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J M Gutiérrez Selected Research

Snake Venoms (Snake Venom)

7/2013Antivenom for snakebite envenoming in Sri Lanka: the need for geographically specific antivenom and improved efficacy.
10/2003Neutrophils do not contribute to local tissue damage, but play a key role in skeletal muscle regeneration, in mice injected with Bothrops asper snake venom.
5/2003Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants.
10/2002Evaluation of antivenoms in the neutralization of hyperalgesia and edema induced by Bothrops jararaca and Bothrops asper snake venoms.
12/2001Systemic cytokine response in children bitten by snakes in Costa Rica.
8/2001Pharmacological modulation of hyperalgesia induced by Bothrops asper (terciopelo) snake venom.
3/2001Dissociation of enzymatic and pharmacological properties of piratoxins-I and -III, two myotoxic phospholipases A2 from Bothrops pirajai snake venom.
11/2000Inhibition of local hemorrhage and dermonecrosis induced by Bothrops asper snake venom: effectiveness of early in situ administration of the peptidomimetic metalloproteinase inhibitor batimastat and the chelating agent CaNa2EDTA.
9/2000Snake venom metalloproteinases: their role in the pathogenesis of local tissue damage.
2/2000Comparative study on the ability of IgG and Fab sheep antivenoms to neutralize local hemorrhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom.

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J M Gutiérrez Research Topics

Disease

16Edema
06/2006 - 01/2000
9Hemorrhage
03/2011 - 01/2000
3Snake Bites (Snake Bite)
09/2014 - 09/2000
3Hyperalgesia
05/2003 - 08/2001
2Necrosis
02/2001 - 08/2000
1Ureterocele
07/2014
1Urinary Tract Infections (Urinary Tract Infection)
07/2014
1Vesico-Ureteral Reflux (Vesicoureteral Reflux)
07/2014
1Neoplasms (Cancer)
03/2011
1Hydrocephalus (Hydrocephaly)
03/2011
1Infection
03/2011
1Arthralgia (Joint Pain)
08/2007
1Arthritis (Polyarthritis)
08/2007
1Wounds and Injuries (Trauma)
12/2001
1Hemolysis
07/2001
1Thrombocytopenia (Thrombopenia)
04/2001
1Pain (Aches)
02/2001
1Fibrosis (Cirrhosis)
09/2000
1Ischemia
09/2000
1Gas Gangrene (Gangrene, Gas)
08/2000
1Bites and Stings (Sting)
07/2000
1Rupture
06/2000

Drug/Important Bio-Agent (IBA)

14VenomsIBA
06/2006 - 02/2000
10Snake Venoms (Snake Venom)IBA
07/2013 - 02/2000
4Liposomes (Liposome)IBA
03/2001 - 01/2000
3Antivenins (Antivenoms)IBA
07/2013 - 02/2000
3Phospholipases (Phospholipase)IBA
08/2001 - 02/2001
2Matrix MetalloproteinasesIBA
08/2007 - 09/2000
2Phospholipases A2 (Phospholipase A2)IBA
05/2003 - 03/2001
2AntibodiesIBA
05/2003 - 10/2002
2icatibantIBA
05/2003 - 08/2001
2BradykininIBA
05/2003 - 08/2001
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2003 - 09/2000
22,5-dichloro-4-bromophenol (B 2)IBA
05/2003 - 08/2001
2Artificial Membranes (Artificial Membrane)IBA
03/2001 - 06/2000
2batimastat (BB 94)IBA
11/2000 - 07/2000
2Metalloproteases (Metalloproteinases)IBA
09/2000 - 07/2000
2Creatine Kinase (Creatine Phosphokinase)IBA
08/2000 - 06/2000
1Immunoglobulin FragmentsIBA
09/2014
1Furosemide (Lasix)FDA LinkGeneric
07/2014
1CoagulaseIBA
03/2011
1linezolid (Zyvox)FDA Link
03/2011
1Adrenal Cortex Hormones (Corticosteroids)IBA
03/2011
1NG-Nitroarginine Methyl Ester (L-NAME)IBA
06/2006
1Nitric Oxide (Nitrogen Monoxide)FDA Link
06/2006
1pimagedine (aminoguanidine)IBA
06/2006
1Nitric Oxide Synthase (NO Synthase)IBA
06/2006
1Serotonin (5 Hydroxytryptamine)IBA
05/2003
1Promethazine (Promet)FDA LinkGeneric
05/2003
1Interleukin-1 (Interleukin 1)IBA
05/2003
1GuanethidineFDA Link
05/2003
1Indomethacin (Indometacin)FDA LinkGeneric
05/2003
1Sympathomimetics (Sympathomimetic Amines)IBA
05/2003
1Methysergide (Sansert)FDA Link
05/2003
1Yohimbine (Yocon)IBA
05/2003
1Atenolol (Tenormin)FDA LinkGeneric
05/2003
1Prazosin (Minipress)FDA LinkGeneric
05/2003
14-bromophenacyl bromideIBA
05/2003
1Phospholipases AIBA
05/2003
1Histamine (Histamine Dihydrochloride)FDA Link
05/2003
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
05/2003
1CytokinesIBA
12/2001
1Edetic Acid (EDTA)FDA Link
09/2001
1CrotoxinIBA
09/2001
1Dexamethasone (Maxidex)FDA LinkGeneric
08/2001
1LeukotrienesIBA
08/2001
1pyridyldithioethylamineIBA
07/2001
1neuwiedaseIBA
06/2001
1aspercetinIBA
04/2001
1Fish VenomsIBA
02/2001
1Type C PhospholipasesIBA
08/2000
1Caseins (Casein)FDA Link
07/2000
1Heparin (Liquaemin)FDA LinkGeneric
06/2000
1Immunoglobulin G (IgG)IBA
02/2000
1Immunoglobulin Fab FragmentsIBA
02/2000
1hemorrhagic metalloproteinaseIBA
01/2000

Therapy/Procedure

1Electrodes (Electrode)
07/2014
1General Anesthesia
07/2014
1Craniotomy
03/2011
1Analgesia
08/2007
1Intramuscular Injections
06/2006
1Injections
05/2003
1Aftercare (After-Treatment)
09/2001
1Subcutaneous Injections
06/2001
1Intraperitoneal Injections
01/2000