine Monophosphate (AMP)IBA
11/2014 - 02/2006
7Ribonuclease 7IBA
01/2014 - 05/2010
5Proteins (Proteins, Gene)IBA
01/2013 - 01/2005
4beta-DefensinsIBA
11/2014 - 09/2002
2DNA (Deoxyribonucleic Acid)IBA
07/2014 - 05/2011
2Epidermal Growth Factor Receptor (EGF Receptor)IBA
01/2014 - 08/2013
2CAP18 lipopolysaccharide-binding protein (Bac4)IBA
10/2013 - 05/2011
2DefensinsIBA
10/2013 - 05/2005
2Bromodeoxyuridine (BrdU)IBA
01/2008 - 07/2006
1Interleukin-17 (Interleukin 27)IBA
02/2014
1Epidermal Growth Factor (EGF)IBA
01/2014
1RetinoidsIBA
06/2013
1Anti-Infective Agents (Microbicides)IBA
06/2013
1Ribonucleases (Ribonuclease)IBA
01/2012
1pimecrolimus (Elidel)FDA Link
10/2011
1Adrenal Cortex Hormones (Corticosteroids)IBA
10/2011
1Fura-2 (Fura 2)IBA
06/2010
1NF-kappa B (NF-kB)IBA
11/2009
1streptolysin OIBA
11/2009
1Interleukin-1alpha (Interleukin 1 alpha)IBA
12/2008
1CecropinsIBA
01/2008
1cecropin AIBA
01/2008
1Interleukin-8 (Interleukin 8)IBA
04/2007
1involucrinIBA
04/2007
1Messenger RNA (mRNA)IBA
04/2007
1OxidoreductasesIBA
07/2006
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
09/2002